FEMS Microbiology Reviews,
Journal Year:
2021,
Volume and Issue:
45(4)
Published: Jan. 8, 2021
ABSTRACT
During
the
first
3
years
of
life,
microbial
ecosystem
within
human
gut
undergoes
a
process
that
is
unlike
what
happens
in
this
at
any
other
time
our
life.
This
period
considered
highly
important
developmental
window,
where
microbiota
much
less
resilient
and
more
responsive
to
external
environmental
factors
than
seen
adult
gut.
While
advanced
bioinformatics
clinical
correlation
studies
have
received
extensive
focus
microbiome,
basic
growth
physiology
has
attracted
attention,
although
it
plays
pivotal
role
understand
developing
during
early
In
review,
we
will
thus
take
ecology
perspective
on
analysis
influence
temporal
development
infant
microbiota.
Such
include
sources
microbes
seed
intestinal
environment,
physico-chemical
(abiotic)
conditions
influencing
availability
nutrients
needed
by
microbes.
Nutrients,
Journal Year:
2020,
Volume and Issue:
12(4), P. 1039 - 1039
Published: April 9, 2020
Human
breast
milk
is
considered
the
optimum
feeding
regime
for
newborn
infants
due
to
its
ability
provide
complete
nutrition
and
many
bioactive
health
factors.
Breast
associated
with
improved
infant
immune
development,
less
incidences
of
gastrointestinal
disease
lower
mortality
rates
than
formula
fed
infants.
As
well
as
providing
fundamental
nutrients
growing
infant,
a
source
commensal
bacteria
which
further
enhance
by
preventing
pathogen
adhesion
promoting
gut
colonisation
beneficial
microbes.
While
was
initially
sterile
fluid
microbes
isolated
were
contaminants,
it
now
widely
accepted
that
home
own
unique
microbiome.
The
origins
in
have
been
subject
much
debate,
however,
possibility
an
entero-mammary
pathway
allowing
transfer
from
maternal
mammary
gland
one
potential
pathway.
derived
strains
can
be
regarded
probiotics;
therefore,
studies
focused
on
isolating
subsequent
use
markets.
This
review
aims
discuss
development
preparation
lactation
explore
microbial
composition
human
microbiota
focus
probiotic
development.
Frontiers in Immunology,
Journal Year:
2022,
Volume and Issue:
13
Published: April 5, 2022
Breastfeeding
is
associated
with
long-term
wellbeing
including
low
risks
of
infectious
diseases
and
non-communicable
such
as
asthma,
cancer,
autoimmune
obesity
during
childhood.
In
recent
years,
important
advances
have
been
made
in
understanding
the
human
breast
milk
(HBM)
composition.
Breast
components
as,
non-immune
immune
cells
bioactive
molecules,
namely,
cytokines/chemokines,
lipids,
hormones,
enzymes
reportedly
play
many
roles
breastfed
newborns
mothers,
by
protection
shaping
system
newborn.
Bioactive
HBM
are
also
involved
tolerance
appropriate
inflammatory
response
infants
if
necessary.
This
review
summarizes
current
literature
on
relationship
between
mother
her
infant
through
regard
to
disease
protection.
We
will
shed
some
light
mechanisms
underlying
maintenance
health
both
child
mother.
Gut Microbes,
Journal Year:
2023,
Volume and Issue:
15(1)
Published: April 13, 2023
Exclusive
breastfeeding
is
recommended
for
the
first
six
months
of
life,
but
many
infants
receive
pumped
milk,
formula,
donor
human
or
other
nutritional
sources
during
this
critical
period.
Substantive
evidence
shows
early
nutrition
influences
development
microbiome
and
immune
system,
affecting
lifelong
health.
However,
underlying
mechanisms
are
unclear
nuances
milk
feeding
rarely
considered.
This
review
synthesizes
from
studies
model
systems
to
discuss
impact
different
on
co-development
gut
microbiome,
antigen
tolerance,
immunity.
We
highlight
two
key
mechanisms:
epigenetics
so-called
"weaning
reaction".
Collectively,
highlights
i)
fundamental
role
parents'
own
fed
directly
at
breast,
as
a
dynamic
personalized
source
that
drives
developmental
programming,
ii)
deficiencies
alternative
priority
research
areas
improving
these
alternatives
when
direct
not
possible.
Nutrition in Clinical Practice,
Journal Year:
2020,
Volume and Issue:
35(3), P. 386 - 405
Published: April 24, 2020
Abstract
The
early‐life
microbiome
is
gaining
appreciation
as
a
major
influencer
in
human
development
and
long‐term
health.
Multiple
factors
are
known
to
influence
the
initial
colonization,
development,
function
of
neonatal
gut
microbiome.
In
addition,
alterations
microbial
composition
associated
with
several
chronic
health
conditions
such
obesity,
asthma,
allergies.
this
review,
we
focus
on
both
maternal
infant
colonization.
Also
reviewed
important
role
feeding,
including
evidence‐based
strategies
for
supplementation
goal
protect
and/or
restore
Nutrients,
Journal Year:
2021,
Volume and Issue:
13(3), P. 1026 - 1026
Published: March 22, 2021
Breast
milk
is
an
unbeatable
food
that
covers
all
the
nutritional
requirements
of
infant
in
its
different
stages
growth
up
to
six
months
after
birth.
In
addition,
breastfeeding
benefits
both
maternal
and
child
health.
Increasing
knowledge
has
been
acquired
regarding
composition
breast
milk.
Epidemiological
studies
epigenetics
allow
us
understand
possible
lifelong
effects
breastfeeding.
this
review
we
have
compiled
some
components
with
clear
functional
activity
are
present
human
processes
through
which
they
promote
development
maturation
as
well
modulate
immunity.
Milk
fat
globule
membrane,
proteins,
oligosaccharides,
factors,
exosomes,
or
microorganisms
use
formulas,
any
other
products,
supplements,
nutraceuticals,
even
for
new
clinical
therapies.
The
evaluation
these
compounds
their
commercial
exploitation
limited
by
difficulty
isolating
producing
them
on
adequate
scale.
work
focus
produced
using
from
species
such
bovine,
transgenic
cattle
capable
expressing
microbial
culture
engineering.
