Environmental influences on the pace of brain development
Nature reviews. Neuroscience,
Journal Year:
2021,
Volume and Issue:
22(6), P. 372 - 384
Published: April 28, 2021
Childhood
socio-economic
status
(SES),
a
measure
of
the
availability
material
and
social
resources,
is
one
strongest
predictors
lifelong
well-being.
Here
we
review
evidence
that
experiences
associated
with
childhood
SES
affect
not
only
outcome
but
also
pace
brain
development.
We
argue
higher
protracted
structural
development
prolonged
trajectory
functional
network
segregation,
ultimately
leading
to
more
efficient
cortical
networks
in
adulthood.
hypothesize
greater
exposure
chronic
stress
accelerates
maturation,
whereas
access
novel
positive
decelerates
maturation.
discuss
impact
variation
on
plasticity
learning.
provide
generative
theoretical
framework
catalyse
future
basic
science
translational
research
environmental
influences
Evidence
suggests
can
its
rate.
Tooley,
Bassett
Mackey
this
suggest
valence
frequency
early
interact
influence
Language: Английский
Inhibitory Interneurons Regulate Temporal Precision and Correlations in Cortical Circuits
Trends in Neurosciences,
Journal Year:
2018,
Volume and Issue:
41(10), P. 689 - 700
Published: Sept. 25, 2018
Language: Английский
Neuromodulation of Spike-Timing-Dependent Plasticity: Past, Present, and Future
Neuron,
Journal Year:
2019,
Volume and Issue:
103(4), P. 563 - 581
Published: Aug. 1, 2019
Language: Английский
Encouraging an excitable brain state: mechanisms of brain repair in stroke
Nature reviews. Neuroscience,
Journal Year:
2020,
Volume and Issue:
22(1), P. 38 - 53
Published: Nov. 12, 2020
Language: Английский
Circuitry Underlying Experience-Dependent Plasticity in the Mouse Visual System
Neuron,
Journal Year:
2020,
Volume and Issue:
106(1), P. 21 - 36
Published: April 1, 2020
Since
the
discovery
of
ocular
dominance
plasticity,
neuroscientists
have
understood
that
changes
in
visual
experience
during
a
discrete
developmental
time,
critical
period,
trigger
robust
cortex.
State-of-the-art
tools
used
to
probe
connectivity
with
cell-type-specific
resolution
expanded
understanding
circuit
underlying
experience-dependent
plasticity.
Here,
we
review
circuitry
mouse,
describing
projections
from
retina
thalamus,
between
thalamus
and
cortex,
within
We
discuss
how
development
leads
precise
identify
synaptic
loci,
which
can
be
altered
by
activity
or
experience.
Plasticity
extends
features
beyond
dominance,
involving
subcortical
cortical
regions,
connections
inhibitory
interneurons.
Experience-dependent
plasticity
contributes
alignment
networks
spanning
Disruption
this
may
underlie
aberrant
sensory
processing
some
neurodevelopmental
disorders.
Vision
is
so
inseparable
our
conception
world
"seeing
believing."
Sight
crucial
recognize
friends,
find
savory
food,
plan
movement.
While
aspects
system
form
utero,
circuits
significant
spontaneous
activity-
reorganization
early
life.
Developmental
refinement
perturbations
small
errors,
imparting
uniqueness
based
on
without
an
exhaustive
molecular
code
specifying
each
connection.
occur
at
specific
time
points.
The
best-known
sensitive
periods
(SPs)
(CPs).
SPs
are
windows
when
neuronal
exhibit
modification.
Such
easily
evoked
greater
magnitude
SP,
but
smaller
extent
other
ages.
CPs
subset
SPs,
distinguished
strict
temporal
onset
closure
fact
period
required
for
subsequent
normal
function
(Voss,
2013Voss
P.
Sensitive
deprivation.Front.
Psychol.
2013;
4:
664Crossref
PubMed
Scopus
(25)
Google
Scholar).
This
change
not
reversible
except
CP.
CP
was
described
Hubel
Wiesel.
In
binocular
responsiveness
input
deprived
eye
attenuated
weeks
monocular
deprivation
(MD).
(OD),
called
(ODP),
only
occurs
development.
Moreover,
include
reduction
acuity
eye,
amblyopia.
