The chemosensory protein 1 contributes to indoxacarb resistance in Plutella xylostella(L.) DOI
Yifan Li,

Shujun Ni,

Yunping Wang

et al.

Pest Management Science, Journal Year: 2023, Volume and Issue: 79(7), P. 2456 - 2468

Published: Feb. 21, 2023

Insecticide resistance continuously poses a threat to agricultural production. Chemosensory protein-mediated is new mechanism of insecticide discovered in recent years. In-depth research on mediated by chemosensory proteins (CSPs) provides insight into aid management.Chemosensory protein 1 Plutella xylostella (PxCSP1) was overexpressed the two indoxacarb-resistant field populations and PxCSP1 has high affinity with indoxacarb. upregulated when exposed indoxacarb knockdown this gene elevated sensitivity indoxacarb, which demonstrate that involved resistance. Considering CSPs may confer insects via binding or sequestering, we explored PxCSP1-mediated Using molecular dynamics simulations site-directed mutation, found forms solid complex mainly through van der Waals interactions electrostatic interactions. Between these, interaction provided Lys100 side chain PxCSP1, especially hydrogen bonding between NZ atom O carbamoyl carbonyl group are key factors for indoxacarb.The overexpression PxCPS1 its partially responsible P. xylostella. Modification indoxacarb's potential alleviate These findings will contribute solving provide better understanding mechanism. © 2023 Society Chemical Industry.

Language: Английский

A review of the molecular mechanisms of acaricide resistance in mites and ticks DOI Creative Commons
Sander De Rouck, Emre İnak, Wannes Dermauw

et al.

Insect Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 159, P. 103981 - 103981

Published: June 28, 2023

The Arachnida subclass of Acari comprises many harmful pests that threaten agriculture as well animal health, including herbivorous spider mites, the bee parasite Varroa, poultry mite Dermanyssus and several species ticks. Especially in agriculture, acaricides are often used intensively to minimize damage they inflict, promoting development resistance. Beneficial predatory mites biological control also subjected acaricide selection field. use new genetic genomic tools such genome transcriptome sequencing, bulked segregant analysis (QTL mapping), reverse genetics via RNAi or CRISPR/Cas9, have greatly increased our understanding molecular mechanisms resistance Acari, especially Tetranychus urticae which emerged a model species. These techniques allowed uncover validate mutations larger range In addition, provided an impetus start elucidating more challenging questions on gene regulation detoxification associated with

Language: Английский

Citations

86
The molecular mechanisms of insecticide resistance in aphid crop pests DOI Creative Commons
Chris Bass, Ralf Nauen

Insect Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 156, P. 103937 - 103937

Published: April 5, 2023

Aphids are a group of hemipteran insects that include some the world's most economically important agricultural pests. The control pest aphids has relied heavily on use chemical insecticides, however, evolution resistance poses serious threat to their sustainable control. Over 1000 cases have now been documented for involving remarkable diversity mechanisms that, individually or in combination, allow toxic effect insecticides be avoided overcome. In addition its applied importance as growing human food security, insecticide also offers an exceptional opportunity study under strong selection and gain insight into genetic variation fuelling rapid adaptation. this review we summarise biochemical molecular underlying aphid pests worldwide insights topic provided genomic architecture adaptive traits.

Language: Английский

Citations

60
Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus persicae DOI Creative Commons
Adam Pym, Paul A. Umina,

Jenny Reidy‐Crofts

et al.

Insect Biochemistry and Molecular Biology, Journal Year: 2022, Volume and Issue: 143, P. 103743 - 103743

Published: Feb. 22, 2022

The green peach aphid, Myzus persicae, is a highly damaging, globally distributed crop pest that has evolved multiple resistance to numerous insecticides. It thus imperative insecticides are not strongly compromised by pre-existing carefully managed maximise their effective life span. Sulfoxaflor sulfoximine insecticide retains efficacy against M. persicae clones exhibit older In the current study we monitored of sulfoxaflor populations collected in Western Australia, following reports control failures this region. We identified with low (4-23-fold across independent bioassay experiments), but significant, levels compared reference susceptible clone. Furthermore, demonstrate can persist after many months culturing laboratory absence exposure. Resistance was conferred known mechanisms neonicotinoid insecticides, act on same target-site as sulfoxaflor, i.e. R81T mutation or overexpresssion P450 gene CYP6CY3. Rather, transcriptome profiling resistant and CYP380C40 UDP-glucuronosyltransferase UGT344P2 overexpressed (21-76-fold 6-33-fold respectively) clones. Transgenic expression these genes demonstrated they confer, low, vivo. Taken together, our data reveal presence low-level Australia uncover two novel conferring compound. findings tools generated provide platform for development strategies aim slow, prevent overcome evolution more potent sulfoxaflor.

