Small Methods,
Journal Year:
2023,
Volume and Issue:
8(3)
Published: Nov. 27, 2023
Abstract
3D
printing
is
now
recognized
as
a
significant
tool
for
medical
research
and
clinical
practice,
leading
to
the
emergence
of
technology.
It
essential
improve
properties
3D‐printed
products
meet
demand
use.
The
core
generating
qualified
develop
advanced
materials
processes.
Taking
advantage
nanomaterials
with
tunable
distinct
physical,
chemical,
biological
properties,
integrating
nanotechnology
into
creates
new
opportunities
advancing
field.
Recently,
some
attempts
are
made
through
nanotechnology,
providing
insights
developing
With
high‐resolution
technology,
nano‐structures
can
be
directly
fabricated
applications.
Incorporating
material
system
products.
At
same
time,
used
expand
novel
technologies.
This
review
introduced
strategies
progresses
improving
discussed
challenges
in
translation.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(8), P. 4086 - 4153
Published: Jan. 1, 2024
This
review
critically
analyzes
degradable
biomedical
elastomers,
focusing
on
their
degradation,
synthesis,
microstructure,
and
role
in
tissue
repair.
It
guides
experts
balancing
degradation
with
repair
for
improved
applications.
Science,
Journal Year:
2024,
Volume and Issue:
385(6708), P. 566 - 572
Published: Aug. 1, 2024
Incorporation
of
polymer
chain
entanglements
within
a
single
network
can
synergistically
improve
stiffness
and
toughness,
yet
attaining
such
dense
through
vat
photopolymerization
additive
manufacturing
[e.g.,
digital
light
processing
(DLP)]
remains
elusive.
We
report
facile
strategy
that
combines
dark
polymerization
to
allow
constituent
chains
densely
entangle
as
they
form
printed
structures.
This
generalizable
approach
reaches
high
monomer
conversion
at
room
temperature
without
the
need
for
additional
stimuli,
or
heat
after
printing,
enables
highly
entangled
hydrogels
elastomers
exhibit
fourfold-
sevenfold-higher
extension
energies
in
comparison
traditional
DLP.
used
this
method
print
high-resolution
multimaterial
structures
with
features
spatially
programmed
adhesion
wet
tissues.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(32)
Published: April 8, 2024
Abstract
The
challenges
of
replicating
the
complex
mechanical
and
structural
diversity
natural
tissues
in
vitro
by
leveraging
multi‐material
digital
light
processing
(DLP)
bioprinting
are
addressed.
This
technique
utilizes
PEGDA‐AAm
bio‐ink
to
develop
multi‐component,
cell‐laden
hydrogel
constructs
with
varying
moduli.
These
not
only
possess
heterogeneous
properties
but
also
feature
architectures
precisely
engineered
surface
microstructures.
microfluidic
chips
successfully
fabricated
perfusable
microchannels,
embedding
various
cell
types
within
matrix.
approach
enables
intricate
structures
unique
topologies,
such
as
spiral
grooves
triply
periodic
minimal
surfaces
(TPMS),
which
effectively
influence
alignment,
spreading,
migration.
By
integrating
PA
hydrogels,
diverse
moduli
biological
tissues,
including
bone,
liver
lobules,
vascular
networks
replicated.
ensures
high‐fidelity
differentiation
between
regions.
findings
provide
valuable
insights
into
impact
substrate
modulus
structure
on
behavior,
underscoring
potential
multi‐modulus
creating
sophisticated
custom‐tailored
properties.
study
significantly
advances
field
demonstrating
feasibility
effectiveness
DLP
developing
complex,
functionally
relevant
tissue
models
for
engineering
regenerative
medicine.
Journal of Tissue Engineering,
Journal Year:
2025,
Volume and Issue:
16
Published: Jan. 1, 2025
The
field
of
three
dimensional
(3D)
bioprinting
has
witnessed
significant
advancements,
with
bioinks
playing
a
crucial
role
in
enabling
the
fabrication
complex
tissue
constructs.
