Type 2 diabetes

The Lancet, Journal Year: 2022, Volume and Issue: 400(10365), P. 1803 - 1820

Published: Nov. 1, 2022

Language: Английский

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5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:Standards of Care in Diabetes—2023

Diabetes Care, Journal Year: 2022, Volume and Issue: 46(Supplement_1), P. S68 - S96

Published: Dec. 12, 2022

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide components diabetes care, general treatment goals guidelines, tools evaluate quality care. Members ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating Standards annually, or more frequently as warranted. For detailed description standards, statements, reports, well evidence-grading system full list Committee members, please refer Introduction Methodology. Readers who wish comment on invited do so at professional.diabetes.org/SOC.

Language: Английский

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Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity

JAMA Internal Medicine, Journal Year: 2022, Volume and Issue: 182(9), P. 953 - 953

Published: Aug. 8, 2022

Importance

It is unclear how effective intermittent fasting for losing weight and body fat, the effects may depend on timing of eating window. This randomized trial compared time-restricted (TRE) with over a period 12 or more hours while matching weight-loss counseling across groups.

Objective

To determine whether practicing TRE by early in day (eTRE) loss, fat cardiometabolic health than hours.

Design, Setting, Participants

The study was 14-week, parallel-arm, clinical conducted between August 2018 April 2020. Participants were adults aged 25 to 75 years obesity who received treatment through Weight Loss Medicine Clinic at University Alabama Birmingham Hospital.

Interventions

All participants (energy restriction [ER]) eTRE plus ER (8-hour window from 7:00 15:00) control (CON) (≥12-hour window).

Main Outcomes Measures

co–primary outcomes loss loss. Secondary included blood pressure, heart rate, glucose levels, insulin plasma lipid levels.

Results

Ninety enrolled (mean [SD] mass index, 39.6 [6.7]; age, 43 [11] years; 72 [80%] female). eTRE+ER group adhered 6.0 (0.8) days per week. intervention (−2.3 kg; 95% CI, −3.7 −0.9 kg;P = .002) but did not affect (−1.4 −2.9 0.2 .09) ratio (−4.2%; −14.9 6.5%;P .43). equivalent reducing calorie intake an additional 214 kcal/d. also improved diastolic pressure (−4 mm Hg; −8 0 Hg;P .04) mood disturbances, including fatigue-inertia, vigor-activity, depression-dejection. other risk factors, food intake, physical activity, sleep similar In secondary analysis 59 completers, trunk CON+ER.

Conclusions Relevance

this trial, improving 14 weeks.

Trial Registration

ClinicalTrials.gov Identifier:NCT03459703

Language: Английский

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5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes—2024

Diabetes Care, Journal Year: 2023, Volume and Issue: 47(Supplement_1), P. S77 - S110

Published: Dec. 11, 2023

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide components diabetes care, general treatment goals guidelines, tools evaluate quality care. Members ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating Standards annually, or more frequently as warranted. For a detailed description standards, statements, reports, well evidence-grading system full list Committee members, please refer Introduction Methodology. Readers who wish comment on invited do so at professional.diabetes.org/SOC.

Language: Английский

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Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial

Cell Metabolism, Journal Year: 2022, Volume and Issue: 34(10), P. 1442 - 1456.e7

Published: Oct. 1, 2022

Over a quarter of the workforce in industrialized countries does shift work, which increases risk for cardiometabolic disease. Yet workers are often excluded from lifestyle intervention studies to reduce this risk. In randomized control trial with 137 firefighters who work 24-h shifts (23-59 years old, 9% female), 12 weeks 10-h time-restricted eating (TRE) was feasible, TRE participants decreasing their window (baseline, mean 14.13 h, 95% CI 13.78-14.47 h; intervention, 11.13 10.73-11.54 p = 3.29E-17) no adverse effects, and improved quality life assessed via SF-36 (ClinicalTrials.gov: NCT03533023). Compared standard care (SOC) arm, significantly decreased VLDL particle size. elevated risks at baseline, there were significant reductions compared SOC glycated hemoglobin A1C diastolic blood pressure. For individuals working schedule, is feasible can improve health, especially increased VIDEO ABSTRACT.

