Asian Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
10(11), P. 2820 - 2847
Published: Aug. 30, 2021
Abstract
Electro‐organic
reactions
are
now
considered
as
one
of
the
most
efficient
and
environmentally
benign
methodologies
to
synthesize
highly
functionalized
motifs
like
difunctionalized
unsaturated
compounds
from
readily
available
substrates.
Excellent
regioselectivity,
functional
group
tolerance
broad
range
substrates
main
advantages
electrochemical
difunctionalization
reactions.
Alkenes
alkynes
accept
radical
or
ionic
derivatives
which
makes
it
vital
precursors
for
synthesis
industrially
relevant
biologically
active
molecules
through
difunctionalization.
This
review
aims
provide
readers
an
excellent
coverage
different
alkenes
such
1,2‐homodifunctionalization,
1,2‐heterodifunctionalization,
rearrangement,
ipso
‐migration,
cyclization
dehydrogenative
annulation
The Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
86(1), P. 917 - 928
Published: Dec. 7, 2020
We
developed
a
green
method
for
the
synthesis
of
spiro[4.5]trienones
through
an
electrochemical
oxidative
halocyclization
with
N-aryl
alkynamides.
This
reaction
was
conducted
under
metal-catalyst-
and
exogenous-oxidant-free
conditions
at
room
temperature.
Using
readily
available
LiCl,
LiBr,
LiI
as
halogen
source,
variety
dearomative
halo-spirocyclization
products
were
obtained
in
good
to
excellent
yields
broad
scope
functional
group
tolerance.
Angewandte Chemie International Edition,
Journal Year:
2020,
Volume and Issue:
60(9), P. 4619 - 4624
Published: Dec. 3, 2020
Abstract
The
electrochemical
three‐component
assembly
of
isoquinolines
has
been
accomplished
by
ruthenaelectro‐catalyzed
C−H/N−H
functionalization.
robustness
the
electrocatalysis
was
reflected
an
ample
substrate
scope,
efficient
electrooxidation,
and
operationally
friendly
procedure.
isolation
key
intermediates
detailed
mechanistic
studies,
including
unprecedented
cyclovoltammetric
analysis
a
seven‐membered
ruthenacycle,
provided
support
for
unusual
ruthenium(II/III/I)
regime.
Organic & Biomolecular Chemistry,
Journal Year:
2021,
Volume and Issue:
19(12), P. 2578 - 2602
Published: Jan. 1, 2021
In
this
review
we
target
sp,
sp2and
sp3carbon
fluorination,
chlorination,
bromination
and
iodination
reactions
using
electrolysis
as
a
redox
medium.
Mechanistic
insights
substrate
reactivity
are
also
discussed.
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
9(10), P. 2786 - 2791
Published: Jan. 1, 2022
We
introduced
an
electrochemical
oxidative
radical
cascade
cyclization
of
olefinic
amides
and
diselenides
without
a
transition-metal
catalyst
external
oxidant.
This
selenocyclization
reaction
provided
facile
method
to
construct
C–Se
C–O
bonds
in
one
step.
Green Chemistry,
Journal Year:
2022,
Volume and Issue:
24(9), P. 3697 - 3703
Published: Jan. 1, 2022
Natural
allocolchicine
and
analogues
derived
thereof
a
tricyclic
6–7–6-system
have
been
found
as
key
scaffold
of
various
biologically
relevant
molecules.
Green Chemistry,
Journal Year:
2020,
Volume and Issue:
23(2), P. 763 - 766
Published: Dec. 11, 2020
A
highly
stereoselective
synthesis
of
thiocyanated
enaminones
was
achieved
by
an
electrochemical
process,
which
involved
C–H
bond
thiocyanation
and
vinyl
C–N
transamination.
