Green synthesis of nanoparticles: Current developments and limitations

Environmental Technology & Innovation, Journal Year: 2022, Volume and Issue: 26, P. 102336 - 102336

Published: Jan. 17, 2022

Nanoscale metals are widely used in many fields such as environment, medicine, and engineering that synthesis of nanoscale is a timely topic. At present, mainly synthesized by chemical methods have unintended effects environmental pollution, large energy consumption, potential health problems. In response to these challenges, green synthesis, which uses plant extracts instead industrial agents reduce metal ions, has been developed. Green more beneficial than traditional because it costs less, decreases improves human safety. this review, current developments the nanoparticles gold (Au NPs), silver (Ag palladium (Pd copper (Cu iron its oxide (Fe NPs) were evaluated. Major findings reveal complexity geographical seasonal distributions plants their compositions limited time place production well issues with low purity poor yield. However, considering problems pollution associated offers alternative development prospects applications.

Language: Английский

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Electrochemical Sensors and Their Applications: A Review

Chemosensors, Journal Year: 2022, Volume and Issue: 10(9), P. 363 - 363

Published: Sept. 9, 2022

The world of sensors is diverse and advancing at a rapid pace due to the fact its high demand constant technological improvements. Electrochemical provide low-cost convenient solution for detection variable analytes are widely utilized in agriculture, food, oil industries as well environmental biomedical applications. popularity electrochemical sensing stems from two main advantages: variability reporting signals, such voltage, current, overall power output, or impedance, low theoretical limits that originate differences Faradaic nonFaradaic currents. This review article attempts cover latest advances applications different industries. role nanomaterials sensor research advancements also examined. We believe information presented here will encourage further efforts on understanding progress sensors.

Language: Английский

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RETRACTED: Green Synthesis of Metallic Nanoparticles and Their Potential Applications to Treat Cancer

Frontiers in Chemistry, Journal Year: 2020, Volume and Issue: 8

Published: Oct. 29, 2020

Nanoparticle synthesis using microorganisms and plants by green technology is biologically safe, cost-effective, environment-friendly. Plants have established the power to devour accumulate inorganic metal ions from their neighboring niche. The biological entities are known synthesize nanoparticles both extra intracellularly. capability of a living system utilize its intrinsic organic chemistry processes in remodeling into has opened up an undiscovered area biochemical analysis. Nanotechnology conjunction with biology gives rise advanced nanobiotechnology that involves prokaryotic eukaryotic origin, such as algae, cyanobacteria, actinomycetes, bacteria, viruses, yeasts, fungi, plants. Every varies capabilities supply metallic nanoparticles. However, not all organisms can produce due enzymatic activities metabolic processes. Therefore, or extracts used for through bio-reduction particles leading These biosynthesized range unlimited pharmaceutical applications including delivery drugs genes, detection pathogens proteins, tissue engineering. effective engineering use nanotechnology exhibited vital contributions translational research related products applications. Collectively, this review covers various systems well

Language: Английский

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<p>A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle</p>

International Journal of Nanomedicine, Journal Year: 2020, Volume and Issue: Volume 15, P. 9823 - 9857

Published: Dec. 1, 2020

Abstract: Metal nanoparticles are being extensively used in biomedical fields due to their small size-to-volume ratio and extensive thermal stability. Gold (AuNPs) an obvious choice for applications amenability of synthesis, stabilization, functionalization, low toxicity, ease detection. In the past few decades, various chemical methods have been synthesis AuNPs, but recently, newer environment friendly green approaches AuNPs gained attention. can be conjugated with a number functionalizing moieties including ligands, therapeutic agents, DNA, amino acids, proteins, peptides, oligonucleotides. Recently, studies shown that gold not only infiltrate blood vessels reach site tumor also enter inside organelles, suggesting they employed as effective drug carriers. Moreover, after reaching target site, release payload upon external or internal stimulus. This review focuses on recent advances AuNPs. addition, strategies functionalization mechanisms application bio-macromolecule delivery payloads at comprehensively discussed. Keywords: nanoparticles, delivery, biological

Language: Английский

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Nano-Fertilization as an Emerging Fertilization Technique: Why Can Modern Agriculture Benefit from Its Use?

