A Janus Hydrogel Wet Adhesive for Internal Tissue Repair and Anti‐Postoperative Adhesion

Advanced Functional Materials, Journal Year: 2020, Volume and Issue: 30(49)

Published: Sept. 11, 2020

Abstract Despite rapid development of adhesive hydrogels, the typical double‐sided adhesives fail to adhere wet tissues and concurrently prevent postoperative tissue adhesion, thus severely limiting their applications in repair internal tissues. Herein, a negatively charged carboxyl‐containing hydrogel is gradiently, electrostatically complexed with cationic oligosaccharide by one‐sided dipping method form novel Janus whose two‐side faces demonstrate strikingly distinct nonadhesive properties. The lightly surface demonstrates instant robust adhesion various biological even under water since phase separation induced electrostatic complexation increases hydrophobicity drainage capacity. Intriguingly, highly non‐adhesive due complete neutralization carboxyls hydrogels. can be used replace traditional sutures treat gastric perforation rabbits. Animal experiment outcomes reveal that one side firmly glued stomach tissue, other facing outward efficiently adhesion. Molecular simulation elucidates importance for selecting polymer species. It believed gradient polyelectrolyte establish new direction create tissue/organ simultaneous prevention post‐operative

Language: Английский

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Mixed-dimensional MXene-hydrogel heterostructures for electronic skin sensors with ultrabroad working range

Science Advances, Journal Year: 2020, Volume and Issue: 6(48)

Published: Nov. 27, 2020

Heterogeneous integration of robust hydrogel and soft MXene shows multifunctional sensing.

Language: Английский

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Barnacle Cement Proteins‐Inspired Tough Hydrogels with Robust, Long‐Lasting, and Repeatable Underwater Adhesion

Advanced Functional Materials, Journal Year: 2020, Volume and Issue: 31(11)

Published: Dec. 28, 2020

Abstract The development of adhesives that can achieve robust and repeatable adhesion to various surfaces underwater is promising; however, this remains a major challenge primarily because the surface hydration layer weakens interfacial molecular interactions. Herein, strategy proposed develop tough hydrogels are robust, reusable, long‐lasting for adhesion. Hydrogels from cationic aromatic monomers with an aromatic‐rich composition inspired by amino acid residuals in barnacle cement proteins synthesized. mechanically strong (elastic modulus 0.35 MPa, fracture stress 1.0 strain 720%), owing interchain π–π cation–π In water, firmly adhere diverse through electrostatic hydrophobic interactions (adhesion strength 180 kPa), which allows instant reversibility (50 times). Moreover, hydrogel shows water months (100 days). Novel adhesive may be useful many applications, including transfer, water‐based devices, repair, soft robots.

Language: Английский

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3D-printed multifunctional materials enabled by artificial-intelligence-assisted fabrication technologies

Nature Reviews Materials, Journal Year: 2020, Volume and Issue: 6(1), P. 27 - 47

Published: Oct. 12, 2020

Language: Английский

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Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue

Nature Biomedical Engineering, Journal Year: 2021, Volume and Issue: 5(10), P. 1131 - 1142

Published: Aug. 9, 2021

Language: Английский

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