ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(19), P. 23062 - 23075
Published: Oct. 1, 2024
Language: Английский
ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(19), P. 23062 - 23075
Published: Oct. 1, 2024
Language: Английский
Gels, Journal Year: 2024, Volume and Issue: 10(2), P. 147 - 147
Published: Feb. 14, 2024
Wound healing is a physiological process occurring after the onset of skin lesion aiming to reconstruct dermal barrier between external environment and body. Depending on nature duration process, wounds are classified as acute (e.g., trauma, surgical wounds) chronic diabetic ulcers) wounds. The latter take several months heal or do not (non-healing wounds), usually prone microbial infection represent an important source morbidity since they affect millions people worldwide. Typical wound treatments comprise debridement, grafts/flaps) non-surgical topical formulations, dressings) methods. Modern experimental approaches include among others three dimensional (3D)-(bio)printed dressings. present paper reviews recently developed 3D (bio)printed hydrogels for applications, especially focusing results their in vitro vivo assessment. advanced hydrogel constructs were printed using different types bioinks natural and/or synthetic polymers mixtures with biological materials) printing methods extrusion, digital light processing, coaxial microfluidic bioprinting, etc.) incorporated various bioactive agents growth factors, antibiotics, antibacterial agents, nanoparticles, cells fibroblasts, keratinocytes, mesenchymal stem cells, endothelial etc.).
Language: Английский
Citations
20Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160379 - 160379
Published: Feb. 1, 2025
Language: Английский
Citations
3Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(14)
Published: Feb. 2, 2024
Abstract The limitations of protein‐based hydrogels, including their insufficient mechanical properties and restricted biological functions, arise from the highly specific functions proteins as natural building blocks. A potential solution to overcome these shortcomings is development protein–protein which integrate structural functional proteins. In this study, a hydrogel formed by crosslinking bovine serum albumin (BSA) genetically engineered intrinsically disordered collagen‐like protein (CLP) through Ag─S bonding introduced. approach involves thiolating lysine residues BSA CLP with Ag + ions, utilizing thiolation free‐cysteines CLP. resulting hydrogels exhibit exceptional properties, notable plasticity, inherent self‐healing capabilities, gel–sol transition in response redox conditions. comparison standalone demonstrate enhanced cellular viability, improved migration. vivo experiments provide conclusive evidence accelerated wound healing, observed not only murine models streptozotocin (Step)‐induced diabetes but also zebrafish subjected UV‐burn injuries. Detailed mechanistic insights, combined assessments proinflammatory cytokines expression epidermal differentiation‐related proteins, robustly validate hydrogel's effectiveness promoting repair.
Language: Английский
Citations
11Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(8), P. 2070 - 2082
Published: Jan. 1, 2024
An innovative wound microenvironment self-adaptive hydrogel, that encapsulates drug-loaded liposomes was developed to promote the healing of diabetic wounds.
Language: Английский
Citations
7Heliyon, Journal Year: 2024, Volume and Issue: 10(20), P. e38481 - e38481
Published: Sept. 26, 2024
Language: Английский
Citations
7Aggregate, Journal Year: 2025, Volume and Issue: unknown
Published: April 22, 2025
ABSTRACT Recent advancements in hydrogel‐based flexible materials have revolutionized wound healing and monitoring strategies. These offer promising solutions for medical treatment real‐time diagnostics. Their rich water content, biocompatibility, tunable properties closely mimic the natural extracellular matrix, supporting regeneration. Unlike traditional materials, systems address critical issues such as material stability toxicity while integrating advanced devices. This review highlights latest innovations materials. It focuses on flexibility, potential integration with smart systems. The covers design principles fabrication techniques nanofibers, elastomers, conducting polymers. also discusses development of electronic skin innovative dressings. In addition, explains how sensing capabilities, stimuli‐responsive functions, antibacterial agents are incorporated into these Finally, article examines challenges future directions field. emphasizes transformative multifunctional improving continuous monitoring.
Language: Английский
Citations
1Environmental Science Nano, Journal Year: 2024, Volume and Issue: 11(4), P. 1636 - 1653
Published: Jan. 1, 2024
Due to the excessive residues and serious adverse effects, it is urgent develop an efficient method detect Hg 2+ As 3+ in drinking water protect human health.
Language: Английский
Citations
5Materials Advances, Journal Year: 2024, Volume and Issue: 5(10), P. 4078 - 4090
Published: Jan. 1, 2024
The review discusses advancements in amyloid fibril-based materials and their applications healthcare, sensing, the environment. These biomaterials are sustainable greener alternatives to conventional synthetic materials.
Language: Английский
Citations
5Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: 705, P. 135553 - 135553
Published: Oct. 13, 2024
Language: Английский
Citations
3Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Abstract 3D printing of protein materials for creating bioactive scaffolds has attracted significant interest. However, achieving controllable and stable while replicating the ordered structure found in natural remains a key challenge. Herein, universally applicable temperature‐dependent aggregation (TPA) strategy is reported to manipulate unfolding, relaxation, reorganization chains enable amyloid‐like proteins. The disruption internal disulfide bonds induces unfolding relaxation protein, leading formation an amorphous sol through chain entanglement as primary cross‐linking points. These relaxed further aggregate conformational transition initiate rich β‐sheet structures at high temperature, resulting gel with nanocrystals serving secondary This facilitates precise extrusion‐based proteinaceous hierarchically structure. biomedical potential this 3D‐printed scaffold preliminarily validated its biomineralization capability following application bone tissue regeneration using rat skull defect models. demonstrates facile approach structural proteins vitro holds great field protein‐based scaffolds.
Language: Английский
Citations
3