Plants, Journal Year: 2020, Volume and Issue: 10(1), P. 2 - 2

Published: Dec. 22, 2020

There is a need for more innovative fertilizer approach that can increase the productivity of agricultural systems and be environmentally friendly than synthetic fertilizers. In this article, we reviewed recent development potential benefits derived from use nanofertilizers (NFs) in modern agriculture. NFs have to promote sustainable agriculture overall crop productivity, mainly by increasing nutrient efficiency (NUE) field greenhouse crops. release their nutrients at slow steady pace, either when applied alone or combination with organic They 40-50 days, while fertilizers do same 4-10 days. Moreover, tolerance plants against biotic abiotic stresses. Here, advantages over fertilizers, as well different types macro micro NFs, are discussed detail. Furthermore, application smart role mitigation stress on presented. Though NF applications may many agriculture, there some concerns related nanoparticles (NPs) into environment, subsequent detrimental effects could both human animal health. Future research should explore green synthesized biosynthesized safe use, bioavailability, toxicity concerns.

Language: Английский

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Green approaches for the synthesis of metal and metal oxide nanoparticles using microbial and plant extracts

Nanoscale, Journal Year: 2022, Volume and Issue: 14(7), P. 2534 - 2571

Published: Jan. 1, 2022

Green synthesis approaches are gaining significance as promising routes for the sustainable preparation of nanoparticles, offering reduced toxicity towards living organisms and environment. Nanomaterials produced by green can offer additional benefits, including energy inputs lower production costs than traditional synthesis, which bodes well commercial-scale production. The biomolecules phytochemicals extracted from microbes plants, respectively, active compounds that function reducing stabilizing agents nanoparticles. Microorganisms, such bacteria, yeasts, fungi, algae, have been used in nanomaterials' biological some time. Furthermore, use plants or plant extracts metal metal-based hybrid nanoparticle represents a novel approach has attracted significant research interest. This review discusses various biosynthesis via oxide nanoparticles provides insights into molecular aspects mechanisms biomedical applications. agriculture waste potential bioresource applications biosynthesized is also discussed.

Language: Английский

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Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications

Molecules, Journal Year: 2021, Volume and Issue: 26(4), P. 844 - 844

Published: Feb. 5, 2021

The nanomaterial industry generates gigantic quantities of metal-based nanomaterials for various technological and biomedical applications; however, concomitantly, it places a massive burden on the environment by utilizing toxic chemicals production process leaving hazardous waste materials behind. Moreover, employed, often unpleasant can affect biocompatibility generated particles severely restrict their application possibilities. On these grounds, green synthetic approaches have emerged, offering eco-friendly, sustainable, nature-derived alternative methods, thus attenuating ecological footprint industry. In last decade, plethora biological has been tested to probe suitability synthesis. Although most were successful, large body evidence indicates that material or entity used would substantially define physical chemical properties as consequence, activities obtained nanomaterials. present review provides comprehensive collection recent methodologies, surveys major nanoparticle characterization techniques screens effects triggered in living systems give an impression potential synthesized silver gold nanoparticles.

