Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects

Atherosclerosis, Journal Year: 2019, Volume and Issue: 292, P. 90 - 98

Published: Nov. 15, 2019

Language: Английский

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Fortification of Human Milk for Preterm Infants: Update and Recommendations of the European Milk Bank Association (EMBA) Working Group on Human Milk Fortification

Frontiers in Pediatrics, Journal Year: 2019, Volume and Issue: 7

Published: March 22, 2019

Evidence indicates that human milk (HM) is the best form of nutrition uniquely suited not only to term but also preterm infants conferring health benefits in both short and long-term. However, HM does provide sufficient for very low birth weight (VLBW) infant when fed at usual feeding volumes leading slow growth with risk neurocognitive impairment other poor outcomes such as retinopathy bronchopulmonary dysplasia. should be supplemented (fortified) nutrients supply, particularly protein, calcium, phosphate meet high requirements this group babies. In paper European Milk Bank Association (EMBA) Working Group on Fortification discusses existing evidence field, gives an overview different fortification approaches definitions, outlines gaps knowledge recommendations practice suggestions future research. EMBA recognizes "Standard Fortification," which currently most utilized regimen neonatal intensive care units, still falls supplying protein some VLBW infants. encourages use "Individualized Fortification" optimize nutrient intake. "Adjustable "Targeted are 2 methods individualized fortification. The quality source fortifiers constitute another important topic. There work looking derived fortifiers, it too early draw precise conclusions about their use. pros cons discussed Commentary addition around post discharge.

Language: Английский

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Compositional Dynamics of the Milk Fat Globule and Its Role in Infant Development

Frontiers in Pediatrics, Journal Year: 2018, Volume and Issue: 6

Published: Oct. 24, 2018

Human milk is uniquely optimized for the needs of developing infant. Its composition complex and dynamic, driven primarily by maternal genetics, to a lesser extent diet environment. One important component that gaining attention fat globule (MFG). The MFG composed triglyceride-rich core surrounded tri-layer membrane, also known as membrane (MFGM) originates from mammary gland epithelia. MFGM enriched with glycerophospholipids, sphingolipids, cholesterol, proteins, some which are glycosylated, exert numerous biological roles. Mounting evidence suggests structure bioactive components may benefit infant aiding in structural functional maturation gut through provision essential nutrients and/or regulating various cellular events during growth immune education. Further, antimicrobial peptides surface carbohydrate moieties surrounding might have pivotal role shaping microbial populations, turn promote protection against inflammatory diseases early life. This review seeks to: (1) understand MFG, well factors including genetic lifestyle influence its characteristics; (2) examine potential this on intestinal system; (3) delineate mechanistic roles establishment microbiota alimentary canal.

Language: Английский

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Human milk fat substitutes: Past achievements and current trends

Progress in Lipid Research, Journal Year: 2019, Volume and Issue: 74, P. 69 - 86

Published: Feb. 21, 2019

Language: Английский

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The Relationship Between Breast Milk Components and the Infant Gut Microbiota

Frontiers in Nutrition, Journal Year: 2021, Volume and Issue: 8

Published: March 22, 2021

The assembly of the newborn's gut microbiota during first months life is an orchestrated process resulting in specialized microbial ecosystems different compartments. This highly dependent upon environmental factors, and many evidences suggest that early bacterial colonization has long-term consequences on host digestive immune homeostasis but also metabolism behavior. period therefore a "window opportunity" to program health through modulation. However, implementation this promising strategy requires in-depth understanding mechanisms governing assembly. Breastfeeding been associated with healthy infants. Human milk complex food matrix, numerous components potentially influence infant composition, either by enhancing specific bacteria growth or limiting others. objective review describe human composition discuss established purported roles establishment. Finally, impact maternal diet reviewed assess how could be simple efficient approach shape microbiota.

