Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications

Chemical Reviews, Journal Year: 2019, Volume and Issue: 119(8), P. 5298 - 5415

Published: March 27, 2019

Electrospinning is a versatile and viable technique for generating ultrathin fibers. Remarkable progress has been made with regard to the development of electrospinning methods engineering electrospun nanofibers suit or enable various applications. We aim provide comprehensive overview electrospinning, including principle, methods, materials, begin brief introduction early history followed by discussion its principle typical apparatus. then discuss renaissance over past two decades as powerful technology production diversified compositions, structures, properties. Afterward, we applications nanofibers, their use "smart" mats, filtration membranes, catalytic supports, energy harvesting/conversion/storage components, photonic electronic devices, well biomedical scaffolds. highlight most relevant recent advances related focusing on representative examples. also offer perspectives challenges, opportunities, new directions future development. At end, approaches scale-up briefly types commercial products based that have found widespread in our everyday life.

Language: Английский

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Supramolecular Luminescent Sensors

Chemical Reviews, Journal Year: 2018, Volume and Issue: 119(1), P. 322 - 477

Published: Dec. 3, 2018

There is great need for stand-alone luminescence-based chemosensors that exemplify selectivity, sensitivity, and applicability overcome the challenges arise from complex, real-world media. Discussed herein are recent developments toward these goals in field of supramolecular luminescent chemosensors, including macrocycles, polymers, nanomaterials. Specific focus placed on development new macrocycle hosts since 2010, coupled with considerations underlying principles chemistry as well analytes interest common luminophores. State-of-the-art fields polymer nanomaterial sensors also examined, some remaining unsolved area discussed.

Language: Английский

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Responsive and Synergistic Antibacterial Coatings: Fighting against Bacteria in a Smart and Effective Way

Advanced Healthcare Materials, Journal Year: 2019, Volume and Issue: 8(3)

Published: Jan. 4, 2019

Abstract Antibacterial coatings that eliminate initial bacterial attachment and prevent subsequent biofilm formation are essential in a number of applications, especially implanted medical devices. Although various approaches, including bacteria‐repelling bacteria‐killing mechanisms, have been developed, none them entirely successful due to their inherent drawbacks. In recent years, antibacterial responsive the microenvironment, possess two or more killing triggered‐cleaning capability emerged as promising solutions for infection contamination problems. This review focuses on progress three types such synergistic coatings, i) self‐defensive which can “turn on” biocidal activity response bacteria‐containing microenvironment; ii) mechanisms interact synergistically reinforce each other; iii) smart “kill‐and‐release” switch functionality between bacteria releasing under proper stimulus. The design principles potential applications these discussed brief perspective remaining challenges future research directions is presented.

Language: Английский

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Advances in controlled release pesticide formulations: Prospects to safer integrated pest management and sustainable agriculture

Journal of Hazardous Materials, Journal Year: 2019, Volume and Issue: 385, P. 121525 - 121525

Published: Nov. 2, 2019

Language: Английский

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Stimuli‐Responsive Nanocomposite Hydrogels for Biomedical Applications

Advanced Functional Materials, Journal Year: 2020, Volume and Issue: 31(8)

Published: Nov. 18, 2020

Abstract The complex tissue‐specific physiology that is orchestrated from the nano‐ to macroscale, in conjugation with dynamic biophysical/biochemical stimuli underlying biological processes, has inspired design of sophisticated hydrogels and nanoparticle systems exhibiting stimuli‐responsive features. Recently, nanoparticles have been combined advanced nanocomposite hybrid platforms expanding their range biomedical applications. ease flexibility attaining modular hydrogel constructs by selecting different classes nanomaterials/hydrogels, or tuning nanoparticle‐hydrogel physicochemical interactions widely expands attainable properties levels beyond those traditional platforms. This review showcases intrinsic ability react external internal/physiological scope developing intelligent application‐oriented Moreover, are overviewed context encoding cascades recapitulate signaling interplays present native biosystems. Collectively, recent breakthroughs improve potential for operating as applications benefit tailored single multi‐responsiveness.

