A scoping review of human pathogens detected in untreated human wastewater and sludge DOI Creative Commons
Tricia Corrin, Prakathesh Rabeenthira, Kaitlin M. Young

et al.

Journal of Water and Health, Journal Year: 2024, Volume and Issue: 22(2), P. 436 - 449

Published: Jan. 16, 2024

Abstract Wastewater monitoring is an approach to identify the presence or abundance of pathogens within a population. The objective this scoping review (ScR) was and characterize research on human antimicrobial resistance detected in untreated wastewater sludge. A search conducted up March 2023 standard ScR methodology followed. This included 1,722 articles, which 56.5% were published after emergence COVID-19. Viruses bacteria commonly investigated, while protozoa, helminths, fungi infrequent. Articles prior 2019 dominated by transmitted through fecal–oral waterborne pathways, whereas more recent articles have explored detection other pathways such as respiratory vector-borne. There variation sampling, samples, sample processing across studies. current evidence suggests that could be applied range public health tool detect emerging pathogen understand burden spread disease inform decision-making. Further development refinement methods interpret signals for different prioritized are needed develop standards when, why, how monitor effectively.

Language: Английский

Critical Needs for Integrated Surveillance: Wastewater-Based and Clinical Epidemiology in Evolving Scenarios with Lessons Learned from SARS-CoV-2 DOI Creative Commons
Annalaura Carducci, Ileana Federigi,

Giulia Lauretani

et al.

Food and Environmental Virology, Journal Year: 2024, Volume and Issue: 16(1), P. 38 - 49

Published: Jan. 2, 2024

Abstract During the COVID-19 pandemic, wastewater-based epidemiology (WBE) and clinical surveillance have been used as tools for analyzing circulation of SARS-CoV-2 in community, but both approaches can be strongly influenced by some sources variability. From challenging perspective integrating environmental data, we performed a correlation analysis between concentrations raw sewage incident cases areas served medium-size wastewater treatment plants (WWTPs) from 2021 to 2023. To this aim, datasets were adjusted several variability: WBE data factors including analytical protocol, flow, population size, while adjustments considered demographic composition population. Then, addressed impact on differences among sewerage networks variations frequency type swab tests due changes political regulatory scenarios. Wastewater significantly correlated when restrictive containment measures limited movements effect ( ρ = 0.50) confirmed exclusively through molecular testing 0.49). Moreover, positive (although weak) arose WWTPs located densely populated 0.37) with shorter lengths 0.28). This study provides methodological interpreting which could also useful other infections. Data evaluation possible bias need carefully integrated

Language: Английский

Citations

8

Integrating wastewater and randomised prevalence survey data for national COVID surveillance DOI Creative Commons
Guangquan Li, Peter J. Diggle, Marta Blangiardo

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: March 1, 2024

Abstract During the COVID-19 pandemic, studies in a number of countries have shown how wastewater can be used as an efficient surveillance tool to detect outbreaks at much lower cost than traditional prevalence surveys. In this study, we consider utilisation data post-pandemic setting, which collection health via national randomised surveys will likely run reduced scale; hence affordable ongoing system need combine sparse with non-traditional disease metrics such measurements order estimate progression cost-effective manner. Here, use collected during pandemic model dynamic relationship between spatially granular viral load and prevalence. We then nowcast local under scenario that (i) continue collected; (ii) direct are only available coarser spatial resolution, for example or regional scale. The results from our cross-validation study demonstrate added value improving accuracy reducing uncertainty. Our also highlight importance incorporating scale when nowcasting fine calling maintain some form reduced-scale non-epidemic periods. framework is disease-agnostic could therefore adapted different diseases incorporated into multiplex early detection emerging outbreaks.

