Electrochemical Oxidative 1,2-Dithiocyanation: Access to Functionalized Alkenes and Alkynes DOI

Ning Zhang,

Zhen Cheng,

Yu Xia

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(11), P. 8064 - 8075

Published: May 17, 2024

Reported herein is the 1,2-dithiocyanation of alkenes and alkynes

Language: Английский

Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles DOI
Qiong Yan, Xu Wu, Hao Jiang

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 502, P. 215622 - 215622

Published: Dec. 26, 2023

Language: Английский

Citations

77

Electrochemical chemoselective thiocarbamylation of late-stage Tyr-containing drugs and peptides DOI

Wan‐Jie Wei,

Xinyu Wang, Haitao Tang

et al.

Science China Chemistry, Journal Year: 2024, Volume and Issue: 67(10), P. 3382 - 3388

Published: Aug. 2, 2024

Language: Английский

Citations

26

Recent progress in the electrochemical selenofunctionalization of alkenes and alkynes DOI
Pei Qu,

You‐Qin Jiang,

Yong‐Hao Wang

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(19), P. 7485 - 7507

Published: Jan. 1, 2023

The recent advances on the electrochemical selenofunctionalization of unsaturated C–C bonds were comprehensively summarized in this review.

Language: Английский

Citations

32

Electrochemical difunctionalization of alkenes and alkynes for the synthesis of organochalcogens involving C–S/Se bond formation DOI
Jianchao Liu, Jie‐Ping Wan, Yunyun Liu

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 11(2), P. 597 - 630

Published: Nov. 23, 2023

This review highlights the recent progress in electrochemical difunctionalization of alkenes and alkynes involving C–S/Se bond formation to access organochalcogen frameworks.

Language: Английский

Citations

30

Electrochemical oxidative cross coupling of NH-sulfoximines with disulfides DOI
Shuai Zhang, Meiqian Hu, Changsheng Qin

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(6), P. 2576 - 2583

Published: Jan. 1, 2024

An electrochemical method for thioetherification of NH-sulfoximines with disulfides is reported. The utilization electrochemistry facilitating these reactions eliminates the necessity external oxidants, bases, and metal catalysts.

Language: Английский

Citations

11

Tailoring Highly Branched Poly(β-amino ester)s for Efficient and Organ-Selective mRNA Delivery DOI
Haiyang Yong, Lixin Lin, Zhili Li

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: 24(30), P. 9368 - 9376

Published: July 16, 2024

Development of mRNA therapeutics necessitates targeted delivery technology, while the clinically advanced lipid nanoparticles face difficulty for extrahepatic delivery. Herein, we design highly branched poly(β-amino ester)s (HPAEs) efficacious organ-selective through tailoring their chemical compositions and topological structures. Using an "A2+B3+C2" Michael addition platform, a combinatorial library 219 HPAEs with varied backbone structures, terminal groups, branching degrees are synthesized. The structures provide enhanced serum resistance significantly higher expression in vivo. amine determine organ-selectivity following systemic administration: morpholine facilitates liver targeting, ethylenediamine favors spleen delivery, methylpentane enables to liver, spleen, lungs simultaneously. This study represents comprehensive exploration structure–activity relationship governing both efficiency by HPAEs, suggesting promising candidates treating various organ-related diseases.

Language: Английский

Citations

10

Electrochemically Enabled Synthesis of Multi-substituted Pyrazoles via a Radical Cyclization Cascade DOI

Wan‐Jie Wei,

Y. M. Zeng,

Xianfeng Liang

et al.

Green Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We have developed a mild and efficient electrochemical reduction approach employing aryl diazonium salts as dual synthons to synthesize valuable multi-substituted pyrazoles for the first time.

Language: Английский

Citations

1

Electrocatalytic Multicomponent Cascade Cross‐Coupling for the Synthesis of Chalcogenosulfonates DOI
Zhiheng Zhao, Hongyan Yan, Yaqin Zhou

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(17), P. 2049 - 2055

Published: May 7, 2024

Comprehensive Summary An electrocatalytic multicomponent cascade cross‐coupling for the synthesis of chalcogenosulfonates has been established. This approach does not require use transition metals, acids, and external oxidants. The gentle conditions tolerance to a wide variety functional groups permit derivatization complex indoles.

Language: Английский

Citations

5

Advances in photochemical/electrochemical synthesis of heterocyclic compounds from carbon dioxide DOI
Yuyang Xie, Ying‐Ming Pan

Green Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This paper reviews progress in the photochemical/electrochemical construction of heterocyclic compounds using CO 2 , differentiating between various reaction types and elucidating their underlying mechanisms as well potential applications.

Language: Английский

Citations

5

Electrochemical Oxidative Carbonylation of NH-Sulfoximines DOI
Mingzhe Li,

Mengyu Peng,

Wenxiu Huang

et al.

Organic Letters, Journal Year: 2023, Volume and Issue: 25(41), P. 7529 - 7534

Published: Oct. 11, 2023

The electrochemical synthesis of N-aroylsulfoximines features the use tetra-n-butylammonium iodide (TBAI) as medium and a broad substrate scope, thus affording wide range N-aroylated sulfoximines in moderate to good yields. advantages this strategy are augmented by mild reaction conditions that external oxidant-free, ligand-free, easy scale up gram scale. Both control experiments mechanistic studies revealed whole process proceeded through palladium (II/IV/II) catalytic cycle.

Language: Английский

Citations

12