Interpreting magnesium status to enhance clinical care DOI
Rebecca B. Costello, Forrest H. Nielsen

Current Opinion in Clinical Nutrition & Metabolic Care, Journal Year: 2017, Volume and Issue: 20(6), P. 504 - 511

Published: Aug. 14, 2017

To update advances in identifying factors affecting magnesium (Mg) status that assist providing improved evidence-based clinical decision-making for assessing Mg status.Findings from recent cohort studies, small randomized control trials, and multiple meta-analyses reinforce earlier work serum concentrations, urinary excretion, dietary intakes are inversely associated with cardiovascular disease, chronic kidney diabetes. These studies indicate the reference range needs updating, individuals of 0.75-0.85 mmol/l displaying changes other a low may be deficient. Individuals concentrations below this most likely deficient and, above range, sufficient.The combined determination concentration, 24-h intake is currently practical method to obtain sound assessment status. The strong correlations deficiency increased risk several diseases, some which exist as comorbidities, should ascertained patients presenting such disorder.

Language: Английский

The Role of Diet in the Prevention of Hypertension and Management of Blood Pressure: An Umbrella Review of Meta-Analyses of Interventional and Observational Studies DOI Creative Commons
Ghadeer S. Aljuraiban, Rachel Gibson, Doris S. M. Chan

et al.

Advances in Nutrition, Journal Year: 2023, Volume and Issue: 15(1), P. 100123 - 100123

Published: Oct. 1, 2023

High blood pressure (BP), is a major pathological risk factor for the development of several cardiovascular diseases. Diet key modifier BP, but underlying relationships are not clearly demonstrated. This an umbrella review published meta-analyses to critically evaluate wide-range dietary evidence from bioactive compounds patterns on BP and hypertension. PubMed, Embase, Web Science, Cochrane Central Register Controlled Trials were searched inception until 31st October 2021 relevant randomized controlled trials or observational studies. A total 175 publications reporting 341 (145 publications) 70 studies (30 included in review. The methodological quality was assessed using Assessment Multiple Systematic Reviews 2 (AMSTAR 2) each selected meta-analysis NutriGrade. supports recommended public health guidelines prevention control Dietary including Approaches Stop Hypertension (DASH) Mediterraneantype diets that further restrict sodium, moderate alcohol intake advised. To produce high substantiate strong recommendations, future research should address areas where low observed (e.g. fiber, fish, egg, meat, dairy products, fruit juice, nuts) emphasize focus factors yet conclusively investigated.

Language: Английский

Citations

26

Higher Magnesium Depletion Score Increases the Risk of All-cause and Cardiovascular Mortality in Hypertension Participants DOI
Jingjing Song, Yujun Zhang,

ZhiGen Lin

et al.

Biological Trace Element Research, Journal Year: 2024, Volume and Issue: unknown

Published: June 4, 2024

Language: Английский

Citations

13

Dietary Approaches to Stop Hypertension (DASH): potential mechanisms of action against risk factors of the metabolic syndrome DOI
Masoumeh Akhlaghi

Nutrition Research Reviews, Journal Year: 2019, Volume and Issue: 33(1), P. 1 - 18

Published: July 30, 2019

Abstract The metabolic syndrome is a cluster of disorders dominated by abdominal obesity, hypertriacylglycerolaemia, low HDL-cholesterol, high blood pressure and fasting glucose. Diet modification safe effective way to treat the syndrome. Dietary Approaches Stop Hypertension (DASH) dietary pattern rich in fruits, vegetables low-fat dairy products, meats sweets. DASH provides good amounts fibre, K, Ca Mg, limited quantities total fat, saturated cholesterol Na. Although was initially designed for prevention or control hypertension, using diet has other benefits. In present review, effect each component on risk factors discussed. Due fat fibre content, individuals are less prone overweight obesity possess lower concentrations LDL-cholesterol although changes TAG HDL-cholesterol have been significant available evidence this regard still inconclusive. Moreover, fruit provide great Mg all which shown reduce pressure. antioxidants also correcting glucose insulin abnormalities. Evidence provided from cross-sectional investigations, cohort studies randomised controlled trials, and, where available, published meta-analyses. Mechanisms described according human case lack evidence, animal cell culture investigations.

Language: Английский

Citations

76

Magnesium and health outcomes: an umbrella review of systematic reviews and meta-analyses of observational and intervention studies DOI
Nicola Veronese, Jacopo Demurtas, Gabriella Pesolillo

et al.