Language: Английский

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Hesperidin Loaded on Gold Nanoparticles as a Drug Delivery System for a Successful Biocompatible, Anti-Cancer, Anti-Inflammatory and Phagocytosis Inducer Model

Scientific Reports, Journal Year: 2020, Volume and Issue: 10(1)

Published: June 9, 2020

Abstract Hesperidin is a flavonoid glycoside with proven therapeutic activities for various diseases, including cancer. However, its poor solubility and bioavailability render it only slightly absorbed, requiring delivery system to reach target. loaded on gold nanoparticles (Hsp-AuNPs) was prepared by chemical synthesis method. Various characterization techniques such as UV-VIS spectroscopy, FTIR, XRD, FESEM, TEM EDX, Zeta potential analysis, particle size were used confirm the of Hsp-AuNPs. The cytotoxic effect Hsp-AuNPs human breast cancer cell line (MDA-MB-231) assessed using MTT crystal violet assays. results revealed significant decrease in proliferation inhibition growth treated cells when compared normal epithelial (HBL-100). Determination apoptosis fluorescence microscope also performed acridine orange-propidium iodide dual staining assay. vivo study designed evaluate toxicity mice. levels hepatic kidney functionality markers assessed. No statistical differences found tested indicators. Histological images liver, spleen, lung showed no apparent damages histopathological abnormalities after treatment ameliorated functional activity macrophages against Ehrlich ascites tumor cells-bearing production pro-inflammatory cytokines bone marrow–derived macrophage obviously demonstrated that significantly inhibited secretion IL-1β, IL-6 TNF.

Language: Английский

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Biocompatibility and Cytotoxicity of Gold Nanoparticles: Recent Advances in Methodologies and Regulations

International Journal of Molecular Sciences, Journal Year: 2021, Volume and Issue: 22(20), P. 10952 - 10952

Published: Oct. 11, 2021

Recent advances in the synthesis of metal nanoparticles (MeNPs), and more specifically gold (AuNPs), have led to tremendous expansion their potential applications different fields, ranging from healthcare research microelectronics food packaging. The properties functionalised MeNPs can be fine-tuned depending on final application, subsequently, these strongly modulate biological effects. In this review, we will firstly focus impact MeNP characteristics (particularly nanoparticles, AuNPs) such as shape, size, aggregation activities. Moreover, detail vitro vivo assays performed when cytotoxicity biocompatibility must assessed. Due complex nature nanomaterials, conflicting studies views safety, it is clear that definition a standard biosafety label for AuNPs difficult. fact, AuNPs' affected by nanoparticles' intrinsic characteristics, target, methodology employed evaluate toxicity. last part current legislation requirements established regulatory authorities, defining main guidelines standards characterise new also discussed, aspect has not been reviewed recently. It lack well-established safety regulations based reliable, robust, universal methodologies hampered development field. Henceforth, international community make an effort adopt specific protocols characterisation products.

Language: Английский

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Green Synthesis of Gold Nanoparticles Using Plant Extracts as Beneficial Prospect for Cancer Theranostics

Molecules, Journal Year: 2021, Volume and Issue: 26(21), P. 6389 - 6389

Published: Oct. 22, 2021

Gold nanoparticles (AuNPs) have been widely explored and are well-known for their medical applications. Chemical physical synthesis methods a way to make AuNPs. In any case, the hunt other more ecologically friendly cost-effective large-scale technologies, such as environmentally biological processes known green synthesis, has gaining interest by worldwide researchers. The international focus on nanotechnology research resulted in various nanomaterials being used physiologically acceptable Several advantages over conventional chemical (simple, one-step approach synthesize, cost-effectiveness, energy efficiency, biocompatibility) drawn scientists’ attention exploring of AuNPs exploiting plants’ secondary metabolites. Biogenic approaches, mainly plant-based metal nanoparticles, chosen ideal strategy due environmental vivo safety, well ease synthesis. this review, we reviewed use synthesized treatment cancer utilizing phytochemicals found plant extracts. This article reviews producing AuNPs, characterization discusses physiochemical properties. study also recent breakthroughs achievements using different mechanisms action, reactive oxygen species (ROS), mediated mitochondrial dysfunction caspase activation, leading apoptosis, etc., anticancer cytotoxic effects. Understanding underlying therapeutic efficacy will aid developing personalized medicines treatments potential strategy.

Language: Английский

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