Language: Английский

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S3 Guideline Allergy Prevention

Allergologie select, Journal Year: 2022, Volume and Issue: 6(01), P. 61 - 97

Published: Jan. 1, 2022

The persistently high prevalence of allergic diseases in Western industrial nations and the limited possibilities causal therapy make evidence-based recommendations for primary prevention necessary.

Language: Английский

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Macro- and Micronutrients of Human Milk Composition: Are They Related to Maternal Diet? A Comprehensive Systematic Review

Breastfeeding Medicine, Journal Year: 2017, Volume and Issue: 12(9), P. 517 - 527

Published: Sept. 7, 2017

This study aims at systematically reviewing the observational and interventional studies on association of maternal macro- micronutrient intake with breast milk content.We searched Medline via PubMed, Scopus, ISI Web Knowledge till October 2016 following search strategy: ("human milk" OR "breast composition" "human "composition "mother milk") AND ("maternal diet" "maternal nutrition"). We also Google scholar for increasing sensitivity our search. The was not limited to title abstract due possibility that desired outcome might have been considered a secondary aim. excluded conference papers, editorials, letters, commentary, short survey, notes. refined English language, we did consider any time limitation. To increase select more studies, reference list published checked as well.This review included 59 43 diet related composition. Different determined associations effects some dietary micro macronutrients its reflection in human milk.Maternal intake, particularly fatty acids, micronutrients, including fat soluble vitamins, vitamin B1, C, their content

Language: Английский

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Chemistry of Human Breast Milk—A Comprehensive Review of the Composition and Role of Milk Metabolites in Child Development

Journal of Agricultural and Food Chemistry, Journal Year: 2018, Volume and Issue: 66(45), P. 11881 - 11896

Published: Sept. 24, 2018

Early nutrition has an enormous influence on a child's physiological function, immune system maturation, and cognitive development. Human breast milk (HBM) is recognized as the gold standard for human infant nutrition. According to WHO report, breastfeeding considered unequaled way of providing ideal food infant, which required his healthy growth HBM contains various macronutrients (carbohydrates, proteins, lipids, vitamins) well numerous bioactive compounds interactive elements (growth factors, hormones, cytokines, chemokines, antimicrobial compounds. The aim this review summarize discuss current knowledge about metabolites, are least understood components HBM, their potential role in We focus small metabolites (<1500 Da) characterize chemical structure biological function polar such oligosaccharides, nonprotein molecules containing nitrogen (creatine, amino acids, nucleotides, polyamines), nonpolar lipids. believe that manuscript will provide comprehensive insight into metabolite composition, structure, early life

Language: Английский

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Lipids in human milk

Best Practice & Research Clinical Endocrinology & Metabolism, Journal Year: 2017, Volume and Issue: 32(1), P. 57 - 68

Published: Nov. 14, 2017

Language: Английский

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Human Milk Nutrient Composition in the United States: Current Knowledge, Challenges, and Research Needs

Current Developments in Nutrition, Journal Year: 2018, Volume and Issue: 2(7), P. nzy025 - nzy025

Published: May 30, 2018

Human milk is considered to be the ideal food for infants. Accurate, representative, and up-to-date nutrient composition data of human are crucial management infant feeding, assessment maternal nutritional needs, as a guide developing formula. Currently in United States, profiles can found USDA National Nutrient Database Standard Reference, books or review articles. Nonetheless, these resources all suffer major drawbacks, such being outdated, incomplete profiles, limited sources data, uncertain quality. Furthermore, no profile was developed specifically US population. The purposes this were summarize current knowledge from studies conducted States Canada, identify gaps research needs. literature cover years 1980-2017, 28 papers containing original on macronutrients micronutrients. Most published before 1990 mainly examined samples small groups generally healthy lactating women. experimental designs, including sampling, storage, analytic methods, varied substantially between different studies. Data several components showed some consistency 1-6 mo postpartum, especially protein, fat, lactose, energy, certain minerals (e.g., calcium). 7-12 postpartum other nutrients very scarce. Comprehensive required provide complete information States.

Language: Английский

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