Language: Английский

Citations

47
Peach–Potato Aphid Myzus persicae: Current Management Strategies, Challenges, and Proposed Solutions DOI Open Access
Jamin Ali, Ahmet Bayram, Mohammad Mukarram

et al.

Sustainability, Journal Year: 2023, Volume and Issue: 15(14), P. 11150 - 11150

Published: July 17, 2023

The peach–potato aphid, Myzus persicae (Sulzer), is one of the most important pests economic crops. It damages plant directly by consuming nutrients and water indirectly transmitting viruses. This pest has unenviable title having resistance to more insecticides than any other herbivorous insect pest. Due development its chemical pesticides, it necessary find control options. Consequently, increased efforts worldwide have been undertaken develop new management approaches for M. persicae. In this review, we highlight problems associated with importance, current approaches. review also describes challenges their potential solutions, special focus given evolution insecticidal sustainable strategies, such as biocontrol agents, entomopathogens, use natural plant-derived compounds, cultural methods. Furthermore, provides some successful from above eco-friendly strategies that show high efficacy against

Language: Английский

Citations

28
Spirotetramat resistance inMyzus persicae(Sulzer) (Hemiptera: Aphididae) and its association with the presence of theA2666Vmutation DOI Creative Commons
Paul A. Umina, Chris Bass, Anthony van Rooyen

et al.

Pest Management Science, Journal Year: 2022, Volume and Issue: 78(11), P. 4822 - 4831

Published: July 28, 2022

Abstract BACKGROUND Chemicals are widely used to protect field crops against aphid pests and aphid‐borne viral diseases. One such species is Myzus persicae (Sulzer), a global pest that attacks broad array of agricultural transmits many economically damaging plant viruses. This has evolved resistance large number insecticide compounds as result widespread repeated chemical use in parts the world. In this study, we investigated evolution new protection product, spirotetramat, following reported control failures. RESULTS Our study provides clear phenotypic genotypic evidence spirotetramat populations M. from Australia. We show there cross‐resistance other insecticides within same group, namely spiromesifen spirodiclofen. also demonstrate associated with previously mutation, A2226V target site acetyl‐CoA carboxylase. genetic analysis found all resistant belong multi‐locus clonal type carry which appears be inherited dominant trait species. CONCLUSION findings provide insight into conferred by have implications for Australia worldwide. A diagnostic assay developed should serve valuable tool future monitoring support implementation management strategies. © 2022 The Authors. Pest Management Science published John Wiley & Sons Ltd on behalf Society Chemical Industry.

Language: Английский

Citations

33
Molecular Mechanisms Underlying Host Plant Specificity in Aphids DOI Creative Commons
Po‐Yuan Shih, Akiko Sugio, Jean‐Christophe Simon

et al.

Annual Review of Entomology, Journal Year: 2022, Volume and Issue: 68(1), P. 431 - 450

Published: Oct. 13, 2022

Aphids are serious pests of agricultural and ornamental plants important model systems for hemipteran-plant interactions. The long evolutionary history aphids with their host has resulted in a variety that provide insight into the different adaptation strategies to vice versa. In past, various plant-aphid interactions have been documented, but lack functional tools limited molecular studies on mechanisms Recent technological advances begun reveal at level increase our knowledge aphid or specialization plants. this article, we compile analyze available information interactions, discuss limitations current knowledge, argue new research directions. We advocate more work takes advantage natural recently established techniques obtain comprehensive view interaction mechanisms.

Language: Английский

Citations

32
Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators DOI
Mark Montgomery,

Stefano Rendine,

Christoph T. Zimmer

et al.

