Journal of Child & Adolescent Trauma,
Journal Year:
2024,
Volume and Issue:
18(1), P. 11 - 21
Published: Dec. 6, 2024
Abstract
This
study
aimed
to
a)
discuss
the
neurobiological
mechanisms
of
depersonalization
as
arising
from
activation
at
brainstem
level
and
b)
assess
effectiveness
deep
brain
reorienting
psychotherapy
(DBR)
with
a
patient
presenting
depersonalization-derealization
disorder
(DDD).
In
first
part
paper,
we
verbal
abuse
severe
form
relational
trauma
how
it
can
be
connected
depersonalization.
It
is
argued
that
suddenly
aversive
experiences
engage
locus
coeruleus
in
widespread
noradrenergic
thalamus
cortex
such
balance
functioning
within
becomes
disturbed
subjective
experience
chronic
results.
second
part,
single-case
aims
provide
initial
evidence
experienced
responded
DBR
therapy.
Pre-
post-treatment
measures
consisted
instruments
measure
depersonalization,
social
anxiety
symptoms
quality
life.
After
43
sessions,
participant's
comorbid
decreased
significantly.
Patients
DDD
may
benefit
DBR.
Future
research
required
address
generalizability
larger
population.
Frontiers in Human Neuroscience,
Journal Year:
2024,
Volume and Issue:
18
Published: April 22, 2024
Post-traumatic
stress
disorder
(PTSD)
is
a
heterogeneous
condition
that
affects
many
civilians
and
military
service
members.
Lack
of
engagement,
high
dropout
rate,
variable
response
to
psychotherapy
necessitates
more
compelling
accessible
treatment
options
are
based
on
sound
neuroscientific
evidence-informed
decision-making.
Art
therapy
incorporates
elements
proven
be
effective
in
psychotherapy,
such
as
exposure,
making
it
potentially
valuable
option.
This
conceptual
paper
aims
inform
the
neurophysiological
rationale
for
use
art
therapeutic
approach
individuals
with
PTSD.
A
narrative
synthesis
was
conducted
using
literature
review
empirical
research
effects
therapy,
supporting
neuroaesthetics
psychotherapies
identify
factors
most
pertinent
Findings
were
synthesized
through
proposed
framework
triple
network
model
considering
network-based
dysfunctions
due
therapy’s
active
components,
concretization
metaphor,
emotion
processing
regulation,
perspective
taking
reframing,
alliance,
may
improve
symptoms
PTSD
prompt
adaptive
brain
functioning.
Given
scarcity
rigorous
studies
effectiveness
mechanisms
alleviating
symptoms,
suggested
offers
future
agenda
investigate
impact
Stress,
Journal Year:
2024,
Volume and Issue:
27(1)
Published: May 6, 2024
Although
dysregulated
stress
biology
is
becoming
increasingly
recognized
as
a
key
driver
of
lifelong
disparities
in
chronic
disease,
we
presently
have
no
validated
biomarkers
toxic
physiology;
biological,
behavioral,
or
cognitive
treatments
specifically
focused
on
normalizing
processes;
and
agreed-upon
guidelines
for
treating
the
clinic
evaluating
efficacy
interventions
that
seek
to
reduce
improve
human
functioning.
We
address
these
critical
issues
by
(a)
systematically
describing
systems
mechanisms
are
stress;
(b)
summarizing
indicators,
biomarkers,
instruments
assessing
response
systems;
(c)
highlighting
therapeutic
approaches
can
be
used
normalize
stress-related
biopsychosocial
also
present
novel
multidisciplinary
Stress
Phenotyping
Framework
bring
researchers
clinicians
one
step
closer
realizing
goal
using
precision
medicine-based
prevent
treat
stress-associated
health
problems.
European journal of psychotraumatology,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: Feb. 6, 2025
To
mark
15
years
of
the
European
Journal
Psychotraumatology,
editors
reviewed
past
15-year
research
on
trauma
exposure
and
its
consequences,
as
well
developments
in
(early)
psychological,
pharmacological
complementary
interventions.
In
all
sections
this
paper,
we
provide
perspectives
sex/gender
aspects,
life
course
trends,
cross-cultural/global
systemic
societal
contexts.
Globally,
majority
people
experience
stressful
events
that
may
be
characterized
traumatic.
However,
definitions
what
is
traumatic
are
not
necessarily
straightforward
or
universal.
Traumatic
have
a
wide
range
transdiagnostic
mental
physical
health
limited
to
posttraumatic
stress
disorder
(PTSD).
Research
genetic,
molecular,
neurobiological
influences
show
promise
for
further
understanding
underlying
risk
resilience
trauma-related
consequences.
Symptom
presentation,
prevalence,
course,
response
experiences,
differ
depending
individuals'
age
developmental
phase,
sex/gender,
sociocultural
environmental
contexts,
socio-political
forces.
Early
interventions
potential
prevent
acute
reactions
from
escalating
PTSD
diagnosis
whether
delivered
golden
hours
weeks
after
trauma.
prevention
still
scarce
compared
treatment
where
several
evidence-based
complementary/
integrative
exist,
novel
forms
delivery
become
available.
Here,
focus
how
best
address
negative
outcomes
following
trauma,
serve
individuals
across
spectrum,
including
very
young
old,
include
considerations
ethnicity,
culture
diverse
beyond
Western,
Educated,
Industrialized,
Rich,
Democratic
(WEIRD)
countries.