ODP
reversed
CP,
recovery
possible
once
closes.
Growing
evidence
suggests
entirely
extinguished
closure.
Substantial
adult
outside
activated,
often
stimulus
paradigms
distinct
those
effective
(Espinosa
Stryker,
2012Espinosa
J.S.
Stryker
M.P.
Development
primary
cortex.Neuron.
2012;
75:
230-249Abstract
Full
Text
PDF
(294)
Scholar,
Fong
et
al.,
2016Fong
M.F.
Mitchell
D.E.
Duffy
K.R.
Bear
Rapid
effects
enabled
temporary
inactivation
retinas.Proc
Natl
Acad
Sci
U
S
A.
2016;
113:
14139-14144Crossref
(14)
Hensch
Quinlan,
2018Hensch
T.K.
Quinlan
E.M.
Critical
amblyopia.Vis.
Neurosci.
2018;
35:
E014PubMed
Sato
2008Sato
M.
Distinctive
plasticity.J.
2008;
28:
10278-10286Crossref
(153)
Thus,
perhaps
more
accurately
defined
as
occurring
SP.
ambiguity
highlights
difficulty
distinguishing
especially
monitor
developed.
Different
loci
along
pathway
vary
their
sensitivity
(Kang
2013Kang
E.
Durand
S.
LeBlanc
J.J.
Chen
C.
Fagiolini
Visual
absence
experience.J.
33:
17789-17796Crossref
(42)
Scholar),
one
synapse
enduring
effect
overall
because
its
influence
downstream
synapses
irreversibly.
Homeostatic
responses
also
activated
compensate
synapse,
another
(Whitt
2014Whitt
J.L.
Petrus
Lee
H.K.
homeostatic
neocortex.Neuropharmacology.
2014;
78:
45-54Crossref
(39)
end,
indelibly
Therefore,
purpose
review,
define
window
there
response
followed
clear
diminishing
same
stimuli.
Wiesel,
has
served
model
studying
Changes
following
MD
measured
comparing
(by
single
unit
recordings,
[VEPs],
vivo
imaging)
stimulation
eye.
These
straightforward
measurements
made
canonical
experimental
system.
More
recently,
enabling
measurement
such
orientation
preference
suggest
many
show
occasionally
different
rules.
implies
traditionally
circuitry,
thalamic
relay
cells,
developmentally
regulated
unrelated
OD
shifts.
Considerable
effort
been
devoted
basis
(Fagiolini
2004Fagiolini
Fritschy
J.M.
Löw
K.
Möhler
H.
Rudolph
U.
Specific
GABAA
plasticity.Science.
2004;
303:
1681-1683Crossref
(332)
means
label,
monitor,
manipulate
these
components
independently
understand
basic
where
results
changes.
mouse
powerful
model.
Despite
zone
lower
1994Fagiolini
Pizzorusso
T.
Berardi
N.
Domenici
L.
Maffei
Functional
postnatal
rat
cortex
role
experience:
dark
rearing
deprivation.Vision
Res.
1994;
34:
709-720Crossref
(491)
mice
similar
primates
cats.
clearly
day
19
(P19)
P32
(Gordon
1996Gordon
J.A.
mouse.J.
1996;
16:
3274-3286Crossref
Mice
offer
possibility
genetic
access
neuron
populations
ODP,
including
subsets
excitatory
(Gerfen
2013Gerfen
C.R.
Paletzki
R.
Heintz
GENSAT
BAC
cre-recombinase
driver
lines
study
functional
organization
cerebral
basal
ganglia
circuits.Neuron.
80:
1368-1383Abstract
(242)
Scholar)
neurons
(Taniguchi
2011Taniguchi
He
Wu
Kim
Paik
Sugino
Kvitsiani
D.
Fu
Y.
Lu
J.
Lin
al.A
resource
Cre
targeting
GABAergic
2011;
71:
995-1013Abstract
(822)
approaches
allow
targeted
recording,
optical
manipulation
(Madisen
2012Madisen
Mao
Koch
Zhuo
Berenyi
Fujisawa
Hsu
Y.W.
Garcia
3rd,
A.J.
Gu
X.
Zanella
toolbox
Cre-dependent
optogenetic
transgenic
light-induced
activation
silencing.Nat.
