Prevalence and risk factors of erectile dysfunction in COVID-19 patients: a systematic review and meta-analysis DOI Open Access
Jihui Zhang, Wei Shi, Min Zou

et al.

Journal of Endocrinological Investigation, Journal Year: 2022, Volume and Issue: 46(4), P. 795 - 804

Published: Oct. 28, 2022

Language: Английский

The Sexual Long COVID (SLC): Erectile Dysfunction as a Biomarker of Systemic Complications for COVID-19 Long Haulers DOI Open Access
Andrea Sansone, Daniele Mollaioli, Erika Limoncin

et al.

Sexual Medicine Reviews, Journal Year: 2021, Volume and Issue: 10(2), P. 271 - 285

Published: Nov. 20, 2021

Language: Английский

Citations

54

The Burden of Hormonal Disorders: A Worldwide Overview With a Particular Look in Italy DOI Creative Commons
Andrea Crafa, Aldo E. Calogero, Rossella Cannarella

et al.

Frontiers in Endocrinology, Journal Year: 2021, Volume and Issue: 12

Published: June 16, 2021

Endocrine diseases have a considerable impact on public health from an epidemiological point of view and because they may cause long-term disability, alteration the quality-of-life affected patients, are fifth leading death. In this extensive review literature, we evaluated prevalence different disorders endocrine interest in world Italy, highlighting their epidemiological, clinical, economic impact.

Language: Английский

Citations

44

Prevalence, Comorbidities, and Risk Factors of Erectile Dysfunction: Results from a Prospective Real-World Study in the United Kingdom DOI Creative Commons
Jim Z. Li,

Terence A. Maguire,

Kelly H. Zou

et al.

International Journal of Clinical Practice, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 10

Published: March 20, 2022

Objectives. Assessment of erectile dysfunction (ED) burden could improve health outcomes associated with underlying cardiometabolic and psychological causes ED. This study provided updated real-world evidence (RWE) on ED epidemiology quantified healthcare resource utilization (HCRU) health-related quality life (HRQoL) among men in the UK. Methods. cross-sectional, prospective was conducted via a self-reported Internet survey 2018 UK general population. Prevalence estimated; HCRU HRQoL were compared between versus without bivariate analysis. Results. Of 12,490 included, 41.5% reported ED; 7.5% severe most prevalent Wales (44.3%). Men older (54.1 ± 14.5 vs. 46.8 14.1 years) often modifiable lifestyle risk factors, including smoking (32.8% 26.3%), drinking alcohol (76.1% 71.0%), not exercising (21.7% 19.4%), being overweight or obese (64.9% 54.6%). Additionally, more ≥1 comorbid chronic conditions (73.7% 47.7%), hypertension (31.8% 16.3%), hyperlipidemia (27.6% 14.0%), depression (24.3% 14.6%), anxiety (23.3% 16.6%), diabetes (15.9% 6.1%) (all, p < 0.001). Nearly half (45.3%) undergoing treatment for comorbidities. Furthermore, visit to physicians/nurse practitioners pharmacists past year had significantly lower SEAR total domain scores than id="M2">p Conclusion. highly affecting over quarter younger men. Cardiometabolic common remained untreated. Higher proportions factors observed present an opportunity providers help mitigate diseases incidence

Language: Английский

Citations

36

Impact of COVID 19 on erectile function DOI Creative Commons

Damilare Hakeem Adeyemi,

Adeyemi Fatai Odetayo, Moses Agbomhere Hamed

et al.

The Aging Male, Journal Year: 2022, Volume and Issue: 25(1), P. 202 - 216

Published: Aug. 4, 2022

Purpose: COVID-19, a novel infection, presented with several complications, including socioeconomical and reproductive health challenges such as erectile dysfunction (ED). The present review summarizes the available shreds of evidence on impact COVID-19 ED.Materials methods: All published peer-reviewed articles from onset outbreak to date, relating ED, were reviewed. Results: Available pieces that ED is consequence are convincing. share common risk factors disruption vascular integrity, cardiovascular disease (CVD), cytokine storm, diabetes, obesity, chronic kidney (CKD). also induces impaired pulmonary haemodynamics, increased ang II, testicular damage low serum testosterone, reduced arginine-dependent NO bioavailability promotes reactive oxygen species (ROS) generation endothelial dysfunction, resulting in ED. In addition, triggers psychological/mental stress suppresses testosterone-dependent dopamine concentration, which contributes incident ED.Conclusions: conclusion, exerts detrimental effect male function, function. This involves cascade events multiple pathways. As pandemic dwindles, identifying long-term effects COVID-19-induced proffering adequate effective measures militating against remains pertinent.

