Current Opinion in Clinical Nutrition & Metabolic Care,
Journal Year:
2017,
Volume and Issue:
20(6), P. 504 - 511
Published: Aug. 14, 2017
To
update
advances
in
identifying
factors
affecting
magnesium
(Mg)
status
that
assist
providing
improved
evidence-based
clinical
decision-making
for
assessing
Mg
status.Findings
from
recent
cohort
studies,
small
randomized
control
trials,
and
multiple
meta-analyses
reinforce
earlier
work
serum
concentrations,
urinary
excretion,
dietary
intakes
are
inversely
associated
with
cardiovascular
disease,
chronic
kidney
diabetes.
These
studies
indicate
the
reference
range
needs
updating,
individuals
of
0.75-0.85
mmol/l
displaying
changes
other
a
low
may
be
deficient.
Individuals
concentrations
below
this
most
likely
deficient
and,
above
range,
sufficient.The
combined
determination
concentration,
24-h
intake
is
currently
practical
method
to
obtain
sound
assessment
status.
The
strong
correlations
deficiency
increased
risk
several
diseases,
some
which
exist
as
comorbidities,
should
ascertained
patients
presenting
such
disorder.
Advances in Nutrition,
Journal Year:
2023,
Volume and Issue:
15(1), P. 100123 - 100123
Published: Oct. 1, 2023
High
blood
pressure
(BP),
is
a
major
pathological
risk
factor
for
the
development
of
several
cardiovascular
diseases.
Diet
key
modifier
BP,
but
underlying
relationships
are
not
clearly
demonstrated.
This
an
umbrella
review
published
meta-analyses
to
critically
evaluate
wide-range
dietary
evidence
from
bioactive
compounds
patterns
on
BP
and
hypertension.
PubMed,
Embase,
Web
Science,
Cochrane
Central
Register
Controlled
Trials
were
searched
inception
until
31st
October
2021
relevant
randomized
controlled
trials
or
observational
studies.
A
total
175
publications
reporting
341
(145
publications)
70
studies
(30
included
in
review.
The
methodological
quality
was
assessed
using
Assessment
Multiple
Systematic
Reviews
2
(AMSTAR
2)
each
selected
meta-analysis
NutriGrade.
supports
recommended
public
health
guidelines
prevention
control
Dietary
including
Approaches
Stop
Hypertension
(DASH)
Mediterraneantype
diets
that
further
restrict
sodium,
moderate
alcohol
intake
advised.
To
produce
high
substantiate
strong
recommendations,
future
research
should
address
areas
where
low
observed
(e.g.
fiber,
fish,
egg,
meat,
dairy
products,
fruit
juice,
nuts)
emphasize
focus
factors
yet
conclusively
investigated.
Nutrition Research Reviews,
Journal Year:
2019,
Volume and Issue:
33(1), P. 1 - 18
Published: July 30, 2019
Abstract
The
metabolic
syndrome
is
a
cluster
of
disorders
dominated
by
abdominal
obesity,
hypertriacylglycerolaemia,
low
HDL-cholesterol,
high
blood
pressure
and
fasting
glucose.
Diet
modification
safe
effective
way
to
treat
the
syndrome.
Dietary
Approaches
Stop
Hypertension
(DASH)
dietary
pattern
rich
in
fruits,
vegetables
low-fat
dairy
products,
meats
sweets.
DASH
provides
good
amounts
fibre,
K,
Ca
Mg,
limited
quantities
total
fat,
saturated
cholesterol
Na.
Although
was
initially
designed
for
prevention
or
control
hypertension,
using
diet
has
other
benefits.
In
present
review,
effect
each
component
on
risk
factors
discussed.
Due
fat
fibre
content,
individuals
are
less
prone
overweight
obesity
possess
lower
concentrations
LDL-cholesterol
although
changes
TAG
HDL-cholesterol
have
been
significant
available
evidence
this
regard
still
inconclusive.
Moreover,
fruit
provide
great
Mg
all
which
shown
reduce
pressure.
antioxidants
also
correcting
glucose
insulin
abnormalities.
Evidence
provided
from
cross-sectional
investigations,
cohort
studies
randomised
controlled
trials,
and,
where
available,
published
meta-analyses.