15:
793-802Crossref
(616)
calcium
indicators
(Chen
2013Chen
T.W.
Wardill
T.J.
Sun
Pulver
S.R.
Renninger
S.L.
Baohan
Schreiter
E.R.
Kerr
R.A.
Orger
M.B.
Jayaraman
V.
al.Ultrasensitive
fluorescent
proteins
imaging
activity.Nature.
499:
295-300Crossref
(2349)
advances
focusing
across
species,
mechanisms
reviewed
elsewhere
(Hensch
Kiorpes,
2015Kiorpes
primates:
neural
periods.Dev.
Neurobiol.
2015;
1080-1090Crossref
refer
work
areas,
extrapolating
Studies
revealed
apply
than
simply
OD.
With
variety
manipulations
quantifying
receptive
field
(RF)
properties,
orientation,
luminance,
spatial
frequency
tuning,
findings
rules
differ
ODP.
studies
demonstrate
To
instantiated,
detailed
map
needed,
long-range
major
brain
structures
(Figures
1
2)
cell
types
3
4).
true
neocortex,
contains
types,
organized
layers,
multiple
per
layer.
A
near-complete
census
(Sugino
2019Sugino
Clark
Schulmann
Shima
Wang
Hunt
D.L.
Hooks
B.M.
Tränkner
Chandrashekar
Picard
al.Mapping
transcriptional
diversity
genetically
anatomically
brain.eLife.
2019;
8:
e38619Crossref
(3)
Tasic
2018Tasic
B.
Yao
Z.
Graybuck
L.T.
Smith
K.A.
Nguyen
T.N.
Bertagnolli
Goldy
Garren
Economo
M.N.
Viswanathan
al.Shared
transcriptomic
neocortical
areas.Nature.
563:
72-78Crossref
(167)
promises
full
range
subtypes.
provides
parts
list
local
circuit.
Given
profoundly
plasticity?
Our
aim
place
order
context,
assessing
whether
hierarchy
earlier
way
nodes
thalamocortical
(TC)
afferents
compared
intracortical
L4
L2/3.Figure
2Thalamocortical
OrganizationShow
caption(A)
includes
dorsal
ventral
subdivisions
(dLGN
vLGN,
blue
purple).
Core
shell
areas
dLGN
receive
inputs
RGC
types.
Higher-order
LP
(red).(B)
Thalamic
axons
V1
arborize
laminae.View
Large
Image
Figure
ViewerDownload
Hi-res
image
Download
(PPT)Figure
3Inhibitory
Excitatory
Local
Connectivity
CortexShow
Inhibitory
interneurons
laminar
distribution
5-HT3AR+
concentrated
L1
L2/3,
VIP+
PV+
SST+
present
all
(after
2010Lee
Hjerling-Leffler
Zagha
Fishell
G.
Rudy
largest
group
superficial
expresses
ionotropic
serotonin
receptors.J.
2010;
30:
16796-16808Crossref
(323)
Xu
2010Xu
Roby
K.D.
Callaway
Immunochemical
characterization
neurons:
three
chemically
classes
cells.J.
Comp.
Neurol.
518:
389-404Crossref
(256)
Subtypes
highlighted
table
right.(B)
bipolar
disinhibit
specifically
inhibiting
neurons.
cells
tonically
inhibit
pyramidal
(Pyr)
apical
dendrites.
Tonic
inhibition
released
become
active
(Pfeffer
2013Pfeffer
C.K.
Xue
Huang
Z.J.
Scanziani
Inhibition
cortex:
logic
molecularly
interneurons.Nat.
1068-1076Crossref
(527)
Input
VIP
(black
magenta
arrows)
areas.
L4,
less
abundant.(C
D)
Major
granular
supragranular
given
layer
nearby
layers
(Xu
2016Xu
Olivas
N.D.
Ikrar
Peng
Holmes
T.C.
Nie
Q.
Shi
Primary
shows
laminar-specific
balanced
connectivity.J.
Physiol.
594:
1891-1910Crossref
Ascending
(left)
descending
(right),
thicknesses
proportional
connection
strength.
Laminae
shown
red.
Strength
illustration
(C)
matrix
(D),
pre-
postsynaptic
labeled.(E)
L2/3
L4.View
4Developmental
Cortical
Near
Period
(CP)Show
For
illustrated.
illustrated
black.