Language: Английский

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Dietary regulation in health and disease

Signal Transduction and Targeted Therapy, Journal Year: 2022, Volume and Issue: 7(1)

Published: July 23, 2022

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences in molecular medicine and clinical trials demonstrated that adequate nutrition treatments are the golden criterion for extending healthspan delaying ageing various species such as yeast, drosophila, rodent, primate human. It emerges develop precision-nutrition therapeutics slow age-related biological processes treat diverse diseases. However, nutritive advantages frequently diversify among individuals well organs tissues, which brings challenges this field. In review, we summarize different forms of dietary interventions extensively prescribed improvement disease treatment pre-clinical or clinical. We discuss nutrient-mediated mechanisms including metabolic regulators, metabolism pathways, epigenetic circadian clocks. Comparably, describe diet-responsive effectors by influence endocrinic, immunological, microbial neural states responsible improving health preventing multiple diseases humans. Furthermore, expatiate patterns dietotheroapies, fasting, calorie-restricted diet, ketogenic high-fibre plants-based protein restriction diet with specific reduction amino acids microelements, potentially affecting morbid states. Altogether, emphasize profound nutritional therapy, highlight crosstalk explored critical factors individualized therapeutic approaches predictors.

Language: Английский

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Developing dietary interventions as therapy for cancer

Nature reviews. Cancer, Journal Year: 2022, Volume and Issue: 22(8), P. 452 - 466

Published: May 25, 2022

Language: Английский

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Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension

Journal of Hypertension, Journal Year: 2023, Volume and Issue: 42(1), P. 23 - 49

Published: Sept. 12, 2023

Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic (DBP) at least 90 (International Society of Hypertension guidelines), affects over 1.5 billion people worldwide. is associated with increased risk cardiovascular disease (CVD) events (e.g. coronary heart disease, failure and stroke) death. An international panel experts convened by the International College Experts compiled lifestyle management recommendations first-line strategy to prevent control hypertension in adulthood. We also recommend that changes be continued even when pressure-lowering medications are prescribed. Specific based on literature evidence summarized advice start these measures early life, including maintaining a healthy body weight, levels different types physical activity, eating drinking, avoidance cessation smoking alcohol use, stress sleep levels. discuss relevance specific approaches consumption sodium, potassium, sugar, fibre, coffee, tea, intermittent fasting well integrated strategies implement using, for example, behaviour change-related technologies digital tools.

Language: Английский

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Obesity in South and Southeast Asia—A new consensus on care and management

Obesity Reviews, Journal Year: 2022, Volume and Issue: 24(2)

Published: Dec. 1, 2022

Obesity is a chronic disease in which the abnormal or excessive accumulation of body fat leads to impaired health and increased risk mortality complications. Prevalence obesity rising rapidly South Southeast Asia, with potentially serious consequences for local economies, healthcare systems, quality life. Our group specialists from Bangladesh, Brunei Darussalam, India, Indonesia, Malaysia, Philippines, Singapore, Sri Lanka, Thailand, Viet Nam undertook develop consensus recommendations management care adults children Asia. To this end, we identified researched 12 clinical questions related obesity. These address optimal approaches identifying staging obesity, treatment (lifestyle, behavioral, pharmacologic, surgical options) maintenance reduced weight, as well issues weight stigma patient engagement setting. We achieved on 42 that these questions. An algorithm describing presented, keyed various recommendations.

Language: Английский

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Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population

Annals of Internal Medicine, Journal Year: 2023, Volume and Issue: 176(7), P. 885 - 895

Published: June 26, 2023

Time-restricted eating (TRE), without calorie counting, has become a popular weight loss strategy, yet long-term randomized trials evaluating its efficacy are limited.

Language: Английский

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