Mechanisms
described
according
human
case
lack
evidence,
animal
cell
culture
investigations.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(3), P. 774 - 774
Published: Feb. 2, 2023
Depression
is
a
leading
cause
of
the
global
burden
disease
and
has
multifactorial
etiology
that
includes
nutrients.
Magnesium
status
been
associated
with
depression
inconclusive
results.
The
impact
chronic
latent
magnesium
deficiency
(CLMD,
0.75
≤
serum
<
0.85
mmol/L)
on
not
yet
investigated.
We
assessed
association
between
levels/dietary
intake
depressive
symptoms
by
analyzing
nationally
representative
data
from
Taiwan
(Nutrition
Health
Survey
in
Taiwan,
NAHSIT).
used
5-item
Brief
Symptom
Rating
Scale
to
measure
symptoms.
Subgroup
analysis
sex
was
also
performed.
Serum
levels
had
low
correlation
dietary
intake.
Higher
were
lower
scores
risk
symptoms,
but
showed
no
association.
Sex
differences
found.
Compared
subjects
<0.75
mmol/L,
those
≥0.85
mmol/L
scores.
In
conclusion,
inversely
not.
Subjects
CLMD
similar
at
mmol/L.
should
be
considered
while
assessing
Nutrients,
Journal Year:
2019,
Volume and Issue:
11(6), P. 1362 - 1362
Published: June 17, 2019
Nutrition
is
known
to
exert
an
undeniable
impact
on
blood
pressure
with
especially
salt
(sodium
chloride),
but
also
potassium,
playing
a
prominent
role.
The
aim
of
this
review
was
summarize
meta-analyses
studying
the
effect
different
electrolytes
or
risk
for
hypertension,
respectively.
Overall,
32
evaluating
sodium,
calcium
and
magnesium
human
hypertension
were
included
after
literature
search.
Most
showed
beneficial
lowering
effects
extent
systolic
reduction
ranging
between
-0.7
(95%
confidence
interval:
-2.6
1.2)
-8.9
(-14.1
-3.7)
mmHg
sodium/salt
reduction,
-3.5
(-5.2
-1.8)
-9.5
(-10.8
-8.1)
-0.2
(-0.4
-0.03)
-18.7
(-22.5
-15.0)
magnesium.
range
diastolic
0.03
0.4)
-5.9
(-9.7
-2.1)
-2
(-3.1
-0.9)
-6.4
(-7.3
-5.6)
-0.3
(-0.5
-10.9
(-13.1
-8.7)
Moreover,
sufficient
intake
found
reduce
gestational
hypertension.
Endocrine Reviews,
Journal Year:
2022,
Volume and Issue:
44(3), P. 357 - 378
Published: Nov. 8, 2022
Abstract
Hypomagnesemia
is
10-fold
more
common
in
individuals
with
type
2
diabetes
(T2D)
than
the
healthy
population.
Factors
that
are
involved
this
high
prevalence
low
Mg2+
intake,
gut
microbiome
composition,
medication
use,
and
presumably
genetics.
associated
insulin
resistance,
which
subsequently
increases
risk
to
develop
T2D
or
deteriorates
glycemic
control
existing
diabetes.
supplementation
decreases
T2D-associated
features
like
dyslipidemia
inflammation,
important
factors
for
cardiovascular
disease
(CVD).
Epidemiological
studies
have
shown
an
inverse
association
between
serum
of
developing
heart
failure
(HF),
atrial
fibrillation
(AF),
microvascular
T2D.
The
potential
protective
effect
on
HF
AF
may
be
explained
by
reduced
oxidative
stress,
fibrosis,
electrical
remodeling
heart.
In
disease,
reduces
detrimental
effects
hyperglycemia
improves
endothelial
dysfunction;
however,
clinical
assessing
long-term
CVD
incidents
lacking,
gaps
remain
how
reduce
Despite
hypomagnesemia
people
T2D,
routine
screening
deficiency
provide
when
needed
not
implemented
care
as
sufficient
evidence
lacking.
conclusion,
both
cause,
probably
through
molecular
mechanisms
leading
consequence
prospectively
development
HF,
AF,
complications.
Whether
beneficial,
remains
determined.