Recent advances in cascade radical cyclization of radical acceptors for the synthesis of carbo- and heterocycles

Organic Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 8(6), P. 1345 - 1363

Published: Jan. 1, 2021

This review is devoted to highlighting main achievements in the development of cascade radical cyclization acceptors for synthesis carbo- and heterocycles.

Language: Английский

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Visible-light-initiated tandem synthesis of difluoromethylated oxindoles in 2-MeTHF under additive-, metal catalyst-, external photosensitizer-free and mild conditions

Chinese Chemical Letters, Journal Year: 2021, Volume and Issue: 32(6), P. 1907 - 1910

Published: Jan. 18, 2021

Language: Английский

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Synergistic cooperative effect of CF₃SO₂Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation

Green Chemistry, Journal Year: 2020, Volume and Issue: 23(1), P. 496 - 500

Published: Nov. 26, 2020

A practical method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated CF₃SO₂Na/2-butoxyethyl ether synergistic catalyzed oxygenation sulfides was developed.

Language: Английский

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Visible-light-induced cascade reaction: a sustainable approach towards molecular complexity

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 21(8), P. 1591 - 1628

Published: Jan. 1, 2023

Photoredox catalysis has demonstrated rapid evolution in the field of synthetic organic chemistry. On other hand, splendour cascade reactions providing complex molecular architectures renders them a cutting-edge research area. Therefore, merging photocatalysis with synthesis brings out paradigm immense potential. The development photocascade for target molecule particular skeleton and stereochemical framework presents certain challenges but provides robust environmentally benign alternative. This comprehensive review assembles all accomplishments highlights visible-light-induced literature coverage up to October 2022.

Language: Английский

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Visible-light-promoted radical cyclisation of unactivated alkenes in benzimidazoles: synthesis of difluoromethyl- and aryldifluoromethyl-substituted polycyclic imidazoles

Beilstein Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: 21, P. 234 - 241

Published: Jan. 30, 2025

An efficient and eco-friendly approach for synthesizing difluoromethyl- aryldifluoromethyl-substituted polycyclic imidazoles was established via a visible-light-promoted radical cyclization reaction. This method employed the readily accessible inexpensive CF 2 HCO H or PhCF COOH, along with benzimidazoles bearing unactivated alkenes PhI(OAc) as substrates, proceeded without need of any base, metal catalyst, photocatalyst additive. In total, 24 examples were examined, all them successfully underwent reaction to produce target products in good excellent yields. Mechanistic studies revealed that proceeds pathway.

Language: Английский

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Visible‐Light‐Driven Cyclizations

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(4), P. 635 - 697

Published: Jan. 13, 2024

Abstract In recent years, the interest to develop cyclizations promoted by visible light has been gaining a lot of attention due its sustainability aspect. this review, we summarize most important advances in period describing methods used generate different ring sizes, while focusing on mechanistic details these reactions.

Language: Английский

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Current developments in the synthesis of 4-chromanone-derived compounds

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(37), P. 7995 - 8008

Published: Jan. 1, 2021

The chroman-4-one framework is a significant structural entity that belongs to the class of oxygen-containing heterocycles. It acts as major building block in large medicinal compounds, and synthetic compounds exhibit broad variety remarkable biological pharmaceutical activities. Several studies have been performed improve methodologies 4-chromanone-derived compounds. This review focuses on methods preparation reported derivatives from 2016 2021.

Language: Английский

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Visible-light-induced chemoselective reactions of quinoxalin-2(1H)-ones with alkylboronic acids under air/N2 atmosphere

Chinese Chemical Letters, Journal Year: 2021, Volume and Issue: 32(12), P. 4033 - 4037

Published: June 11, 2021

Language: Английский

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Switchable aroylation and diaroylation of allyl sulfones with aldehydes enabled by decatungstate photocatalysis

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(14), P. 5614 - 5619

Published: Jan. 1, 2022

A tetrabutylammonium decatungstate (TBADT) mediated photocatalytic controllable aroylation or diaroylation of allyl sulfones was established to synthesize β,γ-unsaturated ketones and 1,5-diketones in moderate excellent yields, respectively.

Language: Английский

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Visible light-promoted photocatalyst-free activation of persulfates: a promising strategy for C–H functionalization reactions

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(16), P. 3249 - 3262

Published: Jan. 1, 2022

This review summarizes visible light-induced photocatalyst-free C–H functionalization reactions employing persulfates. The proceeded through the generation of persulfate radical anions from persulfates under light irradiation.

Language: Английский

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