We
conclude
with
providing
directions
future
aimed
at
improving
well-being
impacted
by
around
world.
The
EJPT
webinar
provides
90-minute
summary
paper
can
downloaded
here
[http://bit.ly/4jdtx6k].
Frontiers in Psychology,
Journal Year:
2025,
Volume and Issue:
16
Published: Feb. 28, 2025
Art
therapy
(AT)
has
been
proposed
as
a
treatment
for
post-traumatic
conditions,
potentially
by
providing
somatic
sensory
input
that
can
(i)
enhance
the
client’s
sense
of
self
and
embodiment,
(ii)
modulate
arousal,
(iii)
aid
in
rethinking
reframing
traumatic
memories.
However,
evidence
supporting
AT
dissociative
disorders
remains
limited.
The
theoretical
basis
efficacy
is
discussed
relation
to
findings
regarding
traumatized
person’s
brain
mindset,
well
its
altered
functional
network
connectivity.
It
crucial
consider
specific
alterations
networks
associated
with
trauma,
particularly
those
occurring
deep
regions,
which
include
midbrain,
brainstem,
cerebellum.
hypothesis
suggests
early
or
severe
trauma
impair
brain’s
higher
regulatory
functions,
explained
cascade
theory.
This
theory
explains
how
diverse
activation
patterns
within
midbrain’s
periaqueductal
gray
(PAG)
midbrain
influence
limbic
system
cortices,
thereby
modulating
states
being
behavior.
Phase-specific,
resource-oriented,
long-term
complexly
individuals
benefit
from
novel
insights
neuroimaging
studies
inform
therapeutic
methods.
illustrated
clinical
vignette
client
diagnosed
identity
disorder
(DID),
where
reorienting
(DBR)
was
combined
relational
AT.
component
hypothesized
have
facilitated
grounding
present
moment
enhanced
access
her
neurophenomenological
self.
Moreover,
changes
may
occurred
at
implicit
non-verbal
levels.
DBR
believed
helped
remain
previously
avoided
unbearable
internal
experience.
To
validate
these
assumptions,
second
author
conducted
semi-structured
interview
focused
on
experiences
psychotherapy
,
including
effect
when
introduced
after
were
articulated
through
thematic
analysis
interview,
yielded
following
themes:
Loneliness,
getting
help
moving
towards
togetherness
.
Further
research
development
methods
neuroplasticity
necessary
highly
clients
change
heal
are
recommended.
Expert Review of Neurotherapeutics,
Journal Year:
2024,
Volume and Issue:
24(3), P. 273 - 289
Published: Feb. 15, 2024
Dissociative
identity
disorder
(DID)
is
a
treatable
mental
health
condition
that
associated
with
range
of
psychobiological
manifestations.
However,
historical
controversy,
modern
day
misunderstanding,
and
lack
professional
education
have
prevented
accurate
treatment
information
from
reaching
most
clinicians
patients.
These
obstacles
also
slowed
empirical
efforts
to
improve
outcomes
for
people
DID.
Emerging
neurobiological
findings
in
DID
provide
essential
can
be
used
outcomes.
Psychology Research and Behavior Management,
Journal Year:
2024,
Volume and Issue:
Volume 17, P. 2403 - 2431
Published: June 1, 2024
Purpose:
Dissociation
is
a
necessary
part
of
our
threat
response
system,
common
to
all
animal
species,
normally
temporarily
activated
under
conditions
extreme
or
inescapable
threat.
Pathological
dissociation,
however,
continues
occur
after
the
initial
has
passed,
in
reminders
inaccessibility
safety
and
security.
Present
across
spectrum
psychiatric
diagnoses,
recurrent
dissociative
symptoms
are
linked
severe
trauma
exposure,
insecure
attachment,
treatment
non-response,
maladaptive
coping
behaviors
such
as
substance
use,
suicidality,
self-harm.
However,
empirical
studies
testing
treatments
specific
processes
remain
scarce.
This
narrative
review
summarizes
existing
provides
theoretical,
neurobiological,
evolutionary
perspectives
on
for
pathological
dissociation.
Methods:
A
systematic
search
five
databases
(MEDLINE,
EMBASE,
APA
PsycINFO,
CINAHL
plus,
Scopus)
was
conducted
April
13,
2023.
Peer-reviewed
clinical
with
adult
participants,
assessing
intervention
effects
symptoms,
were
included.
Results
thematically
analyzed
summarized.
Results:
Sixty-nine
identified,
mainly
focused
posttraumatic
stress
disorder,
trauma-exposed
populations,
borderline
personality
disorder.
Psychotherapy
studied
72.5%
studies;
other
interventions
included
medications
neurostimulation.
The
majority
reported
positive
outcomes,
despite
heterogeneous
interventions.
primary
objective
only
minority.
Conclusion:
dissociation
complex
phenomenon
involving
brain
body
systems
designed
perceiving
responding
threats,
requiring
an
individualized
approach.
literature
emerging
regarding
potentially
evidence-based
help
those
impacted
by
symptoms.
When
contextualized
within
neurobiological
perspective,
these
can
be
understood
facilitating
internal
and/or
relational
sense
safety,
resulting
symptom
reduction.
Further
needed
explore
effective
Keywords:
derealization,
depersonalization,
psychotherapy,
psychopharmacology,
transcranial
magnetic
stimulation
