Relationship of oxidative balance score to gallstone prevalence and gallbladder surgery in American adults: evidence from NHANES 2017-2020 DOI Creative Commons

Shouxin Wei,

Sijia Yu,

Zhengwen Xu

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 28, 2024

Abstract Gallstones represent a common gastrointestinal disorder, affecting approximately 10-20% of the global population. Oxidative stress plays pivotal role in pathogenesis gallstones; however, there remains lack effective clinical indicators to predict their formation. This study addresses this gap by investigating relationship between oxidative balance score (OBS) and incidence gallstones gallbladder surgery, utilizing data from National Health Nutrition Examination Survey (NHANES) 2017 2020. Methods: investigated association OBS occurrence surgery analyzing NHANES for period 2017–2020, adjusting potential confounders such as age, sex, race, comorbidities. Various statistical analyses were applied, including multivariate logistic regression, subgroup analyses, smoothed curve-fitting models.Results: The results revealed significant negative correlation risks both with each one-unit increase associated 2.6% reduction gallstone risk (OR=0.974, 95% CI: 0.958-0.990) 3.3% (OR=0.967, 0.950-0.983). Subgroup confirmed consistency these associations across various demographic health-related factors. Furthermore, dose-response was observed higher reduced surgery.Conclusions: demonstrates that is lower rates offering new insights into link levels formation well surgical intervention. findings underscore valuable tool identifying at-risk populations informing personalized prevention strategies disease.

Language: Английский

Is meeting 24-hour movement guidelines associated with a lower risk of frailty among adults? DOI Creative Commons

Yuxing Liu,

Shuai Gao,

Zhigang Dou

et al.

International Journal of Behavioral Nutrition and Physical Activity, Journal Year: 2025, Volume and Issue: 22(1)

Published: Feb. 21, 2025

Language: Английский

Citations

1
Joint association of cardiovascular health and frailty with all-cause and cause-specific mortality: a prospective study DOI
Ning Ning, Xiaoting Fan, Yuan Zhang

et al.

Age and Ageing, Journal Year: 2024, Volume and Issue: 53(7)

Published: July 1, 2024

Abstract Background Poor cardiovascular health (CVH) and physical frailty were reported to increase mortality risk, but their joint effects have not been fully elucidated. Objectives We aimed explore the separate of CVH on based two perspectives Life’s Essential 8 (LE8) Framingham Risk Score (FRS). Methods 21 062 participants in National Health Nutrition Examination Survey (NHANES) from 2007 2018 involved this study. was evaluated by LE8 FRS, categorized into low, moderate high groups. Cox proportional hazard models applied estimate associations index (FI) with all-cause, disease (CVD) cancer mortality. Results Over a median follow-up period 87 months (95% CI: 86.0–88.0), 2036 deaths occurred. The linear dose–response relationships between CVH, observed (nonlinear P > .05). combination low CVH/frailty negatively associated all-cause [hazard ratio (HR) 95%CI: LE8*FI, 5.30 (3.74, 7.52); FRS*FI, 4.34 (3.20, 5.88)], CVD [low 6.57 (3.54, 12.22); 7.29 (3.92, 13.55)] 1.99 (1.14, 3.25); 2.32 (1.30, 4.15)], CVH/fit group as reference. Further stratified analyses showed that combined burden greater among young females. Conclusions Low independently jointly correlated risk deaths, especially

Language: Английский

Citations

5
Comparative Study of Frailty Assessment Measures in Predicting All-Cause Mortality: Insights From NHANES DOI
Jiacheng Yang,

Yijiang Ouyang,

Wenya Zhang

et al.

