Impending extinction crisis of the world’s primates: Why primates matter

Science Advances, Journal Year: 2017, Volume and Issue: 3(1)

Published: Jan. 6, 2017

Impending extinction of the world’s primates due to human activities; immediate global attention is needed reverse trend.

Language: Английский

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Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

Proceedings of the National Academy of Sciences, Journal Year: 2016, Volume and Issue: 113(9)

Published: Feb. 16, 2016

Significance Hepatocellular carcinoma is the second most deadly cancer type globally, requiring development of alternative or complementary therapeutic and prophylactic methods. Here, when feeding a mouse model with novel probiotic mixture 1 wk before tumor inoculation, we observed reduction weight size by 40% compared control. Our results revealed that probiotics’ beneficial effect closely related abundance certain bacteria produce antiinflammatory metabolites, which subsequently regulate proinflammatory immune cell population via crosstalk between gut tumor. We believe our study highlights extraordinary potential probiotics in extraintestine cancers can be adapted to other cancers.

Language: Английский

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Application of eco-compatible biochar in anaerobic digestion to relieve acid stress and promote the selective colonization of functional microbes

Water Research, Journal Year: 2014, Volume and Issue: 68, P. 710 - 718

Published: Nov. 4, 2014

Language: Английский

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A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota

Food & Function, Journal Year: 2017, Volume and Issue: 8(12), P. 4644 - 4656

Published: Jan. 1, 2017

Resveratrol and quercetin, widely found in foods vegetables, are plant polyphenols reported to have a wide range of biological activities. Despite their limited bioavailabilities, both resveratrol quercetin known exhibit anti-inflammation anti-obesity effects. We hypothesized that gut microbiota may be potential target for prevent the development obesity. The aim this research was confirm whether combination (CQR) could restore dysbiosis induced by high-fat diet (HFD). In study, Wistar rats were divided into three groups: normal (ND) group, HFD group CQR group. treated with administered [30 mg per kg body weight (BW) day] [15 oral gavage. At end 10 weeks, reduced gain visceral (epididymal, perirenal) adipose tissue weight. Moreover, also serum lipids, attenuated inflammatory markers [interleukin (IL)-6, tumor necrosis factor (TNF)-α, monocyte chemotactic protein (MCP)-1] reversed biochemical parameters (adiponectin, insulin, leptin, etc.). Importantly, our results demonstrated modulate composition. 16S rRNA gene sequencing revealed had an impact on microbiota, decreasing Firmicutes (P < 0.05) proportion Bacteroidetes = 0.052). significantly inhibited relative abundance Desulfovibrionaceae 0.01), Acidaminococcaceae 0.05), Coriobacteriaceae Bilophila Lachnospiraceae its genus Lachnoclostridium 0.001), which potentially related diet-induced compared Bacteroidales_S24-7_group Christensenellaceae Akkermansia Ruminococcaceae 0.01) genera Ruminococcaceae_UCG-014 Ruminococcaceae_UCG-005 effect relieving HFD-induced obesity, markedly increased Overall, these indicated administration beneficial effects ameliorating obesity reducing dysbiosis.

Language: Английский

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Conservation biology needs a microbial renaissance: a call for the consideration of host-associated microbiota in wildlife management practices

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2019, Volume and Issue: 286(1895), P. 20182448 - 20182448

Published: Jan. 23, 2019

The central aim of conservation biology is to understand and mitigate the effects human activities on biodiversity. To successfully achieve this objective, researchers must take an interdisciplinary approach that fully considers effects, both direct indirect, anthropogenic disturbances wildlife physiology health. A recent surge in research has revealed host-associated microbiota—the archaeal, bacterial, fungal viral communities residing inside organisms—profoundly influence animal health, these microbial can be drastically altered by activities. Therefore, practitioners should consider disruption diversity as a serious threat populations. Despite tremendous potential for microbiome improve outcomes, few efforts have been made truly integrate fields. In review, we call renaissance biology, where biodiversity microbiota recognized essential component management practices. Using evidence from existing literature, will examine known approaches maintaining objectives.

Language: Английский

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Biochar alleviates combined stress of ammonium and acids by firstly enriching Methanosaeta and then Methanosarcina

Water Research, Journal Year: 2015, Volume and Issue: 90, P. 34 - 43

Published: Dec. 19, 2015

Language: Английский

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Marked seasonal variation in the wild mouse gut microbiota

The ISME Journal, Journal Year: 2015, Volume and Issue: 9(11), P. 2423 - 2434

Published: May 29, 2015

Abstract Recent studies have provided an unprecedented view of the microbial communities colonizing captive mice; yet host and environmental factors that shape rodent gut microbiota in their natural habitat remain largely unexplored. Here, we present results from a 2-year 16 S ribosomal RNA gene sequencing-based survey wild wood mice (Apodemus sylvaticus) two nearby woodlands. Similar to other mammals, were colonized by 10 bacterial phyla dominated Firmicutes, Bacteroidetes Proteobacteria. Within Lactobacillus genus was most abundant. Putative pathogens widespread often abundant members mouse microbiota. Among suite extrinsic (environmental) intrinsic (host-related) examined, seasonal changes driving qualitative quantitative differences In both years observed strong shift community structure, potentially due transition insect- seed-based diet. This involved decreased levels Lactobacillus, increased Alistipes (Bacteroidetes phylum) Helicobacter. We also detected more subtle but statistically significant associations between biogeography, sex, reproductive status co-colonization with enteric nematodes. These suggest major role shaping temporal variations structure within populations.

Language: Английский

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The human microbiome in evolution

BMC Biology, Journal Year: 2017, Volume and Issue: 15(1)

Published: Dec. 1, 2017

The trillions of microbes living in the gut—the gut microbiota—play an important role human biology and disease. While much has been done to explore its diversity, a full understanding our microbiomes demands evolutionary perspective. In this review, we compare from populations, placing them context humanity’s near distant animal relatives. We discuss potential mechanisms generate host-specific microbiome configurations consequences disrupting those configurations. Finally, propose that broader phylogenetic perspective is useful for underlying human–microbiome interactions.

Language: Английский

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Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes

The ISME Journal, Journal Year: 2018, Volume and Issue: 13(3), P. 576 - 587

Published: July 11, 2018

Language: Английский

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The Gut Microbiota Appears to Compensate for Seasonal Diet Variation in the Wild Black Howler Monkey (Alouatta pigra)

Microbial Ecology, Journal Year: 2014, Volume and Issue: 69(2), P. 434 - 443

Published: Dec. 19, 2014

Language: Английский

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