Materials,
Journal Year:
2021,
Volume and Issue:
14(10), P. 2647 - 2647
Published: May 18, 2021
Porous
tantalum
(Ta)
is
a
promising
biomaterial
and
has
been
applied
in
orthopedics
dentistry
for
nearly
two
decades.
The
high
porosity
interconnected
pore
structure
of
porous
Ta
promise
fine
bone
ingrowth
new
formation
within
the
inner
space,
which
further
guarantee
rapid
osteointegration
bone-implant
stability
long
term.
wettability
surface
energy
that
can
facilitate
adherence,
proliferation
mineralization
osteoblasts.
Meanwhile,
low
elastic
modulus
friction
coefficient
allow
it
to
effectively
avoid
stress
shield
effect,
minimize
marginal
loss
ensure
primary
stability.
Accordingly,
satisfactory
clinical
application
Ta-based
implants
or
prostheses
mainly
derived
from
its
excellent
biological
mechanical
properties.
With
advent
additive
manufacturing,
personalized
have
shown
their
value
treatment
individual
patients
who
need
specially
designed
prosthesis.
In
addition,
many
modification
methods
introduced
enhance
bioactivity
antibacterial
property
with
vitro
vivo
research
results.
any
case,
choosing
suitable
great
importance
surgical
success
after
insertion.
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(7), P. e17718 - e17718
Published: June 30, 2023
With
the
ability
to
produce
components
with
complex
and
precise
structures,
additive
manufacturing
or
3D
printing
techniques
are
now
widely
applied
in
both
industry
consumer
markets.
The
emergence
of
tissue
engineering
has
facilitated
application
field
biomedical
implants.
printed
implants
proper
structural
design
can
not
only
eliminate
stress
shielding
effect
but
also
improve
vivo
biocompatibility
functionality.
By
combining
medical
images
derived
from
technologies
such
as
X-ray
scanning,
CT,
MRI,
ultrasonic
be
used
create
patient-specific
almost
same
anatomical
structures
injured
tissues.
Numerous
clinical
trials
have
already
been
conducted
customized
However,
limited
availability
raw
materials
for
a
lack
guidance
related
regulations
laws
may
impede
development
This
review
provides
information
on
current
state
orthopedic
implant
applications.
challenges
future
perspectives
included.
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials,
Journal Year:
2019,
Volume and Issue:
102, P. 103517 - 103517
Advanced Healthcare Materials,
Journal Year:
2018,
Volume and Issue:
8(1)
Published: Dec. 7, 2018
The
successful
regeneration
of
functional
bone
tissue
in
critical-size
defects
remains
a
significant
clinical
challenge.
To
address
this
challenge,
synthetic
scaffolds
are
widely
developed,
but
remarkably
few
translated
to
the
clinic
due
poor
performance
vivo.
Here,
it
is
demonstrated
how
architectural
design
3D
printed
can
improve
vivo
outcomes.
Ceramic
with
different
pore
sizes
and
permeabilities,
similar
porosity
interconnectivity,
implanted
rabbit
calvaria
for
12
weeks,
then
explants
harvested
microcomputed
tomography
evaluation
volume
functionality
newly
formed
bone.
results
indicate
that
scaffold
pores
should
be
larger
than
390
µm
an
upper
limit
590
enhance
formation.
It
also
bimodal
topology-alternating
large
small
pores-enhances
new
substantially.
Moreover,
formation
stiffness
highly
influenced
by
scaffold's
permeability
direction
concerned.
This
study
demonstrates
manipulating
size
architecture
provides
useful
strategy
enhancing
Biomaterials Science,
Journal Year:
2019,
Volume and Issue:
8(1), P. 18 - 38
Published: Oct. 14, 2019
Meta-biomaterials
are
designer
biomaterials
with
unusual
and
even
unprecedented
properties
that
primarily
originate
from
their
geometrical
designs
at
different
(usually
smaller)
length
scales.
Advanced Healthcare Materials,
Journal Year:
2018,
Volume and Issue:
7(17)
Published: July 25, 2018
Abstract
Due
to
the
difficulty
in
fabricating
bioceramic
scaffolds
with
smaller
pore
sizes
by
current
3D
printing
technique,
effect
of
(below
400
µm)
printed
on
bone
regeneration
and
biomechanical
behavior
is
never
studied.
Herein
beta‐tricalcium
phosphate
(β‐TCP)
interconnected
pores
three
different
(100,
250,
are
fabricated
plotting.
The
resultant
then
implanted
into
rat
critical‐sized
calvarial
defects
without
any
seeded
cells.
A
custom‐designed
device
developed
investigate
properties
after
surgical
implantation
for
4,
8,
12
weeks.
100
µm
size
found
present
highest
maximum
load
stiffness,
comparable
those
autogenous
bone,
being
Micro‐computed
tomography
(micro‐CT)
histological
analysis
further
indicate
that
achieve
percentage
new
ingrowth,
which
correlates
their
best
vivo
properties.
This
study
demonstrates
tailoring
β‐TCP
a
range
3D‐plotting
can
be
facile
efficient
approach
enhanced
behaviors
repair.
