Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: March 13, 2023
The
rapid
healing
and
repair
of
skin
wounds
has
been
receiving
much
clinical
attention.
Covering
the
wound
with
dressing
to
promote
is
currently
main
treatment
for
repair.
However,
performance
prepared
by
a
single
material
limited
cannot
meet
requirements
complex
conditions
healing.
MXene
new
two-dimensional
electrical
conductivity,
antibacterial
photothermal
properties
other
physical
biological
properties,
which
wide
range
applications
in
field
biomedicine.
Based
on
pathophysiological
process
ideal
dressing,
this
review
will
introduce
preparation
modification
methods
MXene,
systematically
summarize
application
status
mechanism
healing,
provide
guidance
subsequent
researchers
further
apply
design
dressing.
Materials,
Journal Year:
2023,
Volume and Issue:
16(17), P. 6021 - 6021
Published: Sept. 1, 2023
Electrospun
nanofiber
membranes
(NFMs)
have
high
porosity
and
a
large
specific
surface
area,
which
provide
suitable
environment
for
the
complex
dynamic
wound
healing
process
number
of
sites
carrying
factors.
Further,
design
structure
can
imitate
human
dermis,
similar
to
natural
extracellular
matrix,
better
promotes
hemostasis,
anti-inflammatory
wounds.
Therefore,
it
has
been
widely
studied
in
field
dressing.
This
review
article
overviews
development
electrospinning
technology
application
electrospun
nanofibers
dressings.
It
begins
with
an
introduction
history,
working
principles,
transformation
electrospinning,
focus
on
selection
materials,
incorporation
functional
therapeutic
factors,
structural
membranes.
Moreover,
wide
NFMs
containing
factors
is
classified
based
their
special
functions,
such
as
antibacterial
cell
proliferation
promotion.
also
highlights
dressing,
including
porous
structures,
bead
core-shell
ordered
multilayer
membrane
structures.
Finally,
advantages
limitations
are
discussed,
challenges
faced
dressings
analyzed
promote
further
research
this
field.
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: May 6, 2023
Abstract
Nanobiotechnology,
as
a
novel
and
more
specialized
branch
of
science,
has
provided
number
nanostructures
such
nanoparticles,
by
utilizing
the
methods,
techniques,
protocols
other
branches
science.
Due
to
unique
features
physiobiological
characteristics,
these
or
nanocarriers
have
vast
methods
therapeutic
against
microbial
infections
cancers
for
tissue
regeneration,
engineering,
immunotherapies,
gene
therapies,
through
drug
delivery
systems.
However,
reduced
carrying
capacity,
abrupt
non-targeted
delivery,
solubility
agents,
can
affect
applications
biotechnological
products.
In
this
article,
we
explored
discussed
prominent
nanobiotechnological
products
nanocarriers,
highlighted
challenges
associated
with
products,
attempted
conclude
if
available
offer
any
scope
improvement
enhancement.
We
aimed
identify
emphasize
greater
prospect
capacity
improvements
enhancements.
found
that
nanostructures,
nanocomposites,
micelles,
hydrogels,
microneedles,
artificial
cells,
address
inherited
drawbacks,
help
conjugations,
sustained
stimuli-responsive
release,
ligand
binding,
targeted
delivery.
recommend
nanobiotechnology,
despite
having
few
offers
immense
opportunities
be
harnessed
in
delivering
quality
therapeutics
precision
prediction.
also
that,
exploring
branched
domains
rigorously,
bottlenecks
obstacles
addressed
resolved
return.
Graphical
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(3), P. 986 - 986
Published: March 19, 2023
Chronic
wounds
are
one
of
the
secondary
health
complications
that
develop
in
individuals
who
have
poorly
managed
diabetes
mellitus.
This
is
often
associated
with
delays
wound
healing
process,
resulting
from
long-term
uncontrolled
blood
glucose
levels.
As
such,
an
appropriate
therapeutic
approach
would
be
maintaining
concentration
within
normal
ranges,
but
this
can
quite
challenging
to
achieve.
Consequently,
diabetic
ulcers
usually
require
special
medical
care
prevent
such
as
sepsis,
amputation,
and
deformities,
which
these
patients.
Although
several
conventional
dressings,
hydrogels,
gauze,
films,
foams,
employed
treatment
chronic
wounds,
nanofibrous
scaffolds
gained
attention
researchers
because
their
flexibility,
ability
load
a
variety
bioactive
compounds
single
entities
or
combinations,
large
surface
area
volume
ratio,
provides
biomimetic
environment
for
cell
proliferation
relative
dressings.
Here,
we
present
current
trends
on
versatility
novel
platforms
incorporation
agents
suitable
enhancement
healing.
Journal of Drug Delivery Science and Technology,
Journal Year:
2024,
Volume and Issue:
96, P. 105689 - 105689
Published: April 21, 2024
In
the
last
few
years,
wound
healing
and
development
of
"ideal"
biomaterials
that
provide
quick
recovery
minimize
scarring
have
represented
one
most
important
priorities
researchers.
this
direction,
silk
fibroin
(SF)
scaffolds
gained
substantial
awareness,
as
a
promising
polymer
owing
to
their
increased
biocompatibility,
outstanding
mechanical
properties,
biodegradability,
especially
tensile
strength.
Furthermore,
SF
is
acknowledged
accelerate
process
by
encouraging
cell
growth
proliferation,
also
migration
different
types
cells
are
included
in
stages
process.
Therefore,
metal
oxide
nanoparticles
(NPs),
such
iron
(FeO),
copper
(CuO),
zinc
(ZnO),
or
magnesium
(MgO)
NPs,
been
extensively
researched
for
antimicrobial
properties
ability
enhance
tissue
regeneration
addition
SF.
When
introduced
within
scaffolds,
these
NPs
impart
enhanced
including
improved
scaffold
stability
durability.
Moreover,
presence
could
increase
biocompatibility
facilitating
adhesion,
migration,
ultimately
promoting
processes.
The
incorporation
other
natural
polymers
into
has
thus
emerged
favorable
method
therapeutic
potential
developed
biomaterial.
This
review
aims
an
overview
advancements
containing
applications.