Journal of the American Medical Directors Association, Journal Year: 2025, Volume and Issue: 26(3), P. 105464 - 105464

Published: Feb. 1, 2025

Language: Английский

Citations

0
Association between the oxidative balance score and testosterone deficiency: a cross-sectional study of the NHANES, 2011–2016 DOI Creative Commons
Jiayi Liu,

Chuanyu Ma,

Yifu Leng

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 7, 2025

There is increasing recognition of the role oxidative balance in testosterone deficiency (TD). This study investigates association between score (OBS) and TD prevalence among adult males United States. Data were obtained from a cross-sectional 3276 men 2011–2016 National Health Nutrition Examination Survey. OBS was assessed based on 16 nutrient 4 lifestyle components. Multivariate logistic regression subgroup analyses conducted to calculate odds ratios (OR) 95% confidence intervals (CI) for prevalence. After adjusting potential confounders, negative linear observed (OR = 0.98, CI 0.97–1.00). Participants highest tertile had lower compared those lowest 0.92, 0.69–1.21). Lifestyle components significantly associated with 0.85, 0.81–0.90). Furthermore, least absolute shrinkage selection operator identified key most strongly TD, physical activity exerting greatest influence. A predictive nomogram model incorporating these demonstrated discriminatory power an area under curve 0.744 (95% 72.4–76.4%). In conclusion, this demonstrates inverse prevalence, suggesting regulation US males.

Language: Английский

Citations

0
Association between the oxidative balance score and mortality in patients with metabolic syndrome DOI Creative Commons
Yuqing Li, Ping Li, Ran Chu

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 18, 2025

Anti-oxidant/Pro-oxidant oxidant imbalance leads to chronic inflammation and insulin resistance can lead the development of metabolic syndrome (MetS). The oxidative balance score (OBS) is a tool for assessing stress associated with MetS risk. However, association between OBS mortality in patients remains unclear. This study analyzed 10,647 from 1999–2018 National Health Nutrition Examination Survey (NHANES). were calculated using combination 16 dietary 4 lifestyle factors. Multivariate Cox proportional hazards regression models, Kaplan–Meier survival analysis, restricted cubic splines (RCS), subgroup analyses used evaluate potential risk all-cause cardiovascular mortality. Sensitivity confirmed robustness results. found that was inversely MetS, result consistent across most subgroups. Both curve RCS analysis supported these findings. verify Maintaining an antioxidant-based diet may help reduce MetS. These findings underscore significance incorporating antioxidant-rich patterns behavioral practices strategies aimed at preventing managing

Language: Английский

Citations

0
Dietary total antioxidant capacity and frailty in Turkish community-dwelling and nursing home: cross-sectional study DOI Creative Commons
Ömer Turan, Volkan Özkaya

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: April 4, 2025

Background This study examines the relationship between dietary total antioxidant capacity, frailty, and nutritional status in Turkish older adults living community nursing homes. Methods included 160 (50% female) ( n = 80) a home 80). Anthropometric measurements were taken, BMI was calculated. Demographic characteristics, (MNA-SF: Mini Nutritional Assessment Short Form), frailty (FRAIL Scale), activities of daily (Katz ADL), three-day food consumption records assessed. Dietary capacity determined based on record. Results The mean ages groups similar (72.5 ± 6.0 72.2 5.9 years). Nursing residents had significantly higher rates chronic disease (91.3%) regular medication use (90.0%) p < 0.05). Overweight more prevalent among dwellers (50.0%, 0.05), while obesity common (26.2%, > Frail (32.5%) pre-frail (40.0%) compared to elderly (21.2 38.8%, respectively). Dependence ratios Community-dwelling participants lower risk malnutrition. While their carbohydrate intake lower, intakes protein, fat, ω -3 fatty acids, fiber, vitamins (except vitamin E), minerals. Frailty showed strong negative correlation with Katz r −0.56, 0.001) MNA-SF scores −0.44, 0.001), weak positive correlations observed TRAP, TEAC, FRAP3 values. A residential setting TORAC −0.424, TRAP −0.190, TEAC −0.257, VCEAC −0.241, 0.002) Conclusion Residential may affect nutrient intake, overall health adults.

