Diabetes Obesity and Metabolism,
Journal Year:
2020,
Volume and Issue:
23(S1), P. 50 - 62
Published: Sept. 24, 2020
Against
the
backdrop
of
obesity
as
a
major
public
health
problem,
we
examined
three
questions:
How
much
weight
loss
is
needed
to
benefit
patients
with
obesity?
well
do
current
therapies
in
producing
loss?
What
strategies
can
be
used
improve
patient
outcomes
using
evidence-based
studies.
This
paper
reviews
literature
on
lifestyle,
diet,
medications
and
surgical
treatments
for
searches
treatments.
Current
treatments,
including
diet
exercise,
produce
5%
7%
average.
Despite
continued
attempts
identify
superior
dietary
approaches,
most
careful
comparisons
find
that
low
carbohydrate
diets
are
not
significantly
better
than
fat
loss.
The
four
currently
approved
by
US
Food
Drug
Administration
long-term
management
effective
surgery,
adding
about
average
lifestyle
approaches
Two
new
under
investigation,
semaglutide
tirzepatide,
this.
For
all
loss,
there
enormous
variability
amount
lost.
Examination
this
has
yielded
evidence
supporting
baseline
process
predictors,
but
effect
sizes
associated
these
predictors
small
no
prospective
studies
showing
personalized
approach
based
genotype
or
phenotype
will
yield
uniform
success.
Because
chronic
disease
it
requires
'continuous
treatment
model'
across
lifespan.
CA A Cancer Journal for Clinicians,
Journal Year:
2020,
Volume and Issue:
70(4), P. 245 - 271
Published: June 9, 2020
Abstract
The
American
Cancer
Society
(ACS)
publishes
the
Diet
and
Physical
Activity
Guideline
to
serve
as
a
foundation
for
its
communication,
policy,
community
strategies
and,
ultimately,
affect
dietary
physical
activity
patterns
among
Americans.
This
guideline
is
developed
by
national
panel
of
experts
in
cancer
research,
prevention,
epidemiology,
public
health,
reflects
most
current
scientific
evidence
related
risk.
ACS
focuses
on
recommendations
individual
choices
regarding
diet
patterns,
but
those
occur
within
context
that
either
facilitates
or
creates
barriers
healthy
behaviors.
Therefore,
this
committee
presents
action
accompany
4
reduce
These
recognize
supportive
social
environment
indispensable
if
individuals
at
all
levels
society
are
have
genuine
opportunities
choose
2020
consistent
with
guidelines
from
Heart
Association
Diabetes
prevention
coronary
heart
disease
diabetes
well
general
health
promotion,
defined
2015
Dietary
Guidelines
Americans
2018
BMJ,
Journal Year:
2018,
Volume and Issue:
unknown, P. k4641 - k4641
Published: Nov. 21, 2018
Abstract
Objectives
To
prospectively
evaluate
the
joint
association
of
duration
rotating
night
shift
work
and
lifestyle
factors
with
risk
type
2
diabetes
risk,
to
quantitatively
decompose
this
only,
their
interaction.
Design
Prospective
cohort
study.
Setting
Nurses’
Health
Study
(1988-2012)
II
(1991-2013).
Participants
143
410
women
without
diabetes,
cardiovascular
disease,
or
cancer
at
baseline.
Exposures
Rotating
was
defined
as
least
three
shifts
per
month
in
addition
day
evening
that
month.
Unhealthy
lifestyles
included
current
smoking,
physical
activity
levels
below
30
minutes
moderate
vigorous
intensity,
diet
bottom
fifths
Alternate
Healthy
Eating
Index
score,
body
mass
index
25
above.
Main
outcome
measures
Incident
cases
were
identified
through
self
report
validated
by
a
supplementary
questionnaire.
Results
During
22-24
years
follow-up,
10
915
incident
occurred.
The
multivariable
adjusted
hazard
ratios
for
1.31
(95%
confidence
interval
1.19
1.44)
five
year
increment
2.30
(1.88
2.83)
unhealthy
factor
(ever
low
quality,
activity,
overweight
obesity).
For
ratio
2.83
(2.15
3.73)
significant
additive
interaction
(P
<0.001).
proportions
17.1%
(14.0%
20.8%)
alone,
71.2%
(66.9%
75.8%)
11.3%
(7.3%
17.3%)
Conclusions
Among
female
nurses,
both
associated
higher
diabetes.
excess
combined
than
each
individual
factor.
These
findings
suggest
most
could
be
prevented
adhering
healthy
lifestyle,
benefits
greater
workers.
International Journal of Epidemiology,
Journal Year:
2018,
Volume and Issue:
47(6), P. 1956 - 1971
Published: April 20, 2018
An
increasing
number
of
original
studies
suggest
that
exposure
to
shift
work
could
be
associated
with
the
risk
overweight
and
obesity,
but
results
remain
conflicted
inconclusive.
This
study
aimed
quantitatively
synthesize
available
epidemiological
evidence
on
association
between
obesity
by
a
meta-analysis.
The
authors
searched
PubMed,
Embase
reference
lists
all
included
up
April
2017,
verification
search
in
December
2017.
Inclusion
criteria
were
reported
odds
ratios,
relative
risks
or
hazard
ratios
(ORs,
RRs
HRs,
respectively)
at
least
one
outcome
obesity.
Summary
estimates
calculated
random-effect
models.
Twenty-six
(7
cohort
studies,
18
cross-sectional
1
case–control
study)
involving
311
334
participants
identified.
Among
these
cut-off
points
varied
greatly,
so
heterogeneity
was
substantial;
however,
stable.
Shift
found
positively
[RR:
1.25;
95%
confidence
interval
(95%
CI):
1.08–1.44]
(RR:
1.17;
CI:
1.12–1.22).
Individuals
involved
are
more
likely
become
obese.
Appropriate
preventive
interventions
organization
schedules
according
ergonomic
would
allow
workers
avoid
potential
health
impairment.