Revolutionizing Medical Implant Fabrication: Advances in Additive Manufacturing of Biomedical Metals DOI Creative Commons
Yu-Hua Li, Deyu Jiang, Rui Zhu

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022002 - 022002

Published: Nov. 14, 2024

Highlights Exploring personalized biomedical metal implants through additive manufacturing (AM). Presenting new load-bearing and biodegradable alloys for implants. Showcasing AI 4D printing advancements in material properties. AM’s roles various medical fields. Highlighting perspectives of implant technology improved patient care.

Language: Английский

High-performance brain-to-text communication via handwriting DOI
Francis R. Willett, Donald T. Avansino, Leigh R. Hochberg

et al.

Nature, Journal Year: 2021, Volume and Issue: 593(7858), P. 249 - 254

Published: May 12, 2021

Language: Английский

Citations

654

Artificial Intelligence‐Enabled Sensing Technologies in the 5G/Internet of Things Era: From Virtual Reality/Augmented Reality to the Digital Twin DOI Creative Commons
Zixuan Zhang, Feng Wen, Zhongda Sun

et al.

Advanced Intelligent Systems, Journal Year: 2022, Volume and Issue: 4(7)

Published: March 29, 2022

With the development of 5G and Internet Things (IoT), era big data‐driven product design is booming. In addition, artificial intelligence (AI) also emerging evolving by recent breakthroughs in computing power software architectures. this regard, digital twin, analyzing various sensor data with help AI algorithms, has become a cutting‐edge technology that connects physical virtual worlds, which sensors are highly desirable to collect environmental information. However, although existing technologies, including cameras, microphones, inertial measurement units, etc., widely used as sensing elements for applications, high‐power consumption battery replacement them still problem. Triboelectric nanogenerators (TENGs) self‐powered supply feasible platform realizing self‐sustainable low‐power systems. Herein, progress on TENG‐based intelligent systems, is, wearable electronics, robot‐related smart homes, followed prospective future enabled fusion technology, focused on. Finally, how apply systems IoT discussed.

Language: Английский

Citations

314

A tissue-like neurotransmitter sensor for the brain and gut DOI
Jinxing Li, Yuxin Liu, Lei Yuan

et al.

Nature, Journal Year: 2022, Volume and Issue: 606(7912), P. 94 - 101

Published: June 1, 2022

Language: Английский

Citations

310

A high-performance speech neuroprosthesis DOI Creative Commons
Francis R. Willett, Erin M. Kunz, Chaofei Fan

et al.

Nature, Journal Year: 2023, Volume and Issue: 620(7976), P. 1031 - 1036

Published: Aug. 23, 2023

Speech brain-computer interfaces (BCIs) have the potential to restore rapid communication people with paralysis by decoding neural activity evoked attempted speech into text

Language: Английский

Citations

244

Pushing the frontiers: tools for monitoring neurotransmitters and neuromodulators DOI
Zhaofa Wu, Dayu Lin, Yulong Li

et al.

Nature reviews. Neuroscience, Journal Year: 2022, Volume and Issue: 23(5), P. 257 - 274

Published: March 31, 2022

Language: Английский

Citations

163

Bioadhesive and conductive hydrogel-integrated brain-machine interfaces for conformal and immune-evasive contact with brain tissue DOI Creative Commons
Xiao Wang, Xiaotong Sun, Donglin Gan

et al.

Matter, Journal Year: 2022, Volume and Issue: 5(4), P. 1204 - 1223

Published: Jan. 31, 2022

Language: Английский

Citations

121

A Nonswelling Hydrogel with Regenerable High Wet Tissue Adhesion for Bioelectronics DOI
Gongwei Tian, Dan Yang,

Cuiyuan Liang

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(18)