Journal of Medicinal Chemistry, Journal Year: 2022, Volume and Issue: 65(3), P. 2297 - 2312

Published: Jan. 5, 2022

The development of novel and safe insecticides remains an important need for a growing world population to protect crops animal human health. New chemotypes modulating the insect nicotinic acetylcholine receptors have been recently brought agricultural market, yet with limited understanding their molecular interactions at target receptor. Herein, we disclose first crystal structures these insecticides, namely, sulfoxaflor, flupyradifurone, triflumezopyrim, flupyrimin, experimental compound, dicloromezotiaz, in double-mutated acetylcholine-binding protein which mimics insect-ion-channel orthosteric site. Enabled by findings, discovered pharmacophores related mode action, describe herein design, synthesis, biological evaluation.

Language: Английский

Citations

28
Population Genomics for Insect Conservation DOI Creative Commons
Matthew T. Webster, Alexis Beaurepaire, Peter Neumann

et al.

Annual Review of Animal Biosciences, Journal Year: 2022, Volume and Issue: 11(1), P. 115 - 140

Published: Nov. 14, 2022

Insects constitute vital components of ecosystems. There is alarming evidence for global declines in insect species diversity, abundance, and biomass caused by anthropogenic drivers such as habitat degradation or loss, agricultural practices, climate change, environmental pollution. This raises important concerns about human food security ecosystem functionality calls more research to assess population trends identify threatened the causes inform conservation strategies. Analysis genetic diversity a powerful tool address these goals, but so far animal genetics has focused strongly on endangered vertebrates, devoting less attention invertebrates, insects, that most biodiversity. Insects' shorter generation times larger sizes likely necessitate different analytical methods management The availability high-quality reference genome assemblies enables genomics several key issues. These include precise inference past demographic fluctuations recent declines, measurement load levels, delineation evolutionarily significant units cryptic species, analysis adaptation stressors. identification populations are particularly vulnerable future threats, considering their potential adapt evolve. We review application outlook averting declines.

Language: Английский

Citations

27
Diversity and Regional Variation of Endosymbionts in the Green Peach Aphid, Myzus persicae (Sulzer) DOI Creative Commons
Qiong Yang, Paul A. Umina, Shu‐Jun Wei

et al.

Diversity, Journal Year: 2023, Volume and Issue: 15(2), P. 206 - 206

Published: Feb. 1, 2023

The green peach aphid, Myzus persicae, is globally distributed and an important pest of many economically valuable food crops, largely due to its ability transmit plant viruses. Almost all aphids, including M. carry the obligate symbiont Buchnera aphidicola, which provides essential amino acids that aphids cannot obtain from phloem plants themselves. Many also harbor facultative (secondary) endosymbionts, provide benefits under specific ecological conditions. In this study, we screened for secondary endosymbionts in with a particular focus on Australian populations where species growing status as major agricultural pest. We compared 37 persicae other populations, 21 field China 15 clones UK, France, Italy, Greece, USA, Spain, South Korea, Chile, Japan Zimbabwe. No were identified samples outside China, despite covering wide geographic range being collected several host families. detected two (Rickettsia, Spiroplasma) Chinese samples, although diversity appeared lower than recent study. found very high clonal based DNA microsatellite markers comparison Australia. These patterns may indicate higher (and diversity) native when invasive range.

Language: Английский

Citations

14
Virus Diseases of Cereal and Oilseed Crops in Australia: Current Position and Future Challenges DOI Creative Commons
Richard A. Jones, Murray Sharman, Piotr Trębicki

et al.

Viruses, Journal Year: 2021, Volume and Issue: 13(10), P. 2051 - 2051

Published: Oct. 12, 2021

This review summarizes research on virus diseases of cereals and oilseeds in Australia since the 1950s. All viruses known to infect diverse range cereal oilseed crops grown continent’s temperate, Mediterranean, subtropical tropical cropping regions are included. Viruses that occur commonly have potential cause greatest seed yield quality losses described detail, focusing their biology, epidemiology management. These are: barley yellow dwarf virus, wheat streak mosaic wheat, barley, oats, triticale rye; Johnsongrass sorghum, maize, sweet corn pearl millet; turnip yellows canola Indian mustard; tobacco sunflower; cotton bunchy top cotton. The currently less important covered number nine infecting 14 eight (none recorded for rice or linseed). Brief background information scope Australian industries, management loss quantification is provided. Major future threats managing effectively include damaging vector species spreading from elsewhere, increasing spectrum insecticide resistance insect mite vectors, resistance-breaking strains, changes epidemiology, vectors impacts arising climate instability extreme weather events, insufficient industry awareness diseases. pressing need more resources focus addressing these emphasized recommendations over priorities

Language: Английский

Citations

31