The Role of Adipokines in Health and Disease

Biomedicines, Journal Year: 2023, Volume and Issue: 11(5), P. 1290 - 1290

Published: April 27, 2023

Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a low-grade state of inflammation and different pathologies. The present review aims analyze the role adipokines in health disease order understand important functions effects these cytokines. For this aim, delves into type adipocytes cytokines produced, as well their functions; relations diseases such cardiovascular, atherosclerosis, mental diseases, metabolic disorders, cancer, eating behaviors; finally, microbiota, nutrition, physical activity is discussed. This information would allow for better understanding on body organisms.

Language: Английский

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Diet strategies for promoting healthy aging and longevity: An epidemiological perspective

Journal of Internal Medicine, Journal Year: 2023, Volume and Issue: 295(4), P. 508 - 531

Published: Oct. 23, 2023

Abstract In recent decades, global life expectancies have risen significantly, accompanied by a marked increase in chronic diseases and population aging. This narrative review aims to summarize findings on the dietary factors influencing longevity, primarily from large cohort studies. First, maintaining healthy weight throughout is pivotal for aging mirroring benefits of lifelong, moderate calorie restriction today's obesogenic food environment. Second, specific types or sources fat, protein, carbohydrates are more important disease risk mortality than their quantity. Third, some traditional diets (e.g., Mediterranean, Nordic, Okinawa) contemporary patterns, such as plant‐based diet index, DASH (dietary approaches stop hypertension) diet, alternate eating been associated with lower longevity. These patterns share many common components predominance nutrient‐rich plant foods; limited red processed meats; culinary herbs spices prevalent cuisines) while embracing distinct elements different cultures. Fourth, combining other lifestyle could extend disease‐free 8–10 years. While adhering core principles diets, it crucial adapt recommendations individual preferences cultures well nutritional needs populations. Public health strategies should aim create healthier environment where nutritious options readily accessible, especially public institutions care facilities elderly. Although further mechanistic studies human trials needed better understand molecular effects aging, there pressing need establish maintain long‐term cohorts studying culturally diverse

Language: Английский

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Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Journal of Translational Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: March 21, 2024

Abstract Over the last decades, Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health undeniable taste that facilitated a widespread popularity. Researchers have investigated role of Mediterranean-type dietary patterns human all around world, reporting consistent findings concerning its benefits. However, what does truly define diet? The myriad scores synthesizes nutritional content diet, but variety aspects are generally unexplored when studying adherence this pattern. Among factors, main characteristics such as consumption fruit vegetables, olive oil, cereals should be accompanied by other underrated features, following: (i) specific reference whole-grain consumption; (ii) considering legumes, nuts, seeds, herbs spices often untested exploring diet; (iii) eggs dairy products common foods consumed in region (irrespectively modern demonization fat intake). Another feature includes (red) wine consumption, more general alcohol intake unmeasured, lacking specificity drinking occasion intensity (i.e., during meals). aspects, cooking methods rather simple yet extremely varied. Several related quality food was first investigated: locally produced, minimally processed, preserved with natural fermentation), strongly connected territory limited controlled impact environment. Dietary habits also associated lifestyle behaviors, sleeping patterns, social cultural values, favoring commensality frugality. In conclusion, it is reductive consider just pattern groups decontextualized from geographical background culture. While methodologies study demonstrated useful up date, holistic approach considered future studies aforementioned features values potentially applied globally through concept “Planeterranean” diet.

Language: Английский

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Public health system sustainability assessment by Gaidai hypersurface approach

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(3), P. 102391 - 102391

Published: Jan. 21, 2024

Language: Английский

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A New Nomenclature for the Very Low-Calorie Ketogenic Diet (VLCKD): Very Low-Energy Ketogenic Therapy (VLEKT). Ketodiets and Nutraceuticals Expert Panels: “KetoNut”, Italian Society of Nutraceuticals (SINut) and the Italian Association of Dietetics and Clinical Nutrition (ADI)

Current Nutrition Reports, Journal Year: 2024, Volume and Issue: 13(3), P. 552 - 556

Published: July 23, 2024

Abstract Purpose of Review In an attempt to clarify the most appropriate nomenclature for very low-calorie ketogenic diets (VLCKD), we propose change and acronym this medical nutrition therapy. The new definition proposed by "KetoNut" panel experts Italian Society Nutraceuticals (SINut) Association Dietetics Clinical Nutrition (ADI) is Very Low-Energy Ketogenic Therapy (VLEKT). Recent Findings last few years, different authors have focused on issue confusion in diets. detail, been differentiated VLCKD that provides < 800 kcal per day, which intended weight loss treatment obesity, a eucaloric diet, contains more calories from fat (predominantly unsaturated) with specific ratios, allow growth children while helping, at same time, establish epileptic seizure control. Summary recent attracted great interest their efficacy epilepsy other neurological diseases but also patients overweight obesity-related metabolic disorders. Nevertheless, although are dietary intervention designed induce nutritional ketosis, macronutrients’ composition called name. may result significant bias mistakes interpretation current scientific evidence. Graphical

