Crystals,
Journal Year:
2022,
Volume and Issue:
12(11), P. 1513 - 1513
Published: Oct. 25, 2022
There
is
a
crucial
necessity
for
the
formulation
of
efficient
antimicrobial
agents
owing
to
increasing
prevalence
hospital-acquired
bacterial
infections
triggered
by
multidrug-resistant
microbes
that
result
in
significant
deaths
and
illnesses
around
world.
Hence,
current
investigation
examined
antibacterial
proficiency
zinc
oxide
nanoparticles
formulated
utilizing
green
route
against
strains
were
resistant
multiple
drugs.
In
addition,
synergistic
action
ZnO
(ZnO
NPs)
combined
with
colistin
was
investigated
tested
microbial
determine
efficiency
bioinspired
boosting
antibiotic.
Incidentally,
synthesized
using
water
extract
Origanum
majorana
leaves
these
nanomaterials
physicochemically
characterized
different
analytical
techniques.
The
bioactivity
appraised
agar
diffusion
method.
biogenic
NPs
at
concentration
100
μg/disk
revealed
compelling
efficacy
strains,
expressing
maximum
Escherichia
coli
strain
clear
zone
diameter
38.16
±
0.18
mm.
remarkable
might
be
accredited
tiny
particle
size
bioformulated
12.467
1.36
nm.
net
charge
−14.8
mV
while
XRD
analysis
confirmed
their
hexagonal
wurtzite
structure.
Furthermore,
showed
promising
potency
demonstrating
respective
synergism
proportions
91.05,
79.07,
75.04,
75.25,
56.28
10.60%
E.
coli,
Klebsiella
pneumoniae,
Acinetobacter
baumannii,
Salmonella
typhimurium,
Enterobacter
cloacae,
Pseudomonas
aeruginosa,
respectively.
conclusion,
O.
mediated
unique
physicochemical
characteristics
effective
drug-resistant
strains.
These
could
used
synthesis
coatings
control
hospital
acquired
caused
pathogens.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(11), P. 4527 - 4527
Published: June 2, 2023
In
the
last
few
decades,
broad
scope
of
nanomedicine
has
played
an
important
role
in
global
healthcare
industry.
Biological
acquisition
methods
to
obtain
nanoparticles
(NPs)
offer
a
low-cost,
non-toxic,
and
environmentally
friendly
approach.
This
review
shows
recent
data
about
several
for
procuring
exhaustive
elucidation
biological
agents
such
as
plants,
algae,
bacteria,
fungi,
actinomycete,
yeast.
When
compared
physical,
chemical,
approaches
obtaining
nanoparticles,
approach
significant
advantages
non-toxicity
environmental
friendliness,
which
support
their
use
therapeutic
applications.
The
bio-mediated,
procured
not
only
help
researchers
but
also
manipulate
particles
provide
health
safety.
addition,
we
examined
biomedical
applications
antibacterial,
antifungal,
antiviral,
anti-inflammatory,
antidiabetic,
antioxidant,
other
medical
highlights
findings
current
research
on
bio-mediated
novel
NPs
scrutinizes
various
proposed
describe
them.
synthesis
from
plant
extracts
advantages,
including
bioavailability,
low
cost.
Researchers
have
sequenced
analysis
biochemical
mechanisms
enzyme
reactions
well
determination
bioactive
compounds
mediated
by
nanoparticle
acquisition.
is
primarily
concerned
with
collating
variety
disciplines
that
frequently
provides
new
clarifications
serious
problems.
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Aug. 21, 2023
Abstract
The
gradual
deterioration
of
the
supporting
periodontal
tissues
caused
by
periodontitis,
a
chronic
multifactorial
inflammatory
disease,
is
thought
to
be
triggered
colonization
dysbiotic
plaque
biofilms
in
vulnerable
host.
One
most
prevalent
dental
conditions
world,
periodontitis
now
leading
factor
adult
tooth
loss.
When
does
develop,
it
treated
scraping
mineralized
deposits
and
biofilm
off
surfaces.
Numerous
studies
have
shown
that
non-surgical
treatment
significantly
improves
clinical
microbiological
indices
individuals
with
periodontitis.
Although
parameters
improved,
certain
bacterial
reservoirs
often
persist
on
root
surfaces
even
after
standard
therapy.
Periodontitis
has
been
local
or
systemic
antibiotics
as
well
scaling
planning.
Since
there
aren't
many
brand-new
market,
several
researchers
are
currently
concentrating
creating
alternate
methods
combating
germs.
There
delay
study
subject
nanoparticle
(NP)
toxicity,
which
especially
concerned
mechanisms
action,
while
area
nanomedicine
develops.
promising
them
metal
NPs
since
they
potent
antibacterial
action.
Metal
may
employed
efficient
growth
inhibitors
variety
bacteria,
making
useful
for
In
this
way,
new
contributed
development
anti-inflammatory
platforms
current
therapeutic
effects
metallic
summarized
study.
