International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(8), P. 4088 - 4088
Published: April 7, 2022
The
presence
of
food
contaminants
can
cause
foodborne
illnesses,
posing
a
severe
threat
to
human
health.
Therefore,
rapid,
sensitive,
and
convenient
method
for
monitoring
is
eagerly
needed.
complex
matrix
interferences
samples
poor
performance
existing
sensing
probes
bring
significant
challenges
improving
detection
performances.
Nanocomposites
with
multifunctional
features
provide
solution
these
problems.
combination
the
superior
characteristics
magnetic
nanoparticles
(MNPs)
quantum
dots
(QDs)
fabricate
fluorescent
(MNPs@QDs)
nanocomposites
are
regarded
as
an
ideal
probe
analysis.
high-efficiency
pretreatment
rapid
fluorescence
concurrently
integrated
into
one
platform
using
MNPs@QDs
nanocomposites.
In
this
review,
contemporary
synthetic
strategies
MNPs@QDs,
including
hetero-crystalline
growth,
template
embedding,
layer-by-layer
assembly,
microemulsion
technique,
one-pot
method,
described
in
detail,
their
advantages
limitations
discussed.
recent
advances
detecting
metal
ions,
pathogens,
toxins,
pesticides,
antibiotics,
illegal
additives
comprehensively
introduced
from
perspectives
modes
review
ends
current
opportunities
practical
applications
prospects
analysis,
aiming
promote
enthusiasm
research.
Chemical Society Reviews,
Journal Year:
2021,
Volume and Issue:
50(15), P. 8669 - 8742
Published: Jan. 1, 2021
Inorganic
nanomaterials
that
have
inherently
exceptional
physicochemical
properties
(e.g.,
catalytic,
optical,
thermal,
electrical,
or
magnetic
performance)
can
provide
desirable
functionality
drug
delivery,
diagnostics,
imaging,
therapy)
considerable
potential
for
application
in
the
field
of
biomedicine.
However,
toxicity
be
caused
by
long-term,
non-specific
accumulation
these
inorganic
healthy
tissues,
preventing
their
large-scale
clinical
utilization.
Over
past
several
decades,
emergence
biodegradable
and
clearable
has
offered
to
prevent
such
long-term
toxicity.
In
addition,
a
comprehensive
understanding
design
metabolic
pathways
within
body
is
essential
enabling
expansion
theranostic
applications
various
diseases
advancing
trials.
Thus,
it
critical
importance
develop
biomedical
applications.
This
review
systematically
summarizes
recent
progress
nanomaterials,
particularly
cancer
theranostics
other
disease
therapies.
The
future
prospects
opportunities
this
rapidly
growing
are
also
discussed.
We
believe
timely
will
stimulate
guide
additional
in-depth
studies
area
nanomedicine,
as
rapid
vivo
clearance
degradation
likely
prerequisite
translation
with
unique
functionality.
Advanced Science,
Journal Year:
2021,
Volume and Issue:
8(10)
Published: March 12, 2021
As
a
novel
noninvasive
therapeutic
modality
combining
low-intensity
ultrasound
and
sonosensitizers,
sonodynamic
therapy
(SDT)
is
promising
for
clinical
translation
due
to
its
high
tissue-penetrating
capability
treat
deeper
lesions
intractable
by
photodynamic
(PDT),
which
suffers
from
the
major
limitation
of
low
tissue
penetration
depth
light.
The
effectiveness
feasibility
SDT
are
regarded
rely
on
not
only
development
stable
flexible
apparatus,
but
also
screening
sonosensitizers
with
good
specificity
safety.
To
give
an
outlook
equipment,
key
technologies
discussed
according
five
aspects
including
ultrasonic
dose
settings,
sonosensitizer
screening,
tumor
positioning,
temperature
monitoring,
reactive
oxygen
species
(ROS)
detection.
In
addition,
some
state-of-the-art
multifunctional
equipment
integrating
diagnosis
treatment
accurate
introduced.
Further,
overview
provided
small
molecular
sensitizers
nano/microenhanced
sensitizers.
Several
types
nanomaterial-augmented
in
discussion,
porphyrin-based
nanomaterials,
porphyrin-like
inorganic
organic-inorganic
hybrid
nanomaterials
different
strategies
improve
efficacy.
There
no
doubt
that
rapid
will
be
promoted
advanced
smart
nanomaterial-based
sonosensitizer,
multidisciplinary
collaboration.
Bioactive Materials,
Journal Year:
2021,
Volume and Issue:
6(11), P. 4209 - 4242
Published: April 27, 2021
Molybdenum
is
a
trace
dietary
element
necessary
for
the
survival
of
humans.
Some
molybdenum-bearing
enzymes
are
involved
in
key
metabolic
activities
human
body
(such
as
xanthine
oxidase,
aldehyde
oxidase
and
sulfite
oxidase).
Many
molybdenum-based
compounds
have
been
widely
used
biomedical
research.
Especially,
MoS2-nanomaterials
attracted
more
attention
cancer
diagnosis
treatment
recently
because
their
unique
physical
chemical
properties.
