Clinical Psychology Review,
Journal Year:
2020,
Volume and Issue:
77, P. 101830 - 101830
Published: Feb. 4, 2020
Mental
disorders
are
highly
complex
and
multifactorial
in
origin,
comprising
an
elaborate
interplay
of
genetic
environmental
factors.
Epigenetic
mechanisms
such
as
DNA
modifications
(e.g.
CpG
methylation),
histone
acetylation)
microRNAs
function
a
translator
between
genes
the
environment.
Indeed,
influences
exposure
to
stress
shape
epigenetic
patterns,
lifetime
experiences
continue
alter
genome
throughout
lifespan.
Here,
we
summarize
recently
burgeoning
body
research
regarding
involvement
aberrant
signatures
mediating
increased
vulnerability
wide
range
mental
disorders.
We
review
current
knowledge
changes
constitute
useful
markers
predicting
clinical
response
psychotherapeutic
interventions,
psychotherapy
-
potentially
reverse
risk
patterns.
Given
first
evidence
pointing
transgenerational
transmission
information,
alterations
arising
from
successful
might
be
transferred
future
generations
thus
contribute
prevention
Findings
integrated
into
multi-level
framework
highlighting
challenges
pertaining
action
implications
research.
Promising
directions
prediction,
prevention,
personalized
treatment
line
with
'precision
medicine'
approach
discussed.
Australian & New Zealand Journal of Psychiatry,
Journal Year:
2015,
Volume and Issue:
49(12), P. 1087 - 1206
Published: Dec. 1, 2015
Objectives:
To
provide
guidance
for
the
management
of
mood
disorders,
based
on
scientific
evidence
supplemented
by
expert
clinical
consensus
and
formulate
recommendations
to
maximise
salience
utility.
Methods:
Articles
information
sourced
from
search
engines
including
PubMed
EMBASE,
MEDLINE,
PsycINFO
Google
Scholar
were
literature
known
disorders
committee
(MDC)
(e.g.,
books,
book
chapters
government
reports)
published
depression
bipolar
disorder
guidelines.
Information
was
reviewed
discussed
members
MDC
findings
then
formulated
into
consensus-based
guidance.
The
guidelines
subjected
rigorous
successive
consultation
external
review
involving:
advisors,
public,
key
stakeholders,
professional
bodies
specialist
groups
with
interest
in
disorders.
Results:
Royal
Australian
New
Zealand
College
Psychiatrists
practice
(Mood
Disorders
CPG)
up-to-date
advice
regarding
that
is
informed
experience.
Mood
CPG
intended
use
psychiatrists,
psychologists,
physicians
others
an
mental
health
care.
Conclusions:
Disorder
first
Clinical
Practice
Guideline
address
both
depressive
It
provides
within
evidence-based
framework,
consensus.
Committee:
Professor
Gin
Malhi
(Chair),
Darryl
Bassett,
Philip
Boyce,
Richard
Bryant,
Paul
Fitzgerald,
Dr
Kristina
Fritz,
Malcolm
Hopwood,
Bill
Lyndon,
Roger
Mulder,
Greg
Murray,
Porter
Associate
Ajeet
Singh.
International
advisors:
Carlo
Altamura,
Francesco
Colom,
Mark
George,
Guy
Goodwin,
McIntyre,
Ng,
John
O’Brien,
Harold
Sackeim,
Jan
Scott,
Nobuhiro
Sugiyama,
Eduard
Vieta,
Lakshmi
Yatham.
Marie-Paule
Austin,
Michael
Berk,
Yulisha
Byrow,
Helen
Christensen,
Nick
De
Felice,
A/Professor
Seetal
Dodd,
Megan
Galbally,
Josh
Geffen,
Hazell,
David
Horgan,
Felice
Jacka,
Gordon
Johnson,
Anthony
Jorm,
Jon-Paul
Khoo,
Jayashri
Kulkarni,
Cameron
Lacey,
Noeline
Latt,
Florence
Levy,
Andrew
Lewis,
Colleen
Loo,
Thomas
Mayze,
Linton
Meagher,
Mitchell,
Daniel
O’Connor,
Tim
Outhred,
Rowe,
Narelle
Shadbolt,
Martien
Snellen,
Tiller,
Watkins,
Raymond
Wu.
