Volume Transmission of Neurotransmitters and Neuropeptides in the Brain DOI

Betty Rodríguez Cortés,

Konstantina Chachlaki, Vincent Prévot

et al.

Masterclass in neuroendocrinology, Journal Year: 2025, Volume and Issue: unknown, P. 71 - 100

Published: Jan. 1, 2025

Language: Английский

Nitric Oxide Synthase Inhibition Prevents Cell Proliferation in Glioblastoma DOI

Daniel Kruglyakov,

Shashank Kumar Ojha,

Maryam Kartawy

et al.

Journal of Molecular Neuroscience, Journal Year: 2023, Volume and Issue: 73(11-12), P. 875 - 883

Published: Oct. 16, 2023

Language: Английский

Citations

14

Erectile Function and Sexual Behavior: A Review of the Role of Nitric Oxide in the Central Nervous System DOI Creative Commons
Maria Rosaria Melis, Antonio Argiolas

Biomolecules, Journal Year: 2021, Volume and Issue: 11(12), P. 1866 - 1866

Published: Dec. 11, 2021

Nitric oxide (NO), the neuromodulator/neurotransmitter formed from l-arginine by neuronal, endothelial and inducible NO synthases, is involved in numerous functions across body, control of arterial blood pressure to penile erection, at central level energy homeostasis regulation memory, learning sexual behavior. The aim this work review earlier studies showing that plays a role erectile function behavior hypothalamus its paraventricular nucleus medial preoptic area, integrate these findings with those recent on matter. This revisitation shows influences males females acting not only area but also extrahypothalamic brain areas, often different mechanisms. Most importantly, since areas are strictly interconnected send receive neural projections spinal cord, which communication between genital apparatus takes place, reveals participates concert neurotransmitters/neuropeptides circuit controlling both consummatory (penile copulation, lordosis) appetitive components (sexual motivation, arousal, reward)

Language: Английский

Citations

30

Tanycytes in the infundibular nucleus and median eminence and their role in the blood–brain barrier DOI
Vincent Prévot, Rubén Nogueiras, Markus Schwaninger

et al.

Handbook of clinical neurology, Journal Year: 2021, Volume and Issue: unknown, P. 253 - 273

Published: Jan. 1, 2021

Language: Английский

Citations

28

Nitric oxide involvement in the disability and active disease of multiple sclerosis: Systematic review and meta-analysis DOI
Brenda da Silva, Fernanda Tibolla Viero, Patrícia Rodrigues

et al.

Nitric Oxide, Journal Year: 2024, Volume and Issue: 145, P. 8 - 20

Published: Feb. 6, 2024

Language: Английский

Citations

5

Advances in the Electrophysiological Recordings of Long-Term Potentiation DOI Open Access

Feixu Jiang,

Stephen Temitayo Bello, Qianqian Gao

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(8), P. 7134 - 7134

Published: April 12, 2023

Understanding neuronal firing patterns and long-term potentiation (LTP) induction in studying learning, memory, neurological diseases is critical. However, recently, despite the rapid advancement neuroscience, we are still constrained by experimental design, detection tools for exploring mechanisms pathways involved LTP induction, ability of action signals. This review will reiterate LTP-related electrophysiological recordings mammalian brain nearly 50 years explain how excitatory inhibitory neural results have been detected described field- single-cell potentials, respectively. Furthermore, focus on describing classic model inhibition discuss neuron activity when neurons activated to induce LTP. Finally, propose recording under same conditions combining various technologies novel design suggestions future research. We discussed different types synaptic plasticity, potential astrocytes also deserves be explored future.

Language: Английский

Citations

11

Effects of extended-release 7-nitroindazole gel formulation treatment on the behavior of Shank3 mouse model of autism DOI Creative Commons

Muhammad Abdel-Haq,

Shashank Kumar Ojha,

Wajeha Hamoudi

et al.

Nitric Oxide, Journal Year: 2023, Volume and Issue: 140-141, P. 41 - 49

Published: Sept. 14, 2023

Language: Английский

Citations

11

Changes of Signaling Pathways in Hypothalamic Neurons with Aging DOI Creative Commons
П. М. Маслюков

Current Issues in Molecular Biology, Journal Year: 2023, Volume and Issue: 45(10), P. 8289 - 8308

Published: Oct. 12, 2023

The hypothalamus is an important regulator of autonomic and endocrine functions also involved in aging regulation. process the accompanied by disturbed intracellular signaling including insulin/insulin-like growth factor-1 (IGF-1)/growth hormone (GH), phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (AKT)/the mammalian target rapamycin (mTOR), mitogen activated protein (MAPK), janus (JAK)/signal transducer activator transcription (STAT), AMP-activated (AMPK), nuclear factor kappa-light-chain-enhancer cells (NF-ĸB), nitric oxide (NO). In current review, I have summarized understanding changes above-mentioned pathways with a focus on hypothalamic alterations.

Language: Английский

Citations

10

Changes of nNOS expression in the tuberal hypothalamic nuclei during ageing DOI
K. Yu. Moiseev,

P. A. Vishnyakova,

В. В. Порсева

et al.

Nitric Oxide, Journal Year: 2020, Volume and Issue: 100-101, P. 1 - 6

Published: April 10, 2020

Language: Английский

Citations

25

Interaction among Hydrogen Sulfide and Other Gasotransmitters in Mammalian Physiology and Pathophysiology DOI
Yaqian Huang, Hongfang Jin, Heng Zhang

et al.

Advances in experimental medicine and biology, Journal Year: 2021, Volume and Issue: unknown, P. 205 - 236

Published: Jan. 1, 2021

Language: Английский

Citations

23

Modulation of Heart Rate Variability and Brain Excitability through Acute Whole-Body Vibration: The Role of Frequency DOI Open Access

Jingwang Tan,

Jianbin Lei,

Sam Wu

et al.

Journal of Human Kinetics, Journal Year: 2024, Volume and Issue: 92, P. 111 - 120

Published: April 25, 2024

This cross-over study aimed to explore effects of acute whole-body vibration (WBV) at frequencies 5–35 Hz on heart rate variability and brain excitability. Thirteen healthy physically active college students randomly completed eight interventions under the following conditions: static upright standing without (CON), squat exercise (knee flexion 150°) platform (SSE), combined with WBV frequency 5, 9, 13, 20, 25, 35 Hz. Five bouts × 30 s a 30-s rest interval were performed for all interventions. The brain’s direct current potentials (DCPs), domain variables (FDV) including normalized low power (nLF), high (nHF) ratio LF HF (LF/HF), along mean (MHR) collected calculated before after intervention. Results suggested that 5 had substantial effect decreasing DCPs [−2.13 μV, t(84) = −3.82, p < 0.05, g −1.03, large] nLF [−13%, −2.31, 0.04, −0.62, medium]. By contrast, 20–35 intervention considerably improved [7.58 4.31, 1.16, large], [17%, 2.92, 0.79, LF/HF [0.51, 2.86, 0.77, large]. A strong (r 0.7, 0.01) correlation between was found In summary, principally activated sympathetic nervous system increased excitability, while 5-Hz parasympathetic reduced spectrum might be manipulated according target

Language: Английский

Citations

3