This
data
might
used
develop
NP-based
alternatives
infections.
Graphical
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Jan. 5, 2024
Abstract
Periodontitis,
one
of
the
most
prevalent
dental
diseases,
causes
loss
bone
and
gum
tissue
that
hold
teeth
in
place.
Several
bacteria,
commonly
present
clinically
healthy
oral
cavities,
may
induce
perpetuate
periodontitis
when
their
concentration
rises
gingival
sulcus.
Antibacterial
effect
against
various
Gram-negative
Gram-positive
including
pathogenic
drug-resistant
ones,
has
been
shown
for
several
distinct
transient
metal
oxide
NPs.
Therefore,
NPs
be
used
biomedicine
to
treat
periodontal
problems
nanotechnology
inhibit
development
microorganisms.
Instead
using
harmful
chemicals
or
energy-intensive
machinery,
biosynthesis
nanoparticles
(NPs)
suggested.
To
produce
NPs,
ideal
technique
is
“Green”
synthesis
because
its
low
toxicity
safety
human
health
environment.
Gold
(AuNPs)
appear
less
toxic
mammalian
cells
than
other
nanometals
antibacterial
activity
not
dependent
on
reactive
oxygen
species
(ROS).
AgNPs
also
possess
chemical
stability,
catalytic
activity,
superior
electrical
thermal
conductivity,
name
a
few
advantageous
characteristics.
It
was
observed
zinc
(ZnO)
copper
(Cu)
exhibited
discernible
inhibitory
effects
gram-positive
gram-negative
bacterial
strains,
respectively.
ZnO
demonstrated
bactericidal
microorganisms
responsible
periodontitis.
Medications
containing
magnetic
are
highly
effective
multidrug-resistant
fungal
infections.
The
titanium
dioxide
(TiO
2
)
implicated
elevating
salivary
peroxidase
individuals
diagnosed
with
chronic
Furthermore,
specific
metallic
have
potential
enhance
antimicrobial
efficacy
treatments
combined.
these
as
well
only
some
metals
oxides
synthesized
environmentally
friendly
ways
therapeutic
benefits
Graphical
Bioengineering,
Journal Year:
2023,
Volume and Issue:
10(3), P. 327 - 327
Published: March 5, 2023
Silver
nanoparticles
have
been
a
recent
focus
of
many
researchers
in
dentistry,
and
their
potential
uses
benefits
drawn
attention
dentistry
medicine.
The
fabrication
utilization
nanoscale
substances
structures
are
at
the
core
rapidly
developing
areas
nanotechnology.
They
often
used
dental
industry
because
they
prevent
bacteria
from
making
nanoparticles,
oxides,
biofilms.
also
stop
metabolism
bacteria.
(AgNPs)
type
zero-dimensional
material
with
different
shapes.
Dentistry
has
to
keep
up
changing
patient
needs
new
technology.
can
be
for
disinfection
preventing
infections
oral
cavity.
One
most
interesting
metallic
biomedical
applications
is
silver
(AgNPs).
field
found
promising
elimination
plaque
tartar,
as
well
bacterial
fungal
mouth.
incorporation
AgNPs
into
materials
shown
significantly
enhance
patients’
health,
leading
widespread
use.
This
review
focuses
on
AgNP
synthesis,
chemical
properties,
biocompatibility,
various
fields,
biomaterials
dentistry.
With
an
emphasis
aspects
related
inclusion
this
descriptive
paper
intends
address
developments
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(10), P. 1676 - 1676
Published: May 14, 2022
Nanotechnology
utilizes
the
mechanics
to
control
size
and
morphology
of
particles
in
required
nano
range
for
accomplishing
intended
purposes.
There
was
a
time
when
it
predominantly
applied
only
fields
matter
physics
or
chemical
engineering,
but
with
time,
biological
scientists
recognized
its
vast
benefits
explored
advantages
their
respective
fields.
This
extension
nanotechnology
field
dentistry
is
termed
‘Nanodentistry.’
It
revolutionizing
every
aspect
dentistry.
consists
therapeutic
diagnostic
tools
supportive
aids
maintain
oral
hygiene
help
nanomaterials.
Research
nanodentistry
evolving
holistically
slowly
advanced
finding
symbiotic
use
novel
polymers,
natural
metals,
minerals,
drugs.
These
materials,
association
nanotechnology,
further
assist
exploring
usage
dental
adducts
prosthodontic,
regeneration,
orthodontic,
etc.
Moreover,
drug
release
cargo
abilities
adduct
provide
an
extra
edge
over
conventional
counterparts.
Nano
has
expanded
single
branch
In
present
review,
we
will
holistic
view
recent
advances
nanodentistry.
The
later
part
review
compiled
ethical
regulatory
challenges
commercialization
tracks
advancement
different
important
domains