Language: Английский

Citations

0
Gender-specific effects of Oxidative Balance Score on frailty prevalence in US adults: NHANES 2003-2018 analysis DOI
Qin Li, Yue Wei, Duo Chen

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Abstract Background: Frailty has been a growing public health concern as the global population ages. The Oxidative Balance Score (OBS) serves commonly utilized tool for evaluating an individual’s antioxidant status. However, its relationship with frailty hasn't thoroughly explored by gender, nor have specific OBS components linked to fully identified.. Methods: 6,994participants from 2003 2018 NHANES were included. Weighted multiple logistic regression, subgroup analysis, and restricted cubic spline curves used assess association between OBS, frailty. LASSO penalized regression was conducted identify key factors associated Results: Compared tertile1group, adjusted ORs tertile3group regarding total dietary lifestyle 0.66(95%CI:0.51-0.84),0.75(95%CI:0.58-0.96), 0.41(95%CI:0.30-0.56), respectively. In women, risk showed 'L'-shaped pattern, whereas exhibited 'U'-shaped curve. Conversely, in men, linear observed of identified factors, which build nomogram AUC 79.2%, indicating strong predictive accuracy. Conclusions: Higher is lower risk, gender differences. Identifying at-risk populations high through diet regulation are potential ways prevent

Language: Английский

Citations

0
Cross-sectional comparison of the association between three different insulin resistance surrogates and frailty: NHANES 1999-2018 DOI Creative Commons

Tianjie Lai,

Fenglei Guan,

Yunxian Chen

et al.

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 23, 2024

Background The correlation between various insulin resistance surrogates and frailty remains under investigation in the scientific community. Methods Data from NHANES (1999-2018) were used. We utilized weighted binary logistic regression, trend tests, RCS analysis, subgroup analysis to comprehensively assess link METS-IR, HOMA-IR, TyG, risk. Results results revealed a significant positive association high levels of TyG with risk all models. Notably, model 4, highest quintile METS-IR showed strongest (OR: 2.960, 95% CI: 2.219-3.949), HOMA-IR 2.522, 1.927-3.301) following closely behind. Trend tests (P for < 0.05). linear relationship nonlinearity > In contrast, exhibited U-shaped nonlinear Conclusion research identified risk, whereas displayed U-shaped, pattern frailty. Among varying examined, linkage was most pronounced top quintile.

Language: Английский

Citations

2
Association of the oxidative balance score and chronic kidney disease: insights from the national health and nutrition examination survey 2009–2018 DOI Creative Commons
Xinyun Chen, Zheng Wu, Xingyu Hou

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 27, 2024

Introduction Oxidative stress plays a pivotal role in the pathogenesis of chronic kidney disease (CKD). The oxidative balance score (OBS) was devised to quantify overall state, integrating pro-oxidant and antioxidant influences from both dietary intake lifestyle practices. aim this study delve into relationship between OBS CKD within adult population United States. Methods Utilizing data National Health Nutrition Examination Survey (NHANES) spanning 2009–2018, we derived 16 four factors. We employed weighted multivariate regression probe link CKD. Additionally, undertook subgroup analyses applied Restricted Cubic Spline Regression (RCS) for further analyses. Results This encompassed 19,444 participants. Logistic analysis consistently demonstrated protective effect higher on In Model 3, each unit increase associated with 2% reduction risk (95% CI: 0.97–0.99, p < 0.001) 4% reduced estimated glomerular filtration rate (eGFR) 0.95–0.98, 0.001). highest quintile (Q4) also showed significant reductions (OR: 0.66, 95% 0.53–0.82, eGFR 0.51, 0.37–0.69, 3. RCS revealed linear Subgroup indicated associations most subgroups, except those without hypertension or cardiovascular disease. interaction that age, hypertension, diabetes significantly modify association risk. Conclusion An elevated OBS, reflecting predominance antioxidants, correlates diminished American demographic. These insights emphasize potential influence equilibrium development

Language: Английский

Citations

2
The effect of dietary oxidation balance scores and volatile organic compounds exposures on inflammation DOI Creative Commons
Weipeng Zhang, Anqi Lin, Weiqiang Chen

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 286, P. 117163 - 117163

Published: Oct. 12, 2024

Language: Английский

Citations

0