The additive effect of periodontitis with hypertension on risk of systemic disease and mortality DOI
Harriet Larvin, Jing Kang, Vishal R. Aggarwal

et al.

Journal of Periodontology, Journal Year: 2022, Volume and Issue: 93(7), P. 1024 - 1035

Published: April 23, 2022

Abstract Background Recent evidence suggests that periodontitis (PD) causes hypertension, which is a precursor to development of other systemic diseases. The aim this study was examine the effect hypertension and PD on risk subsequent disease. Methods This longitudinal cohort included 244,393 UK Biobank participants who were free disease than at baseline. Self‐reported responses painful gums or loose teeth surrogates for PD. Hypertensives identified by clinical diagnosis, elevated blood pressure (≥140/90 mmHg). Systemic diseases including cancer, cardiovascular (CVD), diabetes from linked diagnostic codes. Multivariable Cox proportional hazard models used quantify all‐cause mortality, stratified hypertensive status. Results average age population 55.4 years (standard deviation [SD:] 8.1 years), 130,220 (53.3%) female. At baseline, 131,566 (53.8%) 4.5% reported incidence rates all higher in non‐hypertensive same In hypertensives, an additive observed risks CVD (adjusted ratio [HR]: 1.35, 95% confidence interval [CI]: 1.21–1.53) respiratory (HR: 1.11, CI: 0.95–1.30) compared healthy controls. Conclusions with have exacerbated several Future interventional studies should consider periodontal treatment outcomes targeted populations.

Language: Английский

Periodontal disease: the portrait of an epidemic DOI Open Access
Riccardo Nocini, Giuseppe Lippi, Camilla Mattiuzzi

et al.

Journal of Public Health and Emergency, Journal Year: 2020, Volume and Issue: 4, P. 10 - 10

Published: June 1, 2020

Background: This article aims to provide updated statistics on worldwide burden of periodontal disease. Methods: An electronic search was carried out in Global Health Data Exchange (GHDx) database, using the keywords "periodontal disease", "metric", "year", "sex", "age" and "location". Search results were imported into a Microsoft Excel file elaborated. Results: Incidence, prevalence disability-adjusted life year (DALYs) disease have constantly increased during past 3 decades, making it 12th more prevalent pathology around world. Women 13% higher risk incident disease, whilst values both these epidemiological measures exponentially increase after 19 years age. The highest is recorded South-East Asia Western Pacific, lowest Africa. Pacific has also displayed largest decades. Conclusions: current estimates concur define portrait growing epidemic.

Language: Английский

Citations

31

Current Knowledge Regarding the Interaction Between Oral Bone Metabolic Disorders and Diabetes Mellitus DOI Creative Commons
Xiaofeng Wang, Huiyu Wang,

Zhang Tian-fu

et al.

Frontiers in Endocrinology, Journal Year: 2020, Volume and Issue: 11

Published: Aug. 7, 2020

Diabetes mellitus, as one of the main chronic diseases affecting human health, has shown an increasing prevalence in recent years. mellitus can cause bone metabolic disorders patients, leading to osteoporosis, a higher risk traumatic fracture, and other diseases. Bone oral cavity principally manifest periodontitis, loss alveolar bone, failure implant osseointegration. In years, numerous studies have that there is complex interaction between diabetes mellitus. This paper reviews adverse effects on metabolism such osteoporosis patients with discusses potential mechanism loss, suggests prevention treatment

Language: Английский

Citations

29

Impact of Poor Oral Health on Community-Dwelling Seniors: A Scoping Review DOI Creative Commons
Rana Badewy, Harkirat Singh, Carlos Quiñonez

et al.

Health Services Insights, Journal Year: 2021, Volume and Issue: 14

Published: Jan. 1, 2021

The aim of this scoping review was to determine health-related impacts poor oral health among community-dwelling seniors. Using MeSH terms and keywords such as elderly, general health, geriatrics, 3 electronic databases—Medline, CINAHL, Age Line were searched. Title abstracts independently screened by reviewers, followed full-texts review. A total 131 articles met our inclusion criteria, the majority these studies prospective cohort (77%, n = 103), conducted in Japan (42 %, 55). These categorized into 16 outcomes, with mortality (24%, 34), mental disorders (21%, 30) being most common outcomes linked health. 90% (n 120) included reported that seniors can subsequently lead a higher risk population. Improving access healthcare services for elderly help not only reduce burden diseases population group but also address morbidity associated other conditions caused due Findings from study identify shortcomings existing programs develop future improve utilization care elderly.

Language: Английский

Citations

27

Multimorbid disease trajectories for people with periodontitis DOI
Harriet Larvin, Jing Kang, Vishal R. Aggarwal

et al.

Journal Of Clinical Periodontology, Journal Year: 2021, Volume and Issue: 48(12), P. 1587 - 1596

Published: Aug. 18, 2021

Periodontitis is a multifactorial condition linked to increased risk of systemic diseases. This study aimed identify disease trajectories people with periodontitis using the process mining technique as heuristic approach.A total 188,863 participants from UK Biobank cohort were included. Self-reported oral health indicators (bleeding gums, painful loose teeth) surrogates for at baseline. Systemic diagnoses and dates formed event log. Relative (RR) diseases, trajectories, Cox proportional hazard ratio models mortality compared age- sex-matched controls who did not report history periodontitis.Participants teeth had shorter median time most crude RR was several diseases including cardiovascular (crude RR: 1.15, 95% CI: 1.03-1.28), hypertension 1.14, 1.05-1.24), depression 1.33, 1.09-1.61). Participants 20 though these significant after adjustments. bleeding/painful gums similar those matched controls.Self-reported may be associated early frequent multimorbidity development, further evidence required confirm this hypothesis. People should informed risks progression targeted in prevention initiatives.

Language: Английский

Citations

25

The additive effect of periodontitis with hypertension on risk of systemic disease and mortality DOI
Harriet Larvin, Jing Kang, Vishal R. Aggarwal

et al.

Journal of Periodontology, Journal Year: 2022, Volume and Issue: 93(7), P. 1024 - 1035

Published: April 23, 2022

Abstract Background Recent evidence suggests that periodontitis (PD) causes hypertension, which is a precursor to development of other systemic diseases. The aim this study was examine the effect hypertension and PD on risk subsequent disease. Methods This longitudinal cohort included 244,393 UK Biobank participants who were free disease than at baseline. Self‐reported responses painful gums or loose teeth surrogates for PD. Hypertensives identified by clinical diagnosis, elevated blood pressure (≥140/90 mmHg). Systemic diseases including cancer, cardiovascular (CVD), diabetes from linked diagnostic codes. Multivariable Cox proportional hazard models used quantify all‐cause mortality, stratified hypertensive status. Results average age population 55.4 years (standard deviation [SD:] 8.1 years), 130,220 (53.3%) female. At baseline, 131,566 (53.8%) 4.5% reported incidence rates all higher in non‐hypertensive same In hypertensives, an additive observed risks CVD (adjusted ratio [HR]: 1.35, 95% confidence interval [CI]: 1.21–1.53) respiratory (HR: 1.11, CI: 0.95–1.30) compared healthy controls. Conclusions with have exacerbated several Future interventional studies should consider periodontal treatment outcomes targeted populations.

Language: Английский

Citations

17