Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(20), P. 7983 - 7987
Published: Jan. 1, 2023
An
atom-
and
step-economical,
efficient
eco-friendly
method
for
constructing
naphthoselenazol-2-amines
through
a
visible-light
photocatalytic
multi-component
reaction
under
aqueous
phase
conditions
is
reported.
Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(14), P. 5539 - 5542
Published: Jan. 1, 2023
With
formaldehyde
as
an
atom-economical
carbonyl
synthon,
the
EtOH-catalyzed
electrochemical
multicomponent
synthesis
of
various
imidazolidine-fused
sulfamidates
under
organic
oxidant-free,
energy-saving
and
mild
conditions
was
developed.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(7), P. 6581 - 6581
Published: April 1, 2023
Multicomponent
reactions
(MCRs)
have
emerged
as
a
powerful
strategy
in
synthetic
organic
chemistry
due
to
their
widespread
applications
drug
discovery
and
development.
MCRs
are
flexible
transformations
which
three
or
more
substrates
react
form
structurally
complex
products
with
high
atomic
efficiency.
They
being
increasingly
appreciated
highly
exploratory
evolutionary
tool
by
the
medicinal
community,
opening
door
sustainable,
cost-effective
rapid
synthesis
of
biologically
active
molecules.
In
recent
years,
MCR-based
strategies
found
extensive
application
field
discovery,
several
anticancer
drugs
been
synthesized
through
MCRs.
this
review,
we
present
an
overview
representative
literature
examples
documenting
different
approaches
development
new
drugs.
Tetrahedron Chem,
Journal Year:
2024,
Volume and Issue:
9, P. 100070 - 100070
Published: Feb. 28, 2024
Bicyclo[1.1.0]butanes
(BCBs)
and
[1.1.1]propellanes
(tricyclo[1.1.1.01,3]pentanes,
TCPs)
are
structurally
unique
compounds
with
different
chemical
properties.
Strain-release
driven
reactions
have
emerged
as
an
atom-
step-economic
strategy
for
the
organic
synthesis.
Using
this
strategy,
a
variety
of
functional
ring
molecules
been
efficiently
synthesized,
including
various
cyclobutane
molecules,
bicyclo[2.1.1]hexanes,
bicyclo[1.1.1]pentanes,
others.
More
specifically,
these
strain
release-driven
include
aspects
nucleophilic
addition,
radical
electrophilic
or
transition
metal
catalysis.
This
review
will
discuss
recent
developments
in
strain-release
transformations
bicyclo[1.1.0]butanes
[1.1.1]propellanes.
This
review
highlights
the
recent
advances
in
multi-component
reactions
for
synthesizing
heterocyclic
compounds
via
green
approaches
including
photoredox
catalysis,
electrochemical
activation,
catalyst-free
methods
and
use
of
water
as
sole
solvent.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Nov. 23, 2023
Abstract
Captopril
(CAP)
is
a
safe,
cost-effective,
and
environmentally
organic
compound
that
can
be
used
as
an
effective
organo-catalyst.
Functional
groups
of
captopril
make
it
capable
to
attach
solid
support
acting
promoters
in
transformations.
In
this
work,
was
attached
the
surface
magnetic
graphene
nitride
by
employing
linker
agent.
The
synthesized
composite
efficiently
catalyzed
two
multicomponent
reactions
including
synthesis
1,2,3,6-tetrahydropyrimidine
2-amino-4
H
-chromene
derivatives.
A
large
library
functional
targeted
products
mild
reaction
conditions.
More
importantly,
catalyst
stable
magnetically
recycled
reused
for
at
least
five
runs
without
losing
catalytic
activity.
Russian Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
92(12), P. RCR5104 - RCR5104
Published: Dec. 1, 2023
After
the
appearance
of
green
chemistry
concept,
which
was
introduced
in
vocabulary
early
1990s,
its
main
statements
have
been
continuously
developed
and
modified.
Currently,
there
are
10–12
cornerstones
that
should
form
basis
for
an
ideal
chemical
process.
This
review
analyzes
accumulated
experience
achievements
towards
design
products
processes
reduce
or
eliminate
use
generation
hazardous
substances.
The
presents
views
leading
Russian
scientists
specializing
various
fields
this
subject,
including
homogeneous
heterogeneous
catalysis,
fine
basic
organic
synthesis,
electrochemistry,
polymer
chemistry,
based
on
bio-renewable
feedstocks
energetic
compounds
materials.
A
new
approach
to
quantitative
evaluation
environmental
friendliness
by
authors
is
described.
<br>
bibliography
includes
1761.
Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
12(8)
Published: July 20, 2023
Abstract
In
terms
of
pharmaceuticals
and
biological
applications,
synthesis
complex
organic
molecules
is
a
significant
fast‐developing
area.
this
context,
electrosynthesis
an
alternative
way
to
the
traditional
methods
for
chemo‐,
regio‐,
stereoselective
syntheses.
Electro‐organic
reactions
occur
at
room
temperature
normal
pressure,
through
transferring
electrons.
It
has
been
found
that
mild
approach
preparing
electrophilic
substrates,
bases,
nucleophiles
in
situ
,
from
highly
stable
low‐level
reagents;
which
can
be
further
applied
make
heterocycles
more
accessible.
While
several
promising
exist,
multi‐component
(MCRs)
have
drawn
much
attention
both
academia
industry
worldwide,
since
they
are
cost‐efficient
environmentally
friendly.
Combining
MCRs
produced
great
strategy
field
research.
This
review
focuses
on
recent
advances
electrochemical
heterocyclic
compounds
via
reactions,
reported
between
2015
March
2023.
