Hydrogel machines

Materials Today, Journal Year: 2020, Volume and Issue: 36, P. 102 - 124

Published: Jan. 28, 2020

Language: Английский

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Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties

Chemical Reviews, Journal Year: 2021, Volume and Issue: 121(8), P. 4309 - 4372

Published: April 12, 2021

Hydrogels are polymer networks infiltrated with water. Many biological hydrogels in animal bodies such as muscles, heart valves, cartilages, and tendons possess extreme mechanical properties including being extremely tough, strong, resilient, adhesive, fatigue-resistant. These also critical for hydrogels' diverse applications ranging from drug delivery, tissue engineering, medical implants, wound dressings, contact lenses to sensors, actuators, electronic devices, optical batteries, water harvesters, soft robots. Whereas numerous have been developed over the last few decades, a set of general principles that can rationally guide design using different materials fabrication methods various remain central need field materials. This review is aimed at synergistically reporting: (i) achieve physical properties, (ii) implementation strategies unconventional networks, (iii) future directions orthogonal multiple combined mechanical, physical, chemical, properties. Because these based on generic they applicable other elastomers organogels. Overall, will not only provide comprehensive systematic guidelines rational materials, but provoke interdisciplinary discussions fundamental question: why does nature select constitute major parts bodies?

Language: Английский

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Technology Roadmap for Flexible Sensors

ACS Nano, Journal Year: 2023, Volume and Issue: 17(6), P. 5211 - 5295

Published: March 9, 2023

Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.

Language: Английский

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Electrical bioadhesive interface for bioelectronics

Nature Materials, Journal Year: 2020, Volume and Issue: 20(2), P. 229 - 236

Published: Sept. 28, 2020

Language: Английский

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Polymeric Tissue Adhesives

Chemical Reviews, Journal Year: 2021, Volume and Issue: 121(18), P. 11336 - 11384

Published: Jan. 28, 2021

Polymeric tissue adhesives provide versatile materials for wound management and are widely used in a variety of medical settings ranging from minor to life-threatening injuries. Compared the traditional methods closure (i.e., suturing stapling), they relatively easy use, enable rapid application, introduce minimal damage. Furthermore, can act as hemostats control bleeding tissue-healing environment at site. Despite their numerous current applications, still face several limitations unresolved challenges (e.g., weak adhesion strength poor mechanical properties) that limit leaving ample room future improvements. Successful development next-generation will likely require holistic understanding chemical physical properties tissue-adhesive interface, fundamental mechanisms adhesion, requirements specific clinical applications. In this review, we discuss set rational guidelines design adhesives, recent progress field along with examples commercially available those under development, tissue-specific considerations, finally potential functions adhesives. Advances open new avenues care potentially potent therapeutics various

Language: Английский

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Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing

Advanced Science, Journal Year: 2021, Volume and Issue: 8(8)

Published: March 5, 2021

Treatment of wounds in special areas is challenging due to inevitable movements and difficult fixation. Common cotton gauze suffers from incomplete joint surface coverage, confinement movement, lack antibacterial function, frequent replacements. Hydrogels have been considered as good candidates for wound dressing because their flexibility biocompatibility. Nevertheless, the adhesive, mechanical, properties conventional hydrogels are not satisfactory. Herein, cationic polyelectrolyte brushes grafted bacterial cellulose (BC) nanofibers introduced into polydopamine/polyacrylamide hydrogels. The 1D polymer rigid BC backbones enhance mechanical property hydrogels, realizing high tensile strength (21-51 kPa), large strain (899-1047%), ideal compressive property. Positively charged quaternary ammonium groups tethered provide long-lasting promote crawling proliferation negatively epidermis cells. Moreover, rich catechol capable adhering various surfaces, meeting adhesive demand movement areas. With above merits, demonstrate less inflammatory response faster healing speed vivo on rats. Therefore, multifunctional show stable covering, little displacement, antibacteria, fast healing, demonstrating promise dressing.

Language: Английский

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Recent advances in wet adhesives: Adhesion mechanism, design principle and applications

Progress in Polymer Science, Journal Year: 2021, Volume and Issue: 116, P. 101388 - 101388

Published: March 10, 2021

Language: Английский

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Hydrogel interfaces for merging humans and machines

Nature Reviews Materials, Journal Year: 2022, Volume and Issue: 7(12), P. 935 - 952

Published: Oct. 13, 2022

Language: Английский

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A Solvent‐Exchange Strategy to Regulate Noncovalent Interactions for Strong and Antiswelling Hydrogels

Advanced Materials, Journal Year: 2020, Volume and Issue: 32(52)

Published: Nov. 9, 2020

Abstract Physical hydrogels from existing polymers consisting of noncovalent interacting networks are highly desired due to their well‐controlled compositions and environmental friendliness; therefore, applied as adhesives, artificial tissues, soft machines. Nevertheless, these gels have suffered weak mechanical strength low water resistance. Current methodologies used fabricate mainly involve the freezing–thawing process (cryogels), which complicated in preparation short adjustment polymer conformation. Here, taking merits bonds adjustability reversibility, a solvent‐exchange strategy is developed construct class exogels. Based on exchange good solvent subsequently poor one, intra‐ interpolymer interactions initially suppressed then recovered, resulting dissolving cross‐linking polymers, respectively. Key this approach solvent, favors stretched conformation homogenize network, forming cross‐linked hydrogel with remarkable stiffness, toughness, antiswelling properties, thus underwater adhesive performance. The exogels highlight facile but effective turning consequently achieve rational design enhanced hydrogel‐based materials.

Language: Английский

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Bioadhesive ultrasound for long-term continuous imaging of diverse organs

Science, Journal Year: 2022, Volume and Issue: 377(6605), P. 517 - 523

Published: July 28, 2022

Continuous imaging of internal organs over days could provide crucial information about health and diseases enable insights into developmental biology. We report a bioadhesive ultrasound (BAUS) device that consists thin rigid probe robustly adhered to the skin via couplant made soft, tough, antidehydrating, hydrogel-elastomer hybrid. The BAUS provides 48 hours continuous diverse organs, including blood vessels, muscle, heart, gastrointestinal tract, diaphragm, lung. diagnostic monitoring tools for various diseases.

Language: Английский

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