Language: Английский

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Smart nanoparticles for cancer therapy

Signal Transduction and Targeted Therapy, Journal Year: 2023, Volume and Issue: 8(1)

Published: Nov. 3, 2023

Abstract Smart nanoparticles, which can respond to biological cues or be guided by them, are emerging as a promising drug delivery platform for precise cancer treatment. The field of oncology, nanotechnology, and biomedicine has witnessed rapid progress, leading innovative developments in smart nanoparticles safer more effective therapy. In this review, we will highlight recent advancements including polymeric dendrimers, micelles, liposomes, protein cell membrane mesoporous silica gold iron oxide quantum dots, carbon nanotubes, black phosphorus, MOF others. We focus on their classification, structures, synthesis, intelligent features. These possess the ability various external internal stimuli, such enzymes, pH, temperature, optics, magnetism, making them systems. Additionally, review explore latest studies tumor targeting functionalizing surfaces with tumor-specific ligands like antibodies, peptides, transferrin, folic acid. also summarize different types options, small molecules, proteins, nucleic acids, even living cells, potential use While is promising, acknowledge challenges clinical prospects associated use. Finally, propose blueprint that involves artificial intelligence-powered treatment applications. By harnessing aims usher new era personalized therapy, providing patients individualized options.

Language: Английский

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Smart Antibacterial Surfaces with Switchable Bacteria-Killing and Bacteria-Releasing Capabilities

ACS Applied Materials & Interfaces, Journal Year: 2017, Volume and Issue: 9(43), P. 37511 - 37523

Published: Oct. 9, 2017

The attachment and subsequent colonization of bacteria on the surfaces synthetic materials devices lead to serious problems in both human healthcare industrial applications. Therefore, antibacterial that can prevent bacterial biofilm formation have been a long-standing focus considerable interest research efforts. Recently, promising "kill-release" strategy has proposed applied construct so-called smart surfaces, which kill attached their surface then undergo on-demand release dead other debris reveal clean under an appropriate stimulus, thereby maintaining effective long-term activity. This Review focuses recent progress (particularly over past 5 years) such surfaces. According different design strategies, these be divided into three categories: (i) "K + R"-type killing unit releasing unit; (ii) → surface-immobilized switched perform function; (iii) (R)"-type only but upon addition solution. In end, brief perspective future directions major challenges this field is also presented.

Language: Английский

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Bioinspired Stimuli‐Responsive Color‐Changing Systems

Advanced Materials, Journal Year: 2018, Volume and Issue: 30(19)

Published: April 26, 2018

Abstract Stimuli‐responsive colors are a unique characteristic of certain animals, evolved as either method to hide from enemies and prey or communicate their presence rivals mates. From material science perspective, the solutions developed by Mother Nature achieve these effects source inspiration scientists for decades. Here, an updated overview literature on bioinspired stimuli‐responsive color‐changing systems is provided. Starting natural systems, which inspiration, classification different proposed given, based stimuli used trigger effect.

Language: Английский

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Customizing poly(lactic-co-glycolic acid) particles for biomedical applications

Acta Biomaterialia, Journal Year: 2018, Volume and Issue: 73, P. 38 - 51

Published: April 11, 2018

Nano- and microparticles have increasingly widespread applications in nanomedicine, ranging from drug delivery to imaging. Poly(lactic-co-glycolic acid) (PLGA) particles are the most widely-applied type of due their biocompatibility biodegradability. Here, we discuss preparation PLGA particles, various modifications tailor for biological systems. We highlight new approaches, including microfluidics PRINT method, resulting novel or responsive properties, such as Janus upconversion particles. Finally, describe how methods can- should-be adapted properties desired biomedical application. Our aim is enable researchers who work with better appreciate effects selected procedure on final its implications.Nanoparticles important field biomedicine. Particles made polymers spotlight, biodegradability, biocompatibility, versatility. In this review, range formulation techniques, manipulations, poly(lactic-co-glycolic a researcher effectively select design optimal techniques particle synthesis impact possible applications. focus recent developments that emerged over past years. Overall, show chemistry can be solve pressing needs.

Language: Английский

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Development of stimuli-responsive nano-based pesticides: emerging opportunities for agriculture

Journal of Nanobiotechnology, Journal Year: 2019, Volume and Issue: 17(1)

Published: Sept. 21, 2019

Abstract Pesticides and fertilizers are widely used to enhance agriculture yields, although the fraction of pesticides applied in field that reaches targets is less than 0.1%. Such indiscriminate use chemical disadvantageous due cost implications increasing human health environmental concerns. In recent years, utilization nanotechnology create novel formulations has shown great potential for diminishing providing environmentally safer alternatives. Smart nano-based designed efficiently delivery sufficient amounts active ingredients response biotic and/or abiotic stressors act as triggers, employing targeted controlled release mechanisms. This review discusses current status stimuli-responsive systems with be agriculture, highlighting challenges drawbacks need overcome order accelerate global commercialization smart nanopesticides.

Language: Английский

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