(blue),
(burgundy),
(green)
color
coded,
neuromodulatory
acetylcholine
(purple).
TC
age
annotated
bottom.
interneuron
precede
(Jiang
2010Jiang
Sohya
Sarihi
Yanagawa
Tsumoto
Laminar-specific
maturation
transmission
susceptibility
related
endocannabinoid
cortex.J.
14261-14272Crossref
(33)
PV
correlated
matures
(Cossell
2015Cossell
Iacaruso
Muir
D.R.
Houlton
Sader
E.N.
Ko
Hofer
S.B.
Mrsic-Flogel
T.D.
strength
cortex.Nature.
399-403Crossref
(191)
2013Ko
Cossell
Baragli
Antolik
Clopath
emergence
microcircuits
496:
96-100Crossref
(198)
neurons,
initially
strong,
grows
weaker
loses
cholinergic
modulation
(Yaeger
2019Yaeger
C.E.
Ringach
Trachtenberg
J.T.
Neuromodulatory
control
localized
dendritic
spiking
567:
100-104Crossref
Scholar).(B)
Mature
summarized.View
(PPT)
(A)
(red).
(B)
laminae.
right.
abundant.
(C
labeled.
(E)
L4.
summarized.
mammals
begins
retina,
retinal
ganglion
(RGC)
target
number
superior
colliculus
(SC),
lateral
geniculate
nucleus
(dLGN),
suprachiasmatic
(SCN;
Figures
1A–1C).
Blue
red
figure
illustrate
corresponding
ipsilateral
contralateral
eyes,
eye-specific
segregation
dLGN.
projection
rounded
patch
surrounded
larger
area
input.
Some
overlap
exists
(Figure
1B;
Howarth
2014Howarth
Walmsley
Brown
T.M.
Binocular
integration
nuclei.Curr.
Biol.
24:
1241-1247Abstract
subdivided
into
core
region,
projecting
principally
4
(L4)
(V1,
VISp
reference
atlas;
Kuan
2015Kuan
Li
Lau
Feng
Bernard
Sunkin
S.M.
Zeng
Dang
Hawrylycz
Ng
Neuroinformatics
Allen
Mouse
Brain
Atlas.Methods.
73:
4-17Crossref
(72)
largely
targets
(Cruz-Martín
2014Cruz-Martín
El-Danaf
R.N.
Osakada
F.
Sriram
Dhande
O.S.
P.L.
Ghosh
Huberman
A.D.
dedicated
links
direction-selective
507:
358-361Crossref
(151)
posterior
(LP)
(similar
pulvinar
primates),
projects
strongly
L1,
deeper
L5A.
structure
output
(Bennett
2019Bennett
Gale
S.D.
Garrett
M.E.
Newton
M.L.
Murphy
G.J.
Olsen
Higher-Order
Circuits
Channel
Parallel
Streams
Information
Mice.Neuron.
102:
477-492.e5Abstract
(23)
Two
intrinsic
interneurons,
former
outnumber
latter
∼4:1.
Intrinsic
make
dendrodendritic
axodendritic
onto
(triads;
Bickford
2010Bickford
Slusarczyk
Dilger
E.K.
Krahe
T.E.
Kucuk
Guido
W.
Synaptic
nucleus.J.
622-635Crossref
(52)
Morgan
2016Morgan
Berger
Wetzel
A.W.
Lichtman
J.W.
Fuzzy
Logic
Network
Thalamus.Cell.
165:
192-206Abstract
(88)
Rafols
Valverde,
1973Rafols
Valverde
mouse.
Golgi
electron
microscopic
study.J.
1973;
150:
303-332Crossref
two
corticothalamic
(CT)
well
reticular
(TRNs).
project
sending
collaterals
TRN.
Interneurons
parvalbumin
positive
(PV+),
whereas
PV−,
although
complete
(Kalish
2018Kalish
B.T.
Cheadle
Hrvatin
Nagy
M.A.
Rivera
Crow
Gillis
Kirchner
Greenberg
Single-cell
transcriptomics
developing
reveals
insights
assembly
refinement.Proc.
Natl.
Acad.
Sci.
USA.