European Journal of Nutrition, Journal Year: 2019, Volume and Issue: 59(1), P. 263 - 272

Published: Jan. 25, 2019

Language: Английский

Citations

75

The Association of Serum and Dietary Magnesium with Depressive Symptoms DOI Open Access

Ming-Hui Chou,

Yen Kuang Yang, Jung‐Der Wang

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(3), P. 774 - 774

Published: Feb. 2, 2023

Depression is a leading cause of the global burden disease and has multifactorial etiology that includes nutrients. Magnesium status been associated with depression inconclusive results. The impact chronic latent magnesium deficiency (CLMD, 0.75 ≤ serum < 0.85 mmol/L) on not yet investigated. We assessed association between levels/dietary intake depressive symptoms by analyzing nationally representative data from Taiwan (Nutrition Health Survey in Taiwan, NAHSIT). used 5-item Brief Symptom Rating Scale to measure symptoms. Subgroup analysis sex was also performed. Serum levels had low correlation dietary intake. Higher were lower scores risk symptoms, but showed no association. Sex differences found. Compared subjects <0.75 mmol/L, those ≥0.85 mmol/L scores. In conclusion, inversely not. Subjects CLMD similar at mmol/L. should be considered while assessing

Language: Английский

Citations

17

Magnesium and Blood Pressure: A Physiology-Based Approach DOI
Joëlle C. Schutten, Michel M. Joosten, Martin H. de Borst

et al.

Advances in Chronic Kidney Disease, Journal Year: 2018, Volume and Issue: 25(3), P. 244 - 250

Published: May 1, 2018

Language: Английский

Citations

55

Dietary Magnesium and Chronic Disease DOI
Forrest H. Nielsen

Advances in Chronic Kidney Disease, Journal Year: 2018, Volume and Issue: 25(3), P. 230 - 235

Published: May 1, 2018

Language: Английский

Citations

53

The Effect of Electrolytes on Blood Pressure: A Brief Summary of Meta-Analyses DOI Open Access
Sehar Iqbal,

N Klammer,

Cem Ekmekçioğlu

et al.

Nutrients, Journal Year: 2019, Volume and Issue: 11(6), P. 1362 - 1362

Published: June 17, 2019

Nutrition is known to exert an undeniable impact on blood pressure with especially salt (sodium chloride), but also potassium, playing a prominent role. The aim of this review was summarize meta-analyses studying the effect different electrolytes or risk for hypertension, respectively. Overall, 32 evaluating sodium, calcium and magnesium human hypertension were included after literature search. Most showed beneficial lowering effects extent systolic reduction ranging between -0.7 (95% confidence interval: -2.6 1.2) -8.9 (-14.1 -3.7) mmHg sodium/salt reduction, -3.5 (-5.2 -1.8) -9.5 (-10.8 -8.1) -0.2 (-0.4 -0.03) -18.7 (-22.5 -15.0) magnesium. range diastolic 0.03 0.4) -5.9 (-9.7 -2.1) -2 (-3.1 -0.9) -6.4 (-7.3 -5.6) -0.3 (-0.5 -10.9 (-13.1 -8.7) Moreover, sufficient intake found reduce gestational hypertension.

Language: Английский

Citations

49

Hypomagnesemia and Cardiovascular Risk in Type 2 Diabetes DOI Creative Commons
Lynette J. Oost, Cees J. Tack, Jeroen H. F. de Baaij

et al.

Endocrine Reviews, Journal Year: 2022, Volume and Issue: 44(3), P. 357 - 378

Published: Nov. 8, 2022

Abstract Hypomagnesemia is 10-fold more common in individuals with type 2 diabetes (T2D) than the healthy population. Factors that are involved this high prevalence low Mg2+ intake, gut microbiome composition, medication use, and presumably genetics. associated insulin resistance, which subsequently increases risk to develop T2D or deteriorates glycemic control existing diabetes. supplementation decreases T2D-associated features like dyslipidemia inflammation, important factors for cardiovascular disease (CVD). Epidemiological studies have shown an inverse association between serum of developing heart failure (HF), atrial fibrillation (AF), microvascular T2D. The potential protective effect on HF AF may be explained by reduced oxidative stress, fibrosis, electrical remodeling heart. In disease, reduces detrimental effects hyperglycemia improves endothelial dysfunction; however, clinical assessing long-term CVD incidents lacking, gaps remain how reduce Despite hypomagnesemia people T2D, routine screening deficiency provide when needed not implemented care as sufficient evidence lacking. conclusion, both cause, probably through molecular mechanisms leading consequence prospectively development HF, AF, complications. Whether beneficial, remains determined.

Language: Английский

Citations

28

Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia DOI

Mengying Han,

Yixin Zhang, Jiaxin Fang

et al.

Hypertension Research, Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 11, 2023

Language: Английский

Citations

15