Association of per- and polyfluoroalkyl substances with constipation: The National Health and Nutrition Examination Survey (2005–2010) DOI Creative Commons
Yifan Zhao, Ke Pu, Ya Zheng

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(4), P. e0301129 - e0301129

Published: April 1, 2024

Background The impact of per- and polyfluoroalkyl substances (PFAS) on constipation, as mediated through gastrointestinal absorption perturbations to the intestinal microecology, remains poorly understood. Objective This study seeks explain relationship between PFAS constipation. Methods A total 2945 adults from National Health Nutrition Examination Survey (NHANES) 2005–2010 were included in this study. Constipation was defined using Bristol Stool Form Scale (BSFS) based stool consistency. constipation evaluated weighted logistic regression restricted cubic spline (RCS) analysis, while adjusting for confounding variables. Results median concentration (ΣPFAS) significantly lower individuals with (19.01 μg/L) compared those without (23.30 (p < 0.0001). Subgroup analysis revealed that cumulative effect more pronounced elderly, men, obesity, high school education or equivalent, high-income 0.05). After factors, multivariable demonstrated an inverse association PFOA [OR (95% CI), 0.666(0.486,0.914)] PFHxS 0.699(0.482,1.015)], None personal lifestyle factors showed a significant correlation negative association, confirmed by subgroup interaction testing > RCS linear levels Conclusion findings provide evidence serum concentrations PFAS, particularly PFHxS,

Language: Английский

Global prevalence of constipation in older adults: a systematic review and meta-analysis DOI
Nader Salari, Mohammadrasool Ghasemianrad, Mojtaba Ammari‐Allahyari

et al.

Wiener klinische Wochenschrift, Journal Year: 2023, Volume and Issue: 135(15-16), P. 389 - 398

Published: Feb. 24, 2023

Language: Английский

Citations

36
The relationship between oxidative balance scores and chronic diarrhea and constipation: a population-based study DOI Creative Commons
Jiayan Hu, Hede Zou,

Xiyun Qiao

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: May 21, 2024

Abstract Background Oxidative stress is closely related to gut health. Exposures oxidative in one’s diet and lifestyle can be evaluated by the balance score (OBS). However, relationship between OBS intestinal habits unknown. This study aimed investigate relationships (chronic diarrhea chronic constipation) underlying mechanisms involved. Methods Using data from National Health Nutrition Examination Survey (NHANES) database 2005 2010, we included a total of 8065 participants. Twenty dietary factors were selected for calculates. Chronic constipation defined using Bristol stool form scale (BSFS) types 1 2 BSFS 6 7, respectively. Multivariate logistic regression, subgroup analysis, restricted cubic splines (RCS) analysis used evaluate defecation habits. Finally, mediation explore indirect effects inflammatory markers on these associations. Results After adjusting all covariates, multivariate regression revealed that was negatively correlated with (OR = 0.57; 95%CI 0.39–0.83; P 0.008)and positively 1.75; 1.19–2.25; 0.008). The RCS showed nonlinear ( nonlinearity 0.02) linear 0.19). Mediation C-reactive protein (CRP) concentration white blood cell (WBC) count mediated correlation 6.28% 6.53%, respectively < 0.05). Conclusions changes patients' inflammation may play role two. result emphasizes importance public their according own situation. further prospective studies are needed analyze

Language: Английский

Citations

13
Analysis of Factors Associated with Constipation in the Population with Obesity: Evidence from the National Health and Nutrition Examination Survey DOI Creative Commons

Y. Mark Hong,

Xing‐Xing Chen, Jun‐Ping Liu

et al.

Obesity Facts, Journal Year: 2024, Volume and Issue: 17(2), P. 169 - 182

Published: Jan. 1, 2024

Obesity and constipation are both global problems, but the factors associated with in individuals obesity currently understudied. The aim of our study was to explore people obesity.

Language: Английский

Citations

7
Association between dietary vitamin E intake and constipation: NHANES 2005–2010 DOI Creative Commons

Junfeng Cai,

Danqing Li,

Rui-Jun Xie

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Aug. 20, 2024

This investigation aimed to analyze the association between dietary vitamin E intake and constipation prevalence among United States adults.

Language: Английский

Citations

6
Anti-obesogenic effects of plant natural products: A focus on Korean traditional foods DOI
Gitishree Das, Luis Alfonso Jiménez‐Ortega, Sandra Gonçalves

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 148, P. 104470 - 104470

Published: March 29, 2024

Language: Английский

Citations

6
Prevalence of chronic diarrhea and its association with obesity in a Chinese community-based population DOI Creative Commons
Ke Han,

Xiangyao Wang,

Yan Wang

et al.

Chinese Medical Journal, Journal Year: 2024, Volume and Issue: unknown

Published: June 24, 2024

Abstract Background: Epidemiological data on chronic diarrhea in the Chinese population are lacking, and association between obesity East Asian populations remains inconclusive. This study aimed to investigate prevalence of its with a representative community-dwelling population. Methods: cross-sectional was based multistage, randomized cluster sampling involving 3503 residents aged 20–69 years from urban rural communities Beijing. Chronic assessed using Bristol Stool Form Scale (BSFS), determined body mass index (BMI). Logistic regression analysis restricted cubic splines were used evaluate relationship diarrhea. Results: The standardized 12.88%. average BMI 24.67 kg/m 2 . Of all participants, 35.17% (1232/3503) participants classified as overweight 16.13% (565/3503) obese. After adjustment for potential confounders, individuals had an increased risk compared normal weight (odds ratio = 1.58, 95% confidence interval: 1.20–2.06). A nonlinear observed community males overall participant group ( P 0.026 0.017, respectively). Conclusions: presents initial findings among while offering substantiated evidence regarding significant These offer novel perspective gastrointestinal health management.