Published: Feb. 5, 2023

Reducing the swelling of tissue-adhesive hydrogels is crucial for maintaining stable tissue adhesion and inhibiting inflammation. However, reported strategies reducing always result in a simultaneous decrease adhesive strength hydrogel. Furthermore, once covalent bonds break currently hydrogels, they cannot be rebuilt, hydrogel loses its ability. In this work, nonswelling (named as "PAACP") possessing regenerable high synthesized by copolymerizing crosslinking poly(vinyl butyral) with acrylic acid, gelatin, chitosan-grafted N-acetyl-l-cysteine. The obtained PAACP reaches 211.4 kPa, which approximately ten times higher than that can reused multiple cycles. as-prepared shows great potential soft bioelectronics, muscle fatigue successfully monitored via electrode array strain sensor integrated on substrates. success these bioelectronics offers applicability long-term diagnosis muscle-related health conditions prosthetic manipulations.

Language: Английский

Citations

121

Optophysiology: Illuminating cell physiology with optogenetics DOI Creative Commons
Peng Tan, Lian He, Yun Huang

et al.

Physiological Reviews, Journal Year: 2022, Volume and Issue: 102(3), P. 1263 - 1325

Published: Jan. 24, 2022

Optogenetics combines light and genetics to enable precise control of living cells, tissues, organisms with tailored functions. has the advantages noninvasiveness, rapid responsiveness, tunable reversibility, superior spatiotemporal resolution. Following initial discovery microbial opsins as light-actuated ion channels, a plethora naturally occurring or engineered photoreceptors photosensitive domains that respond at varying wavelengths ushered in next chapter optogenetics. Through protein engineering synthetic biology approaches, genetically encoded photoswitches can be modularly into scaffolds host cells myriad biological processes, well behavioral disease intervention vivo. Here, we summarize these optogenetic tools on basis their fundamental photochemical properties better inform chemical design principles. We also highlight exemplary applications opsin-free optogenetics dissecting cellular physiology (designated "optophysiology") describe current progress, future trends, wireless optogenetics, which enables remote interrogation physiological processes minimal invasiveness. This review is anticipated spark novel thoughts next-generation devices promise accelerate both basic translational studies.

Language: Английский

Citations

82

Remote control of muscle-driven miniature robots with battery-free wireless optoelectronics DOI
Yongdeok Kim, Yiyuan Yang, Xiaotian Zhang

et al.

Science Robotics, Journal Year: 2023, Volume and Issue: 8(74)

Published: Jan. 18, 2023

Bioengineering approaches that combine living cellular components with three-dimensional scaffolds to generate motion can be used develop a new generation of miniature robots. Integrating on-board electronics and remote control in these biological machines will enable various applications across engineering, biology, medicine. Here, we present hybrid bioelectronic robots equipped battery-free microinorganic light-emitting diodes for wireless real-time communication. Centimeter-scale walking were computationally designed optimized host optoelectronics independent stimulation multiple optogenetic skeletal muscles, achieving command walking, turning, plowing, transport functions both at individual collective levels. This work paves the way toward class biohybrid able actuation sensing computing.

Language: Английский

Citations

59

Advanced Energy Harvesters and Energy Storage for Powering Wearable and Implantable Medical Devices DOI Creative Commons
Ziyan Gao, Yang Zhou, Jin Zhang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: June 27, 2024

Wearable and implantable active medical devices (WIMDs) are transformative solutions for improving healthcare, offering continuous health monitoring, early disease detection, targeted treatments, personalized medicine, connected capabilities. Commercialized WIMDs use primary or rechargeable batteries to power their sensing, actuation, stimulation, communication functions, periodic battery replacements of implanted pose major risks surgical infections inconvenience users. Addressing the energy source challenge is critical meeting growing demand WIMD market that reaching valuations in tens billions dollars. This review critically assesses recent advances harvesting storage technologies can potentially eliminate need replacements. With a key focus on advanced materials enable harvesters meet needs WIMDs, this examines crucial roles efficiencies harvesters, wireless charging, devices. concludes by highlighting challenges opportunities necessary achieve vision self-powered wearable devices, eliminating associated with replacement frequent manual recharging.

Language: Английский

Citations

38