This
review
explores
innovative
that
are
currently
shaping
future
3D
bioprinting,
focusing
on
their
composition,
functionality,
and
potential
for
engineering,
drug
delivery,
regenerative
medicine.
development
bioinks,
incorporating
natural
synthetic
materials,
offers
unprecedented
opportunities
personalized
However,
rapid
technological
progress
raises
regulatory
challenges
regarding
safety,
standardization,
long-term
biocompatibility.
paper
addresses
these
challenges,
examining
current
frameworks
need
updated
guidelines
to
ensure
patient
safety
product
efficacy.
By
highlighting
both
hurdles,
this
comprehensive
overview
landscape
emphasizing
necessity
cross-disciplinary
collaboration
between
scientists,
clinicians,
bodies
achieve
successful
clinical
applications.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(19), P. 3940 - 3940
Published: Sept. 29, 2023
Vat
photopolymerization
(VP),
including
stereolithography
(SLA),
digital
light
processing
(DLP),
and
volumetric
printing,
employs
UV
or
visible
to
solidify
cell-laden
photoactive
bioresin
contained
within
a
vat
in
point-by-point,
layer-by-layer,
manner.
VP-based
bioprinting
has
garnered
substantial
attention
both
academia
industry
due
its
unprecedented
control
over
printing
resolution
accuracy,
as
well
rapid
speed.
It
holds
tremendous
potential
for
the
fabrication
of
tissue-
organ-like
structures
field
regenerative
medicine.
This
review
summarizes
recent
progress
VP
fields
tissue
engineering
First,
it
introduces
mechanism
photopolymerization,
followed
by
an
explanation
technique
commonly
used
biomaterials.
Furthermore,
application
was
discussed.
Finally,
challenges
facing
are
discussed,
future
trends
projected.
Biofabrication,
Journal Year:
2023,
Volume and Issue:
16(1), P. 012004 - 012004
Published: Nov. 3, 2023
The
three-dimensional
(3D)
bioprinting
technologies
are
suitable
for
biomedical
applications
owing
to
their
ability
manufacture
complex
and
high-precision
tissue
constructs.
However,
the
slow
printing
speed
of
current
layer-by-layer
(bio)printing
modality
is
major
limitation
in
biofabrication
field.
To
overcome
this
issue,
volumetric
(VBP)
developed.
VBP
changes
layer-wise
operation
conventional
devices,
permitting
creation
geometrically
complex,
centimeter-scale
constructs
tens
seconds.
next
step
onward
from
sequential
methods,
opening
new
avenues
fast
additive
manufacturing
fields
engineering,
regenerative
medicine,
personalized
drug
testing,
soft
robotics,
etc.
Therefore,
review
introduces
principles
hardware
designs
VBP-based
techniques;
then
focuses
on
recent
advances
(bio)inks
applications.
Lastly,
limitations
discussed
together
with
future
direction
research.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Aug. 21, 2024
Bone
defects
pose
significant
challenges
in
healthcare,
with
over
2
million
bone
repair
surgeries
performed
globally
each
year.
As
a
burgeoning
force
the
field
of
tissue
engineering,
3D
printing
offers
novel
solutions
to
traditional
transplantation
procedures.
However,
current
3D-printed
scaffolds
still
face
three
critical
material
selection,
methods,
cellular
self-organization
and
co-culture,
significantly
impeding
their
clinical
application.
In
this
comprehensive
review,
we
delve
into
performance
criteria
that
ideal
should
possess,
particular
focus
on
core
faced
by
technology
during
translation.
We
summarize
latest
advancements
non-traditional
materials
advanced
techniques,
emphasizing
importance
integrating
organ-like
technologies
bioprinting.
This
combined
approach
enables
more
precise
simulation
natural
structure
function.
Our
aim
writing
review
is
propose
effective
strategies
address
these
promote
translation
for
defect
treatment.