MoS2
can
adsorb
various
biomolecules
drug
molecules
via
covalent
or
non-covalent
interactions
it
easy
to
modify
possess
high
specific
surface
area,
improving
its
tumor
targeting
colloidal
stability,
well
accuracy
sensitivity
detecting
biomarkers.
At
same
time,
near-infrared
(NIR)
window,
has
excellent
optical
absorption
prominent
photothermal
conversion
efficiency,
which
achieve
NIR-based
phototherapy
NIR-responsive
controlled
drug-release.
Significantly,
modified
MoS2-nanocomposite
specifically
respond
microenvironment,
leading
accumulation
site
increased,
reducing
side
effects
on
non-cancerous
tissues,
improved
therapeutic
effect.
In
this
review,
we
introduced
latest
developments
MoS2-nanocomposites
therapy,
mainly
focusing
biosensors,
bioimaging,
chemotherapy,
phototherapy,
microwave
hyperthermia,
combination
therapy.
Furthermore,
also
discuss
current
challenges
prospects
treatment.
Advanced Functional Materials,
Journal Year:
2022,
Volume and Issue:
32(34)
Published: June 24, 2022
Abstract
MXenes
(viz.,
transition
metal
carbides,
carbonitrides,
and
nitrides)
have
emerged
as
a
new
subclass
of
2D
materials.
Due
to
their
outstanding
physicochemical
biological
properties,
gained
much
attention
in
the
biomedical
field
recent
years,
including
drug
delivery
systems,
regenerative
medicine,
biosensing.
Additionally,
incorporation
into
hydrogels
has
garnered
significant
interest
engineering
an
electroactive
mechanical
nanoreinforcer
capable
converting
nonconductive
scaffolds
excellent
conductors
electricity
with
impressive
effect
on
properties
for
organs
tissues
such
cardiac,
skeletal
muscle,
nerve.
However,
many
questions
problems
remain
unresolved
that
need
be
answered
usher
these
materials
toward
true
destiny.
Thus,
this
review
paper
aims
provide
overview
design
applications
MXene‐integrated
composites
applications,
cardiac
tissue
engineering,
wound
healing,
infection
therapy,
cancer
biosensors.
Moreover,
current
challenges
limitations
utilizing
vivo
are
highlighted
discussed,
followed
by
its
prospects
guideline
possible
various
futuristic
applications.
This
article
will
inspire
researchers,
who
search
opportunities,
using
nanomaterial
Frontiers in Chemistry,
Journal Year:
2021,
Volume and Issue:
9
Published: July 29, 2021
Photothermal
therapy
is
a
very
promising
treatment
method
in
the
field
of
cancer
therapy.
The
photothermal
nanomaterials
near-infrared
region
(NIR-I,
750-900
nm)
attracts
extensive
attention
recent
years
because
good
biological
penetration
NIR
light.
However,
depth
still
not
enough
for
solid
tumors
due
to
high
tissue
scattering.
light
second
(NIR-II,
1000-1700
allows
deeper
penetration,
higher
upper
limit
radiation
and
greater
tolerance
than
that
NIR-I,
it
shows
application
potential
conversion.
This
review
summarizes
properties
Au
nanomaterials,
two-dimensional
materials,
metal
oxide
sulfides
polymers
NIR-II
their
prospects
It
will
arouse
interest
scientists
as
well
nanomedicine.
Journal of Materials Chemistry A,
Journal Year:
2021,
Volume and Issue:
9(33), P. 17569 - 17591
Published: Jan. 1, 2021
The
photothermal
applications
of
2D
nanomaterials
in
therapy,
water
evaporation,
thermochemical
reactions,
light-driven
actuators,
electrodes,
energy
storage,
wearable
heaters
and
bacterial
inhibition.
Advanced Science,
Journal Year:
2021,
Volume and Issue:
8(5)
Published: Jan. 15, 2021
Abstract
Cancer
has
been
one
of
the
major
threats
to
lives
human
beings
for
centuries.
Traditional
therapy
is
more
or
less
faced
with
certain
defects,
such
as
poor
targeting,
easy
degradation,
high
side
effects,
etc.
Therefore,
in
order
improve
treatment
efficiency
drugs,
an
intelligent
drug
delivery
system
(DDS)
considered
a
promising
solution
strategy.
Due
their
special
structure
and
large
specific
surface
area,
2D
materials
are
be
good
platform
delivery.
Black
phosphorus
(BP),
new
star
family,
recommended
have
potential
construct
DDS
by
virtue
its
outstanding
photothermal
(PTT),
photodynamic
(PDT),
biodegradable
properties.
This
tutorial
review
intended
provide
introduction
current
advances
BP‐based
DDSs
cancer
therapy,
which
covers
topics
from
construction,
classified
types
platforms,
stimuli‐responsive
controlled
release.
Moreover,
applications
including
mono‐,
bi‐,
multi‐modal
synergistic
well
research
biocompatibility
also
discussed.
Finally,
status
future
prospects
summarized.