115:
E1051-E1060Crossref
(17)
CT
inputs,
turn,
send
TRNs.
integrates,
modifies,
relays
information
passing
V1.
Experience-Dependent
Thalamus.
cat,
much
(Wiesel
Hubel,
1963aWiesel
D.H.
striate
kittens
vision
eye.J.
Neurophysiol.
1963;
26:
1003-1017Crossref
(1751)
shrinkage
somata
dLGN,
little
(Sherman
Spear,
1982Sherman
Spear
P.D.
Organization
pathways
visually
cats.Physiol.
Rev.
1982;
62:
738-855Crossref
(493)
Wiesel
1963bWiesel
Effects
Deprivation
Morphology
Physiology
Cells
Cats
Lateral
Geniculate
Body.J.
978-993Crossref
(797)
(Guzik-Kornacka
2016Guzik-Kornacka
van
der
Bourg
Vajda
Joly
Christ
Schwab
Pernet
Nogo-A
deletion
increases
optokinetic
system.Brain
Struct.
Funct.
221:
317-329Crossref
(10)
led
view
predominantly
phenomenon.
contrast
uncovered
previously
recognized.
traditional
divides
territories,
region.
However,
recordings
dorsomedial
responsive
stimulation,
indicating
convergent
both
eyes
(Howarth
extend
dendrites
(Krahe
2011Krahe
Henderson
S.C.
Morphologically
regional
preferences
31:
17437-17448Crossref
(57)
below
(∼P18–P32)
shifts
relative
depends
receptor
α1
subunit
(Sommeijer
2017Sommeijer
J.P.
Ahmadlou
Saiepour
M.H.
Seignette
Min
Heimel
Levelt
C.N.
regulates
critical-period
thalamus.Nat.
2017;
20:
1715-1721Crossref
(15)
Future
needed
reveal
potential
onsets
opening
reversible.
Notably,
boutons
terminating
MD,
even
(Jaepel
2017Jaepel
Hübener
Bonhoeffer
Rose
mice.Nat.
1708-1714Crossref
Bonhoeffe
Language: Английский
Stress and adolescence: vulnerability and opportunity during a sensitive window of development
Current Opinion in Psychology,
Journal Year:
2021,
Volume and Issue:
44, P. 286 - 292
Published: Oct. 25, 2021
Language: Английский
Early-life adversity and neurological disease: age-old questions and novel answers
Nature Reviews Neurology,
Journal Year:
2019,
Volume and Issue:
15(11), P. 657 - 669
Published: Sept. 17, 2019
Language: Английский
All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1
Cell,
Journal Year:
2020,
Volume and Issue:
180(3), P. 521 - 535.e18
Published: Jan. 23, 2020
Language: Английский
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses
Cell Reports,
Journal Year:
2022,
Volume and Issue:
38(13), P. 110600 - 110600
Published: March 1, 2022
Several
mental
illnesses,
characterized
by
aberrant
stress
reactivity,
often
arise
after
early-life
adversity
(ELA).
However,
it
is
unclear
how
ELA
affects
stress-related
brain
circuit
maturation,
provoking
these
enduring
vulnerabilities.
We
find
that
increases
functional
excitatory
synapses
onto
stress-sensitive
hypothalamic
corticotropin-releasing
hormone
(CRH)-expressing
neurons,
resulting
from
disrupted
developmental
synapse
pruning
adjacent
microglia.
Microglial
process
dynamics
and
synaptic
element
engulfment
were
attenuated
in
mice,
associated
with
deficient
signaling
of
the
microglial
phagocytic
receptor
MerTK.
Accordingly,
selective
chronic
chemogenetic
activation
microglia
increased
reduced
density
to
control
levels.
Notably,
normalized
adult
acute
responses,
including
stress-induced
secretion
behavioral
threat
as
well
adrenal
hypertrophy
mice.
Thus,
actions
during
development
are
powerful
contributors
mechanisms
which
sculpts
connectivity
stress-regulating
promoting
vulnerability
illnesses.
Language: Английский
Cochlear neural degeneration disrupts hearing in background noise by increasing auditory cortex internal noise
Neuron,
Journal Year:
2021,
Volume and Issue:
109(6), P. 984 - 996.e4
Published: Feb. 8, 2021
Language: Английский