Clinical Psychology Review,
Journal Year:
2017,
Volume and Issue:
59, P. 78 - 100
Published: Nov. 10, 2017
Psychological
resilience
refers
to
the
phenomenon
that
many
people
are
able
adapt
challenges
of
life
and
maintain
mental
health
despite
exposure
adversity.
This
has
stimulated
research
on
training
programs
foster
psychological
resilience.
We
evaluated
concepts,
methods
designs
43
randomized
controlled
trials
published
between
1979
2014
which
assessed
efficacy
such
propose
standards
for
future
intervention
based
recent
developments
in
field.
found
current
studies
limited
use
properly
assess
interventions
Major
problems
definitions
as
trait
or
a
composite
factors,
unsuited
assessment
instruments,
inappropriate
study
designs.
To
overcome
these
challenges,
we
1)
an
outcome-oriented
definition
resilience,
2)
change
relation
stressor
load,
3)
methodological
suitable
studies.
Our
proposals
may
contribute
improved
quality
stimulate
further
progress
this
growing
Medicina,
Journal Year:
2019,
Volume and Issue:
55(11), P. 745 - 745
Published: Nov. 16, 2019
Background
and
objectives:
This
paper
addresses
psychological
resilience,
a
multidisciplinary
theoretical
construct
with
important
practical
implications
for
health
sciences.
Although
many
definitions
have
been
proposed
in
several
contexts,
an
essential
understanding
of
the
concept
is
still
lacking
up
to
now.
negatively
affects
comparisons
among
research
results
makes
objective
measurement
difficult.
The
aim
this
review
identify
shared
elements
defining
resilience
across
literature
examined
order
move
toward
conceptual
unification
term.
Materials
methods:
A
was
performed
using
electronic
databases
‘PubMed’
‘PsycINFO’.
Scientific
studies
written
English
between
2002
May
2019
were
included
according
following
key
terms:
‘Psychological’,
‘resilience’,
‘definition’.
Results:
identifies
five
macro-categories
that
summarize
what
has
reported
recent
concerning
phenomenon.
They
serve
as
preliminary
necessary
step
clarification
construct.
Conclusions:
We
propose
definition
ability
maintain
persistence
one’s
orientation
towards
existential
purposes.
It
constitutes
transversal
attitude
can
be
understood
overcome
difficulties
experienced
different
areas
life
perseverance,
well
good
awareness
oneself
own
internal
coherence
by
activating
personal
growth
project.
will
contribute
improving
accuracy
on
topic
suggesting
future
paths
investigation
aimed
at
deeply
exploring
issues
surrounding
promotion
resources.
World Psychiatry,
Journal Year:
2017,
Volume and Issue:
16(2), P. 121 - 129
Published: May 12, 2017
Intriguing
findings
on
genetic
and
environmental
causation
suggest
a
need
to
reframe
the
etiology
of
mental
disorders.
Molecular
genetics
shows
that
thousands
common
rare
variants
contribute
illness.
Epidemiological
studies
have
identified
dozens
exposures
are
associated
with
psychopathology.
The
effect
environment
is
likely
conditional
factors,
resulting
in
gene‐environment
interactions.
impact
factors
also
depends
previous
exposures,
environment‐environment
Most
known
shared
across
multiple
Schizophrenia,
bipolar
disorder
major
depressive
disorder,
particular,
closely
causally
linked.
Synthesis
from
twin
studies,
molecular
epidemiological
research
suggests
joint
consideration
has
much
greater
explanatory
power
than
separate
or
causation.
Multi‐factorial
interactions
be
generic
mechanism
involved
majority
cases
illness,
which
only
partially
tapped
by
existing
studies.
Future
may
cut
psychiatric
disorders
address
poly‐causation
considering
measures
life
course
specific
focus
first
two
decades
life.
Integrative
analyses
including
can
realize
potential
for
discovering
causal
types
mechanisms
generate
new
preventive
therapeutic
tools.
Early Intervention in Psychiatry,
Journal Year:
2018,
Volume and Issue:
13(4), P. 725 - 732
Published: Aug. 20, 2018
Aim
Resilience
is
rapidly
gaining
momentum
in
mental
health
literature.