Language: Английский

Citations

5
Association between weight-adjusted-waist index and bowel habits DOI Creative Commons

Xiaoxian Yang,

Zhiguang Sun

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: July 26, 2024

Obesity has become a global public health issue and is closely related to bowel habits. The Weight-Adjusted-Waist Index (WWI), new indicator of obesity, provides more accurate assessment central obesity. This study aims investigate the relationship between WWI 2005–2010 National Health Nutrition Examination Survey (NHANES) dataset was used for cross-sectional survey. Bowel habits were defined by self-report. Multiple logistic regression models test linear association with chronic diarrhea constipation. Fitted smoothed curves threshold effects analysis characterize nonlinear relationships. Subgroup analyses interaction tests determine heterogeneity stability study. population-based included 14,238 adults (≥ 20 years). After adjusting covariates, there significant positive (OR [95% CI] 1.27 [1.14, 1.41]). There non-linear constipation, we found breakpoint 9.77, correlation on left side no statistical significance right side. showed stable consistent results across stratification factors. Elevated levels are associated an increased risk diarrhea. A range < 9.77 valid assessing intestinal in U.S. adults, should be mindful importance maintaining good body fat our daily lives maintain healthy

Language: Английский

Citations

5
Association between visceral adiposity index and bowel habits and inflammatory bowel disease: a cross-sectional study DOI Creative Commons

Xiaoxian Yang,

Manli Wang,

Ren Lang

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 13, 2024

Obesity has become a global public health problem, and its relationship with gastrointestinal diseases major concern. The visceral adiposity index (VAI) is novel to assess the distribution content of fat, this study aimed investigate association between VAI bowel habits (chronic diarrhea, chronic constipation) inflammatory disease (IBD). 2005–2010 National Health Nutrition Examination Survey (NHANES) dataset was used for cross-sectional survey. Bowel IBD were defined by self-report. Multiple logistic regression models test linear IBD. Fitted smoothed curves threshold effects analyses characterize nonlinear relationships. This included 10,391 adults (≥ 20 years). After adjusting covariates, there significant negative constipation (OR [95% CI]: 0.97 [0.95, 1.00]) but no [0.87, 1.07]). Additionally, diarrhea breakpoint 3.08, positive correlation two on left side statistical significance right side. Subgroup interaction tests showed that maintaining sleep associated low risk constipation. Elevated levels negatively constipation, elevated positively at < 3.08. reminds us moderate fat may prevent onset circumvent diarrhea. Notably, healthy play role in reducing

Language: Английский

Citations

5
Association of the body roundness index with chronic diarrhea and chronic constipation: findings based on the National Health and Nutrition Examination Survey 2005–2010 data DOI Creative Commons
Yinda Wang, Fei Chen, Binzhong Zhang

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 31, 2025

The study aimed to explore potential links between long-term digestive issues (specifically diarrhea and constipation) body roundness index (BRI) in a representative U.S. population sample. This adopted design that is cross sectional, drawing on data from the NHANES, gathered 2005 2010 with health information total of 11,235 individuals. Persistent bowel movement patterns were categorized based BSFS-Bristol Stool Form Scale, while stool types 1 2 designated as indicators constipation 6 7 identified markers persistent diarrhea. To assess relationship BRI, this employed weighted logistic regression analysis. capture visualize nuanced interplay BRI gastrointestinal patterns, we utilized advanced nonlinear methods, specifically restricted cubic spline (RCS) analyses. Additionally, research compared efficacy various physical measurements-including WC, BMI (body index, waist circumference, mass respectively)-to determine their respective diagnostic power for chronic through comparative analysis receiver operating characteristic (ROC) curves. After comprehensive adjustment final statistical model (Model 3), demonstrated statistically significant associations constipation. RCS further uncovered positive (P = 0.005) 0.037). Further stratified analyses revealed was particularly evident among individuals diabetes. In contrast, association stronger under 60 years age. ROC indicated outperformed conventional anthropometric measures (AUC, area curve: 0.601). Specifically, resulted an AUC 0.569, WC produced 0.572. However, value (0.537) less effective than (0.551) (0.570) diagnosing strongly associated changes individual's habits, highlighted significance maintaining moderate levels improve prevent

Language: Английский

Citations

0
Fluid intake, fiber consumption, and physical activity related to constipation among elderly, which one is more important? A cross-sectional study in Iran DOI Creative Commons
Maryam Safarnavadeh, Leili Salehi, Zohreh Mahmoodi

et al.

The North African Journal of Food and Nutrition Research, Journal Year: 2025, Volume and Issue: 9(19), P. 30 - 40

Published: Feb. 2, 2025

Background: Chronic constipation is a common, self-reported, and symptom-based disorder which can significantly influence an individual’s health-related quality of life imposes several financial costs. Aims: The present study aimed to evaluate the effect water consumption, fiber intake, physical activity (PA) on constipation, one more critical by considering mediating BMI. Subjects Methods: This cross-sectional involved 400 older adults in 2019 referring comprehensive health service centers Karaj, capital Alborz province. data were collected using questionnaires demographic anthropometric characteristics, PASE (Physical for elderly), fluid FFQ (Food Frequency questionnaire), Wexner Persian lifestyle questionnaire analyzed SPSS LISREL software. Results: Based final fitted model, PA most constipation-related factor compared intake consumption. In addition, consumption second crucial affecting there negative association between intake. Conclusion: As price barriers among elderly, recommendation do such as walking solve efficient inexpensive individuals with different socio-economic status. Keywords: Physical activity, Iran.

Language: Английский

Citations

0