Language: Английский

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Planetary Health Diet Index in relation to mortality in a prospective cohort study of U.S. Black females

American Journal of Clinical Nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Prediction of death rates for cardiovascular diseases and cancers

Cancer Innovation, Journal Year: 2023, Volume and Issue: 2(2), P. 140 - 147

Published: Feb. 9, 2023

Abstract Background To estimate cardiovascular and cancer death rates by regions time periods. Design Novel statistical methods were used to analyze clinical surveillance data. Methods A multicenter, population‐based medical survey was performed. Annual recorded deaths from diseases analyzed for all 195 countries of the world. It is challenging model such data; few mathematical models can be applied because disease data are generally not normally distributed. Results novel approach assessing biosystem reliability introduced has been found particularly suitable analyzing multiregion environmental healthcare systems. While traditional temporal observations processes do deal with dimensionality efficiently, our methodology shown able cope this challenge. Conclusions Our public health

Language: Английский

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A Review of Healthy Dietary Choices for Cardiovascular Disease: From Individual Nutrients and Foods to Dietary Patterns

Nutrients, Journal Year: 2023, Volume and Issue: 15(23), P. 4898 - 4898

Published: Nov. 23, 2023

Cardiovascular disease (CVD) remains the first cause of mortality globally. Diet plays a fundamental role in cardiovascular health and is closely linked to development CVD. Numerous human studies have provided evidence on relationship between diet By discussing available findings dietary components that potentially influence CVD progression prevention, this review attempted provide current state healthy choices for We focus effects individual macronutrients, whole food products, patterns risks CVD, data from population-based trials, observational studies, meta-analyses are summarized. Unhealthy habits, such as high intake saturated fatty acids, sugar-sweetened beverages, red meat, processed meat well salt associated with increased risk Conversely, consumption plant-based fiber, nuts, fruits, vegetables shown be effective reducing factors. The Mediterranean appears one most evidence-based beneficial prevention. However, there still great debate regarding whether supplementation vitamins minerals confers cardioprotective benefits. This provides new insights into factors harmful or protective which can adopted improved health.

Language: Английский

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Intercropping Systems: An Opportunity for Environment Conservation within Nut Production

Agriculture, Journal Year: 2024, Volume and Issue: 14(7), P. 1149 - 1149

Published: July 15, 2024

Global population growth and intensive agriculture have both contributed negatively to the environment. As a result, there is increasing interest in use of sustainable alternatives promote better natural resources create an equilibrium between Intercropping, simultaneous cultivation multiple crops, aims optimize land economically while enhancing biodiversity through plant–microorganism interactions, thereby boosting crop productivity. This practice has particularly benefited nut production by combining nutrient-sequestering capacity trees with continuous annual production, improving soil nutrient water utilization. Intercropping systems not only enhance yield quality but also offer economic advantages farmers. review synthesized existing literature aim highlighting positive aspects that intercropping brings nuts, challenges limitations faced different regions when it comes agricultural production.

Language: Английский

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Dietary and lifestyle indices for hyperinsulinemia and odds of MAFLD in overweight and obese children and adolescents

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 6, 2025

Lifestyle and dietary intake play a pivotal role in development of metabolic dysfunction-associated fatty liver disease(MAFLD). We performed this cross-sectional study to evaluate the association between lifestyle insulinemic potential odds MAFLD overweight obese children adolescents. The diet was assessed by computing scores empirical index for hyperinsulinemia(EDIH), hyperinsulinemia(ELIH), insulin resistance(EDIR), resistance(ELIR). diagnosed according consensus definitions. Odds ratios (ORs) 95% confidence intervals (CIs) were calculated logistic regression. A total 334 (49.1% boys) with mean ± SD age BMI-for-age-Z-score 9.3 1.8 2.55 0.69, respectively, enrolled. After adjusting all confounders, participants highest quartile ELIH score had greater developing (OR:3.50;95%CI:1.49–8.22) compared those lowest quartile. This remained significant among boys pubertal ones. However, no EDIH, EDIR, or ELIR found. Our suggests that collective intake, BMI, physical activity is associated increased MAFLD.

Language: Английский

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