Organometallics,
Journal Year:
2022,
Volume and Issue:
41(23), P. 3499 - 3503
Published: Nov. 23, 2022
Secondary
phosphine
oxides
(SPOs)
are
often
difficult
coupling
partners
for
transition-metal-catalyzed
C–H
phosphorylation
reactions.
Herein,
a
series
of
SPO-RhIII
complexes
relevant
to
RhIII-catalyzed
was
isolated
and
fully
characterized.
Detailed
research
on
their
reactivities
in
rhodation
indicates
the
crucial
role
suitable
base
reduce
deactivation
RhIII
by
SPOs.
Finally,
using
silver
carbonate
as
both
an
oxidant,
efficient
aryl
with
diarylphosphine
developed.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(21), P. 3956 - 3960
Published: May 18, 2023
A
general
and
robust
strategy
for
the
synthesis
of
phosphonylated
spirocyclic
indolines
has
been
developed
through
Cp2Fe-catalyzed
electrochemical
dearomaztizaion
indoles,
which
proven
challenging
to
achieve
via
chemical
oxidants.
range
3,3-spiroindolines
were
obtained
in
moderate
good
yields
with
excellent
diastereoselectivities.
The
synthetic
application
was
further
illustrated
by
its
easy
scalability
antitumor
activity
product.
Beilstein Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
21, P. 770 - 797
Published: April 16, 2025
In
this
review,
we
describe
recent
advances
in
electrochemical
green
methods
for
the
synthesis
of
various
organophosphorus
compounds
through
formation
phosphorus–carbon,
phosphorus–nitrogen,
phosphorus–oxygen,
phosphorus–sulfur,
and
phosphorus–selenium
bonds.
The
impact
different
electrodes
is
also
discussed
matter.
Graphite,
platinum,
RVC,
nickel
have
been
used
extensively
compounds.
made
method
a
promising
preparing
structures.
This
review
an
introduction
to
encourage
scientists
use
electrosynthesis
as
green,
precise,
low-cost
prepare
phosphorous
Frontiers in Chemistry,
Journal Year:
2022,
Volume and Issue:
10
Published: Nov. 3, 2022
The
activation
of
C–H
bond,
and
its
direct
one-step
functionalization,
is
one
the
key
synthetic
methodologies
that
provides
access
to
a
variety
practically
significant
compounds.
Particular
attention
focused
on
modifications
obtained
at
final
stages
synthesis
complicated
molecules,
which
requires
high
tolerance
presence
existing
functional
groups.
Phosphorus
an
indispensable
element
life,
phosphorus
chemistry
now
experiencing
renaissance
due
new
emerging
applications
in
medicinal
chemistry,
materials
(polymers,
flame
retardants,
organic
electronics,
photonics),
agricultural
(herbicides,
insecticides),
catalysis
(ligands)
other
important
areas
science
technology.
In
this
regard,
search
for
new,
more
selective,
low-waste
routes
become
relevant.
context,
electrosynthesis
has
proven
be
eco-efficient
convenient
approach
many
respects,
where
reagents
are
replaced
by
electrodes,
reactants
applied
potential
determines
their
“oxidizing
or
reducing
ability”.
An
electrochemical
such
processes
being
developed
rapidly
demonstrates
some
advantages
over
traditional
classical
methods
C-H
phosphorylation.
main
reasons
success
exclusion
excess
from
reaction
system:
as
oxidants,
agents,
sometimes
metal
and/or
improvers,
challenge
isolation,
increase
wastes
reduce
yield
frequent
incompatibility
with
these
Ideal
conditions
include
electron
reactant
(regulated
potential)
by-products
hydrogen
hydrocarbon.
review
summarizes
analyzes
achievements
preparation
various
derivatives
carbon-phosphorus
bonds,
collects
data
redox
properties
most
commonly
used
precursors.
Electrochemically
induced
reactions
both
without
catalyst
metals,
competitive
oxidation
precursors
leads
either
bond
generation
phosphorus-centered
radicals
(radical
cations)
states
will
examined.
focuses
publications
past
5
years.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(24), P. 17521 - 17526
Published: Nov. 22, 2023
An
efficient
and
environmentally
friendly
electrochemical
synthesis
of
phosphorylated
oxindoles
indolo[2,1-a]isoquinolin-6(5H)-ones
mediated
by
readily
available
Cp2Fe
has
been
developed,
which
illustrated
a
broad
substrate
scope
diverse
functional
group
compatibility.
This
protocol
featured
an
external
oxidant-free
process
was
at
room
temperature,
proposed
to
be
driven
the
anodic
oxidation
Cp2Fe.
Synthesis,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 5, 2025
Abstract
Ferrocene,
a
highly
redox-stable
organometallic
compound
with
distinctive
sandwich-like
structure,
has
significantly
influenced
the
fields
of
electrochemistry,
materials
science,
and
medicinal
chemistry.
Modifying
ferrocene
core
its
side
chains
is
crucial
for
fine-tuning
redox
properties,
solubility,
stability,
thereby
enhancing
performance
in
various
applications.
This
review
discusses
synthesis
compounds
potentially
relevant
to
electrochemical
applications,
focusing
on
recent
strategies
nondirected
C–H
functionalization
diverse
reactions
side-chain
modifications.
Advances
activation
ferrocenes
have
been
facilitated
by
catalytic
methods
utilizing
Pd,
Ir,
Au,
In,
Fe
catalysts,
as
well
through
photoredox
techniques.
Furthermore,
are
modified
via
range
mild
transformations
compatible
core,
including
substitution
annulation.
These
advancements
synthesizing
derivatives
broadened
their
potential
notably
electron-transfer
mediators,
energy-storage
systems,
sensors.
1
Introduction
2
Nondirected
Activation
Ferrocene
Its
Derivatives
3
Side-Chain
Modification
4
Applications
Electrochemistry
5
Conclusion
Synthesis,
Journal Year:
2023,
Volume and Issue:
55(18), P. 2817 - 2832
Published: April 12, 2023
Abstract
Electrochemical
synthesis
has
recently
emerged
as
an
environmentally
benign
method
for
synthesizing
value-added
fine
chemicals.
Its
unique
reactivity
attracted
significant
interests
of
synthetic
chemists
to
develop
new
redox
chemistries.
However,
compared
conventional
chemistry,
the
increased
complexity
caused
by
electrode
materials,
supporting
electrolytes,
and
setup
configurations
create
obstacles
efficient
reaction
discovery
optimization.
The
recent
increasing
adoption
high-throughput
experimentation
(HTE)
in
chemistry
significantly
expedites
development.
Considering
potential
implementing
HTE
electrosynthesis
tackle
challenges
parameter
space,
this
short
review
aims
at
providing
advances
technology
electrosynthesis,
including
electrocatalysts
screening,
device
miniaturization,
electroanalytical
methods,
artificial
intelligence,
system
integration.
discussed
contents
also
cover
some
topics
electrochemistry
areas
other
than
hoping
spark
inspirations
readers
use
interdisciplinary
techniques
solve
electrochemistry.
1
Introduction
2
Parallelized
Reaction
Screening
3
High-Throughput
Electrocatalysts
4
Miniaturization
Devices
5
Analytical
Methods
Electrosynthesis
6
Artificial
Intelligence
7
Integrated
Systems
8
Conclusion
Outlook
Organic Letters,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 26, 2024
A
chlorotrimethylsilane
(TMSCl)-mediated
cascade
phosphorylation
and
cycloisomerization
of
enynones
with
diphenylphosphine
oxides
is
presented.
This
methodology
enables
the
highly
selective
synthesis
monophosphorylated
2