It
provides
a
new
understanding
of
the
highly
variable
trajectories
illness,
and
has
consistently
been
linked
with
improved
outcomes.
The
present
review
aims
to
clarify
definition
resilience
discuss
directions
for
field.
Methods
After
discussing
resilience,
this
narrative
synthesizes
evidence
that
identifies
specific
protective
factors
involved
process.
This
also
addresses
mechanisms
underlie
resilience.
Results
Recent
literature
clarified
three
core
components
which
are
presence
an
adversity
or
risk
illness;
influence
supersede
risk;
finally,
subsequently
more
positive
outcome
than
expected.
Now
these
largely
agreed
upon,
field
should
move
on
addressing
other
topics.
dynamic
process
by
individuals
utilize
resources
their
benefit.
can
vary
within
one
individual
across
time
circumstance.
refer
good
functional
outcomes
context
diagnosable
illness.
While
previous
research
focused
psychological
it
essential
conceptualized
modalities.
Conclusions
towards
development
multimodal
model
Researchers
now
focus
producing
empirical
clarifies
process,
aligning
concepts
growing,
homogeneous
base,
then
inform
intervention
strategies.
Acta Psychiatrica Scandinavica,
Journal Year:
2013,
Volume and Issue:
129(4), P. 257 - 274
Published: July 3, 2013
This
review
sought
to
identify,
summarise
and
critically
evaluate
studies
that
investigated
attachment
amongst
individuals
with
psychosis.The
following
computerised
databases
searched
were
CINAHL<1980
December
2012;
EMBASE<1980
Ovid
MEDLINE
(R)<1980
PsychINFO<1980
Google
Scholar<1980
2012.We
identified
22
papers
describing
21
comprising
1453
participants,
a
mean
age
of
35.0
years
(range
12-71
years),
whom
68.4%
(n=994)
male.
Of
our
sample,
1112
(76.5%)
had
diagnosis
schizophrenia.
We
found
small
moderate
associations
between
greater
insecurity
(as
reflected
in
anxiety
avoidance)
poorer
engagement
services,
more
interpersonal
problems,
avoidant
coping
strategies,
negative
appraisals
parenting
experiences
severe
trauma.
also
modest
positive
symptoms
affective
symptom
problems.Attachment
theory
may
be
useful
as
means
understanding
the
developmental
basis
recovery
adaptation
context
psychosis.
However,
further
research
representative
samples
their
first
episode
using
prospective
designs
is
required.
PLoS ONE,
Journal Year:
2018,
Volume and Issue:
13(2), P. e0192761 - e0192761
Published: Feb. 13, 2018
Smith
and
colleagues
developed
the
Brief
Resilience
Scale
(BRS)
to
assess
individual
ability
recover
from
stress
despite
significant
adversity.
This
study
aimed
validate
German
version
of
BRS.
We
used
data
a
population-based
(sample
1:
n
=
1.481)
representative
2:
1.128)
sample
participants
general
population
(age
≥
18)
reliability
validity.
Confirmatory
factor
analyses
(CFA)
were
conducted
compare
one-
two-factorial
models
previous
studies
with
method-factor
model
which
especially
accounts
for
wording
items.
Reliability
was
analyzed.
Convergent
validity
measured
by
correlating
BRS
scores
mental
health
measures,
coping,
social
support,
optimism.
good
(α
.85,
ω
.85
both
samples).
The
showed
excellent
fit
χ2/df
7.544;
RMSEA
.07;
CFI
.99;
SRMR
.02;
1.166;
.01;
1.00;
.01)
significantly
better
than
one-factor
(Δχ2(4)
172.71,
p
<
.001)
or
two-factor
(Δχ2(3)
31.16,
.001).
positively
correlated
well-being,
optimism,
coping
strategies
active
positive
reframing,
acceptance,
humor.
It
negatively
somatic
symptoms,
anxiety
insomnia,
dysfunction,
depression,
religion,
denial,
venting,
substance
use,
self-blame.
To
conclude,
our
results
provide
evidence
adaptation
as
well
unidimensional
structure
scale
once
method
effects
are
accounted
for.