Urinary Concentrations of Bisphenols and Their Association with Biomarkers of Oxidative Stress in People Living Near E-Waste Recycling Facilities in China

Environmental Science & Technology, Journal Year: 2016, Volume and Issue: 50(7), P. 4045 - 4053

Published: March 14, 2016

In this study, concentrations of bisphenol A (BPA) and seven other bisphenols (BPs) were measured in urine samples collected from people living around e-waste dismantling facilities, matched reference population rural urban areas China. BPA, S (BPS), F (BPF) frequently detected (detection frequencies: > 90%) individuals who live near with geometric mean (GM) 2.99 (or 3.75), 0.361 0.469), 0.349 0.435) ng/mL μg/g Cre), respectively; the five BPs rarely found samples, regardless sampling location. The urinary BPA BPF, but not BPS, significantly higher recycling locations than did a Our findings indicated that activities contribute to human exposure BPF. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) was as marker oxidative stress. location, 8-OHdG positively correlated (p < 0.001) BPF; similar correlation also observed sites. These suggest BPS exposures are associated elevated

Language: Английский

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The occurrence, potential toxicity, and toxicity mechanism of bisphenol S, a substitute of bisphenol A: A critical review of recent progress

Ecotoxicology and Environmental Safety, Journal Year: 2019, Volume and Issue: 173, P. 192 - 202

Published: Feb. 14, 2019

Language: Английский

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Low‐Dose Bisphenol A Exposure: A Seemingly Instigating Carcinogenic Effect on Breast Cancer

Advanced Science, Journal Year: 2016, Volume and Issue: 4(2)

Published: Nov. 21, 2016

Breast cancer is the fifth most common cause of death in world and second fatal women. Epidemiological studies clinical data have indicated that hormones, including estrogen, progesterone, prolactin, play important roles initiation progression breast cancer. Bisphenol A (BPA) one commonly used thoroughly studied endocrine disruptors. It can be released from consumer products deposited environment, thus creating potential for human exposure through oral, inhaled, dermal routes. Some recent reviews summarized known mechanisms disruptions by BPA diseases, obesity, reproductive disorders, birth defects. However, large knowledge gaps still exist on may development. Evidence animal vitro has suggested an association between increased incidence at doses below safe reference are environmentally relevant. Most current paid little attention to cancer‐promoting properties low doses. In this review, findings carcinogenic effects low‐dose discussed possible biologic summarized.

Language: Английский

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A critical review of synthetic chemicals in surface waters of the US, the EU and China

Environment International, Journal Year: 2019, Volume and Issue: 131, P. 104994 - 104994

Published: July 11, 2019

There is a wide concern that emerging organic pollutants (EOPs) in surface water could adversely affect human health and wildlife. However, the geographic distribution, exposure pattern ecological risk of are poorly understood at global scale. This paper provides comprehensive survey on level EOPs China, US EU based published literature. The hazard three categories EOPs, namely pharmaceuticals personal care products (PPCPs), pesticides industrial chemicals was further evaluated by adopting novel Aquatic HazPi index jointly accounts for persistence, bioaccumulation, toxicity bioactivity. Furthermore, correlation analysis land use with status regarding synthetic conducted. According to data reported between 2010 2016, concentration higher than China. PPCPs generally lower both while China US. Among whose median >10 ng/L, antiretroviral Efavirenz, pesticide Fipronil, octocrylene, an chemical cosmetic ingredient, were found highest aquatic value. Lastly, spatial distribution hazardous shown depend local landscape usages. Our study first broad overview major economic entities: EU.

Language: Английский

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Endocrine disruptors and the future of toxicology testing — lessons from CLARITY–BPA

Nature Reviews Endocrinology, Journal Year: 2019, Volume and Issue: 15(6), P. 366 - 374

Published: March 6, 2019

Language: Английский

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Insights into removal mechanisms of bisphenol A and its analogues in municipal wastewater treatment plants

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 692, P. 107 - 116

Published: July 10, 2019

Language: Английский

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The Impact of Environmental Chemicals on the Gut Microbiome

Toxicological Sciences, Journal Year: 2020, Volume and Issue: 176(2), P. 253 - 284

Published: May 5, 2020

Abstract Since the surge of microbiome research in last decade, many studies have provided insight into causes and consequences changes gut microbiota. Among multiple factors involved regulating microbiome, exogenous such as diet environmental chemicals been shown to alter significantly. Although substantially contributes are major contaminants our food often overlooked. Herein, we summarize current knowledge on classes (bisphenols, phthalates, persistent organic pollutants, heavy metals, pesticides) their impact which includes alterations microbial composition, gene expression, function, health effects host. We then discuss health-related implications changes, include metabolism, immunity, neurological function.

Language: Английский

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Bisphenol S in Food Causes Hormonal and Obesogenic Effects Comparable to or Worse than Bisphenol A: A Literature Review

Nutrients, Journal Year: 2020, Volume and Issue: 12(2), P. 532 - 532

Published: Feb. 19, 2020

In recent years, bisphenol analogues such as S (BPS) have come to replace A in food packaging and containers, since (BPA) has been shown leach into water, causing numerous negative health effects. Unfortunately, little or no research was done determine the safety of these BPA-free products before they were marketed public a healthier alternative. The latest studies that some may be even more harmful than original BPA situations. This article used literature survey investigate analogue BPS compare it other with regards increased obesity, metabolic disorders, cancer, reproductive defects; among others. It found works via different pathways does while equivalent obesogenic effects, activating preadipocytes, correlated gestational diabetes, not with. also toxic system hormonally promote certain breast cancers at same rate BPA. Therefore, strong argument made regulate exactly manner

Language: Английский

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Bisphenols in water: Occurrence, effects, and mitigation strategies

Chemosphere, Journal Year: 2023, Volume and Issue: 328, P. 138560 - 138560

Published: March 31, 2023

Language: Английский

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Design of magnetic multivariate metal–organic framework for high-efficient adsorption and rapid magnetic separation of bisphenol pollutants

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 475, P. 146459 - 146459

Published: Oct. 5, 2023

Language: Английский

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