Language: Английский

Citations

8

A simple SEIR-V model to estimate COVID-19 prevalence and predict SARS-CoV-2 transmission using wastewater-based surveillance data DOI Creative Commons
Tin Phan, Samantha Brozak, Bruce Pell

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 857, P. 159326 - 159326

Published: Oct. 8, 2022

Language: Английский

Citations

36

Wastewater surveillance of SARS-CoV-2 in dormitories as a part of comprehensive university campus COVID-19 monitoring DOI
Emily Lu,

Yuehan Ai,

Angela Davis

et al.

Environmental Research, Journal Year: 2022, Volume and Issue: 212, P. 113580 - 113580

Published: June 6, 2022

Language: Английский

Citations

33

Simple methods for early warnings of COVID-19 surges: Lessons learned from 21 months of wastewater and clinical data collection in Detroit, Michigan, United States DOI Open Access
Liang Zhao,

Yangyang Zou,

Randy E. David

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 864, P. 161152 - 161152

Published: Dec. 23, 2022

Language: Английский

Citations

29

Wastewater surveillance of SARS-CoV-2 at intra-city level demonstrated high resolution in tracking COVID-19 and calibration using chemical indicators DOI Open Access
Prakit Saingam, Bo Li, Bao Nguyen Quoc

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 866, P. 161467 - 161467

Published: Jan. 7, 2023

Language: Английский

Citations

18

Evaluating acute gastroenteritis-causing pathogen reduction in wastewater and the applicability of river water for wastewater-based epidemiology in the Kathmandu Valley, Nepal DOI
Niva Sthapit, Bikash Malla, Sarmila Tandukar

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 919, P. 170764 - 170764

Published: Feb. 7, 2024

Language: Английский

Citations

7

Wastewater based epidemiology as a public health resource in low- and middle-income settings. DOI Creative Commons
Katie Hamilton, Matthew J. Wade, Kayla G. Barnes

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 351, P. 124045 - 124045

Published: April 25, 2024

In the face of emerging and re-emerging diseases, novel innovative approaches to population scale surveillance are necessary for early detection quantification pathogens. The last decade has seen rapid development wastewater environmental (WES) address public health challenges, which led establishment wastewater-based epidemiology (WBE) being deployed monitor a range hazards. WBE exploits fact that excretions secretions from urine, gut discharged in wastewater, particularly sewage, such sampling sewage systems provides an warning system disease outbreaks by providing indication pathogen circulation. While been mainly used locations with networked systems, here we consider its value less connected populations typical lower-income settings, assess opportunity afforded pit latrines sample communities localities. We propose where struggle access diagnostic facilities, despite several additional unconnected remains important means large relatively cost-effective manner.

Language: Английский

Citations

7

Wastewater surveillance for viral pathogens: A tool for public health DOI Creative Commons
Matheus Carmo dos Santos,

Ana Clara Cerqueira Silva,

Carine dos Reis Teixeira

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33873 - e33873

Published: June 29, 2024

A focus on water quality has intensified globally, considering its critical role in sustaining life and ecosystems. Wastewater, reflecting societal development, profoundly impacts public health. Wastewater-based epidemiology (WBE) emerged as a surveillance tool for detecting outbreaks early, monitoring infectious disease trends, providing real-time insights, particularly vulnerable communities. WBE aids tracking pathogens, including viruses, sewage, offering comprehensive understanding of community health lifestyle habits. With the rise global COVID-19 cases, gained prominence, aiding SARS-CoV-2 levels worldwide. Despite advancements treatment, poorly treated wastewater discharge remains threat, amplifying spread water-, sanitation-, hygiene (WaSH)-related diseases. WBE, serving complementary surveillance, is pivotal community-level viral infections. However, there untapped potential to expand surveillance. This review emphasizes importance link between health, highlighting need further integration into management.

Language: Английский

Citations

7

Leveraging an established neighbourhood-level, open access wastewater monitoring network to address public health priorities: a population-based study DOI Creative Commons
Devin A. Bowes, Erin M. Driver, Simona Kraberger

et al.

The Lancet Microbe, Journal Year: 2022, Volume and Issue: 4(1), P. e29 - e37

Published: Dec. 6, 2022

Language: Английский

Citations

27