Language: Английский

Citations

36

Impact of COVID-19 on testicular function: a systematic review and meta-analysis DOI Creative Commons
Rossella Cannarella,

Marta Marino,

Andrea Crafa

et al.

Endocrine, Journal Year: 2024, Volume and Issue: 85(1), P. 44 - 66

Published: Feb. 12, 2024

Studies investigating the effects of SARS-CoV-2 on male reproductive function are few and heterogeneous, results often conflicting. This systematic review meta-analysis was carried out studies conducted in men with active or anamnestic infection to evaluate its consequences sex hormone profile semen parameters.

Language: Английский

Citations

7

The Epidemic of COVID-19-Related Erectile Dysfunction: A Scoping Review and Health Care Perspective DOI Creative Commons
Tung‐Chin Hsieh, Natalie C. Edwards, Samir Bhattacharyya

et al.

Sexual Medicine Reviews, Journal Year: 2021, Volume and Issue: 10(2), P. 286 - 310

Published: Sept. 20, 2021

COVID-19 infection is expected to be associated with an increased likelihood of erectile dysfunction (ED). Considering the high transmissibility COVID-19, ED may a concerning consequence for large segment population. To (1) summarize existing published evidence impact on prevalence, severity, treatment, and management ED; (2) identify health-related trends in emerging literature gaps research make recommendations future needs area. A scoping search was conducted April 27, 2021. The Preferred Reporting Items Systematic Reviews Meta-Analyses Extension Scoping (Preferred Meta-Analyses-ScR) checklist followed. performed PubMed using terms: erectile, sexual, dysfunction. total 693 publications were screened relevance. Studies appraised their level based study design rigor methodology. that causes or impacts compelling. Four topics emerged regarding nature association between ED: biological mental health (3) access treatment; (4) disparities ED. Long-term well-designed studies are needed clarify extent pandemic exposed several vulnerabilities within worldwide healthcare social systems. has uniquely harmful men's function through biological, health, mechanisms. As wanes, strategies long-term effects additional care support adequately mitigate health. Hsieh T-C, Edwards NC, Bhattacharyya SK, et al.The Epidemic COVID-19-Related Erectile Dysfunction: Review Health Care Perspective. Sex Med Rev 2022;10:286–310.

Language: Английский

Citations

37

Increased odds ratio for erectile dysfunction in COVID-19 patients DOI Creative Commons
Joseph Katz,

S. Yue,

Wei Xue

et al.

Journal of Endocrinological Investigation, Journal Year: 2021, Volume and Issue: 45(4), P. 859 - 864

Published: Nov. 30, 2021

Language: Английский

Citations

34

COVID-19 and hypopituitarism DOI Creative Commons
Stefano Frara, Paola Loli,

Agnese Allora

et al.

Reviews in Endocrine and Metabolic Disorders, Journal Year: 2021, Volume and Issue: 23(2), P. 215 - 231

Published: Aug. 13, 2021

Besides the pulmonary manifestations caused by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), an emerging endocrine phenotype, which can heavily impact on severity of syndrome, has been recently associated with disease 2019 (COVID-19). Patients pituitary diseases or gland itself may also be involved in COVID-19 clinical presentation and/or severity, causing apoplexy.Moreover, hypopituitarism is frequently burdened several metabolic complications, including arterial hypertension, hyperglycemia, obesity and vertebral fractures, have all poor outcomes increased mortality patients infected SARS-CoV-2.This review will discuss as a condition that might bidirectional relationship due to frequent presence comorbidities, direct indirect damage being per se potential risk factor for COVID-19. Finally, we address current recommendations management vaccines adrenal insufficiency.

Language: Английский

Citations

33

Sexual Health During COVID-19: A Scoping Review DOI Open Access

Nana Ernst Toldam,

Christian Graugaard, Rikke Meyer

et al.

Sexual Medicine Reviews, Journal Year: 2022, Volume and Issue: 10(4), P. 714 - 753

Published: June 29, 2022

Language: Английский

Citations

24

Relationship between hyperuricemia with deposition and sexual dysfunction in males and females DOI Open Access
Andrea Sansone, Yacov Reisman, Emmanuele A. Jannini

et al.

Journal of Endocrinological Investigation, Journal Year: 2022, Volume and Issue: 45(4), P. 691 - 703

Published: Jan. 8, 2022

Language: Английский

Citations

23