Nanostructures and nanoparticles as medical diagnostic imaging contrast agents: A review DOI
Nikiwe Mhlanga,

Ntsoaki Mphuthi,

Hendriëtte Van der Walt

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102233 - 102233

Published: Aug. 5, 2024

Language: Английский

Inorganic Nanoparticles and Blood-Brain Barrier Modulation: Advancing Targeted Neurological Therapies DOI
Zahra Razavi, F. S. Razavi,

Seyed Sina Alizadeh

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 287, P. 117357 - 117357

Published: Feb. 5, 2025

Language: Английский

Citations

5
Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study DOI Creative Commons
Rafael Leandro Fernandes Melo, Dayana Nascimento Dari, Francisco Izaias da Silva Aires

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1207 - 1225

Published: Jan. 3, 2025

Manufacturing bioactive materials for drug delivery involves developing that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is optimize therapeutic efficacy reduce side effects by combining knowledge from engineering, biology, pharmacology. This study presents detailed bibliometric analysis, exploring the keywords "manufacturing," "bioactive materials," "drug delivery" identify highlight significant advancements field. From Web of Science, 36,504 articles were analyzed, 171 selected deeper identifying key journals, countries, institutions, authors. results field's interdisciplinary nature, grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, glass, tissue engineering. Future research this area will focus on more effective precise systems using technologies like 3D printing nanotechnology enhance customization control release, aiming efficient therapies.

Language: Английский

Citations

4
Eco-biofabrication of silver nanoparticles from Azadirachta indica, Gymnema sylvestre, and Moringa oleifera for lung cancer treatment DOI Creative Commons

T Sudalai Muthu,

Ravi Adusumalli,

Sathish Kumar Vemuri

et al.

Journal of the Egyptian National Cancer Institute, Journal Year: 2025, Volume and Issue: 37(1)

Published: Jan. 6, 2025

Silver nanoparticles (AgNPs) derived from natural sources have garnered significant attention due to their unique properties and eco-friendly production methods. With lung cancer remaining a major global health issue, there is continuous need for novel effective therapeutic approaches beyond conventional treatments such as chemotherapy, immunotherapy, targeted therapies.

Language: Английский

Citations

4
A Comprehensive Review on the Green Synthesis of Nanoparticles: Advancements in Biomedical and Environmental Applications DOI
Dharmalingam Kirubakaran,

Jamith Basha Abdul Wahid,

Natchimuthu Karmegam

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Language: Английский

Citations

4
Revolutionizing Prostate Cancer Therapy: Artificial intelligence – based Nanocarriers for Precision Diagnosis and Treatment DOI
Moein Shirzad,

Afsaneh Salahvarzi,

Sobia Razzaq

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104653 - 104653

Published: Feb. 1, 2025

Language: Английский

Citations

3
Advancements in Cancer Treatment: Harnessing the Synergistic Potential of Graphene-Based Nanomaterials in Combination Therapy DOI
A. Keyvani,

Parizad Mohammadnejad,

Hamidreza Pazoki–Toroudi

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Combination therapy, which involves using multiple therapeutic modalities simultaneously or sequentially, has become a cornerstone of modern cancer treatment. Graphene-based nanomaterials (GBNs) have emerged as versatile platforms for drug delivery, gene and photothermal therapy. These materials enable synergistic approach, improving the efficacy treatments while reducing side effects. This review explores roles graphene, graphene oxide (GO), quantum dots (GQDs) in combination therapies highlights their potential to enhance immunotherapy targeted therapies. The large surface area high drug-loading capacity facilitate codelivery agents, promoting sustained release. GQDs, with unique optical properties, offer real-time imaging capabilities, adding another layer precision However, challenges such biocompatibility, long-term toxicity, scalability need be addressed ensure clinical safety. Preclinical studies show promising results GBNs, suggesting revolutionize treatment through innovative

Language: Английский

Citations

2
Interactions and communications in lung tumor microenvironment: Chemo/radiotherapy resistance mechanisms and therapeutic targets DOI
Feng Yuan, Ying Jiang, Lin Yang

et al.

Journal of drug targeting, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 33

Published: Jan. 15, 2025

The lung tumor microenvironment is composed of various cell types, including cancer cells, stromal and immune as well extracellular matrix (ECM). These cells surrounding ECM create a stiff, hypoxic, acidic, immunosuppressive that can augment the resistance tumors to different forms death facilitate invasion metastasis. This environment induce chemo/radiotherapy by inducing anti-apoptosis mediators such phosphoinositide 3-kinase (PI3K)/Akt, signal transducer activator transcription 3 (STAT3), nuclear factor κB (NF-κB), leading exhaustion antitumor immunity further chemo/radiotherapy. In addition, resist boosting multidrug mechanisms antioxidant defense systems within other TME components. this review, we discuss interactions communications between these components also effects hypoxia, evasion, remodeling on resistance. Finally, review current strategies in preclinical clinical studies, inhibition checkpoint molecules, chemoattractants, cytokines, growth factors, programmed 1 (PD-1), insulin-like 2 (IGF-2) for targeting overcome chemotherapy radiotherapy.

Language: Английский

Citations

2
Nanotechnology-based biomedical devices in the cancer diagnostics and therapy DOI
Junaid Tantray, Akhilesh Patel,

Hiba Parveen

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(2)

Published: Jan. 20, 2025

Language: Английский

Citations

2
Applications of liposomes and lipid nanoparticles in cancer therapy: current advances and prospects DOI Creative Commons
Zhe Cheng, Huichao Huang, Mingru Yin

et al.

Experimental Hematology and Oncology, Journal Year: 2025, Volume and Issue: 14(1)

Published: Jan. 31, 2025

Liposomes and lipid nanoparticles are common lipid-based drug delivery systems play important roles in cancer treatment vaccine manufacture. Although significant progress has been made with these nanocarriers recent years, efficient clinical translation of active targeted liposomal remains extremely challenging. In this review, we focus on liposomes, stimuli-responsive strategy combined therapy treatment. We also summarize advances liposome nanoparticle applications nucleic acid tumor vaccination. addition, discuss limitations challenges the nanomaterials make recommendations for future research therapy.

Language: Английский

Citations

2
Spatiotemporal manipulation metal–organic frameworks as oral drug delivery systems for precision medicine DOI
Zhao Wang, Jiao Chen,

Renchi Gao

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 502, P. 215615 - 215615

Published: Dec. 20, 2023

Language: Английский

Citations

38