Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(21), P. 4202 - 4211
Published: Jan. 1, 2024
Pillararenes
have
gained
great
interest
among
researchers
in
many
fields
due
to
their
symmetric
structure
and
facile
functionalization.
In
this
review,
we
summarize
recent
progress
for
pillararenes
as
antimicrobial
agents,
ranging
from
cationic
peptide-modified
sugar-functionalized
pillararenes.
Moreover,
structure-activity
relationships
are
presented,
mechanisms
of
action
discussed.
As
a
state-of-the-art
technology,
opportunities
outlook
also
outlined
emerging
field.
Overall,
potent
inhibitory
activity
high
biocompatibility
give
them
potential
the
development
novel
agents.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(16)
Published: Jan. 11, 2024
Cancer
poses
a
significant
challenge
to
global
public
health,
seriously
threatening
human
health
and
life.
Although
various
therapeutic
strategies,
such
as
chemotherapy
(CT),
radiotherapy,
phototherapy,
starvation
therapy,
are
applied
cancer
treatment,
their
limited
effect,
severe
side
effects,
unsatisfactory
drug
release
behavior
need
be
carefully
considered.
Thus,
there
is
an
urgent
develop
efficient
delivery
strategies
for
improving
treatment
efficacy
realizing
on-demand
delivery.
Notably,
pillararenes,
emerging
class
of
supramolecular
macrocycles,
possess
unique
properties
highly
tunable
structures,
superior
host-guest
chemistry,
facile
modification,
good
biocompatibility,
which
widely
used
in
therapy
achieve
controllable
reduce
the
toxic
effects
on
normal
tissues
under
internal/external
stimuli
conditions.
This
review
summarizes
recent
advance
stimuli-responsive
systems
(SDSs)
based
pillararenes
tumor
from
perspectives
different
assembly
methods
hybrid
materials,
including
molecular-scale
SDSs,
nano
self-assembly
systems,
nanohybrid
SDSs.
Moreover,
prospects
critical
challenges
SDSs
also
discussed.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(65), P. 8526 - 8536
Published: Jan. 1, 2024
This
feature
article
comprehensively
summarizes
the
application
of
A–D–A
photosensitizers
in
field
phototheranostics
from
perspectives
both
molecular
design
and
nanodrug
construction.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
This
feature
article
comprehensively
summarizes
the
research
progress
related
to
strategy
of
singlet
oxygen
storage
and
its
controlled
release
in
photodynamic
therapy
dark
or
hypoxic
tumors.
