RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(18), P. 12475 - 12495
Published: Jan. 1, 2024
The
study
sets
out
to
show
the
positive
impact
of
sulfur
vacancy
engineering
on
structural,
morphological,
optical,
electrical,
and
photoelectrochemical
(PEC)
properties
Sb
Science,
Journal Year:
2023,
Volume and Issue:
381(6665), P. 1474 - 1479
Published: Sept. 28, 2023
Nitrogen
scanning
in
aryl
fragments
is
a
valuable
aspect
of
the
drug
discovery
process,
but
current
strategies
require
time-intensive,
parallel,
bottom-up
synthesis
each
pyridyl
isomer
because
lack
direct
carbon-to-nitrogen
(C-to-N)
replacement
reactions.
We
report
site-directable
C-to-N
reaction
allowing
unified
access
to
various
pyridine
isomers
through
nitrene-internalization
process.
In
two-step,
one-pot
procedure,
azides
are
first
photochemically
converted
3
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(47), P. 8451 - 8456
Published: Nov. 16, 2023
The
three-component
reactions
of
enaminones,
disulfides,
and
alcohols
for
the
synthesis
polyfunctionalized
alkenes
have
been
realized
via
C-H
C-N
bond
transformation
on
enaminones.
proceed
in
a
novel
"alkene-to-alkene"
difunctionalization
mode
without
using
any
transition
metal.
application
alkene
products
divergent
sulfenyl
heteroaryls,
including
sulfenylated
pyrazoles,
pyrimidines,
isoxazoles,
simple
annulation
has
also
verified.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(9), P. 2638 - 2664
Published: Jan. 1, 2024
This
review
describes
the
recent
advances
in
different
reaction
types
and
catalytic
systems
for
construction
of
C–NAr
S–NAr
bonds
by
nitroaromatic
reductive
cross-coupling.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: May 4, 2024
Abstract
Developing
skeletal
editing
tools
is
not
a
trivial
task,
and
realizing
the
corresponding
single-atom
transmutation
in
ring
system
without
altering
size
even
more
challenging.
Here,
we
introduce
strategy
that
enables
polycyclic
arenols,
highly
prevalent
motif
bioactive
molecules,
to
be
readily
converted
into
N
-heteroarenes
through
carbon–nitrogen
transmutation.
The
reaction
features
selective
nitrogen
insertion
C–C
bond
of
arenol
frameworks
by
azidative
dearomatization
aryl
migration,
followed
ring-opening,
ring-closing
(ANRORC)
achieve
carbon-to-nitrogen
aromatic
framework
arenol.
Using
widely
available
arenols
as
-heteroarene
precursors,
this
alternative
approach
allows
streamlined
assembly
complex
heteroaromatics
with
broad
functional
group
tolerance.
Finally,
pertinent
transformations
products,
including
synthesis
biheteroarene
skeletons,
were
conducted
exhibited
significant
potential
materials
chemistry.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(14), P. 4041 - 4053
Published: Jan. 1, 2024
This
paper
primarily
focuses
on
the
editing
of
nitrogen
atoms,
encompassing
insertion
N,
substitution
C
with
and
utilization
15
N
in
place
14
for
construction
N-heterocycles.
Chem,
Journal Year:
2023,
Volume and Issue:
9(12), P. 3685 - 3695
Published: Nov. 14, 2023
Ortho-phenylenediamines
are
aromatic
molecules
featuring
two
vicinal
N-substituents
with
strong
structural
relevance
to
the
development
of
bioactive
materials.
These
derivatives
currently
prepared
from
ortho-halogenated
nitrobenzenes
via
multistep
synthetic
sequences.
Here,
we
report
a
conceptually
different
approach
where
and
amines
can
be
directly
converted
into
ortho-phenylenediamines
without
need
for
ortho-halogenation
following
stepwise
manipulation.
This
strategy
occurs
under
simple
blue
light
irradiation
introduces
an
alternative
retrosynthetic
tactic
whereby
amine
coupling
partner
"seems"
displace
nitro
group
that
shifts
its
ortho
position
while
being
reduced
amidated
in
one-pot
process.
Mechanistically,
this
process
capitalizes
on
conversion
corresponding
single
nitrenes,
which
undergo
series
N-insertion,
electrocyclic
ring
expansion,
addition,
contraction
en
route
ortho-phenylenediamines.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(20), P. 14136 - 14148
Published: April 20, 2024
An
unprecedented
chiral
bisphosphine-catalyzed
asymmetric
Staudinger/aza-Wittig
reaction
of
2,2-disubstituted
cyclohexane-1,3-diones
is
reported,
enabling
the
facile
access
a
broad
range
cis-3a-arylhydroindoles
in
high
yields
with
excellent
enantioselectivities.
The
key
to
success
this
work
relies
on
first
application
bisphosphine
DuanPhos
reaction.
effective
reductive
system
has
been
established
address
challenging
PV═O/PIII
redox
cycle
associated
catalyst.
In
addition,
comprehensive
experimental
and
computational
investigations
were
carried
out
elucidate
mechanism
Leveraging
newly
developed
chemistry,
enantioselective
total
syntheses
several
crinine-type
Amaryllidaceae
alkaloids,
including
(+)-powelline,
(+)-buphanamine,
(+)-vittatine,
(+)-crinane,
have
accomplished
remarkable
conciseness
efficiency.
This
review
aims
to
provide
a
comprehensive
overview
of
the
expanding
utility
nitroarenes
and
their
potential
for
future
applications
in
synthetic
organic
chemistry.