Cannabis sativa: A therapeutic medicinal plant-global marketing updates

World Journal of Biology Pharmacy and Health Sciences, Journal Year: 2024, Volume and Issue: 17(2), P. 170 - 183

Published: Feb. 14, 2024

Cannabis has been used for thousands of years recreational, medicinal, or religious purposes and the therapeutic potential medicinal was demonstrated in various medical conditions. The legalization is an important source economic growth as it contributes to growing revenue tax, creation new workplaces. maturity market varies across globe mainly due differing legal environments public attitudes towards Cannabis. Some countries such Canada United States have adopted fully regulated frameworks that allow cultivation, consumption, retail distribution products. Uruguay became first country world legalize production, consumption cannabis 2013. USA experiencing rapid country's recreational use. Regulations can also differ regarding how used. However, use, marketing Medical sativa (drug Marijuana type ) banned prohibited India presence high levels psychoactive principle THC (Narcotic drug). On other hand, Industrial (seed fiber type) Hemp legalized 2021 by Food Safety Standards Authority (FSSAI), Government India, New Delhi. In Azerbaijan, not available Recreational marijuana are illegal Azerbaijan. China. There still a huge prejudice society about its this scenario changing, social resistance decreasing use (Hemp) predicted experience substantial growth, with projections indicating will reach ₹US$100.80m 2024. worldwide projected US$60.79bn global size expected USD 73.6 billion 2027 anticipated expand at CAGR 18.1% during forecast period.

Language: Английский

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Role of Plant derived-medicine for controlling Cancer

International Journal of Science and Research Archive, Journal Year: 2024, Volume and Issue: 11(1), P. 2502 - 2539

Published: Feb. 28, 2024

This review paper has highlighted a list of plants containing active phytochemicals with anticancer potential, as well data supporting their use in cancer therapy, animal models, and pharmacological properties. Cancer is among the leading causes morbidity mortality worldwide. disease characterized by abnormal cell division proliferation that result from disruption molecular signals control these processes. abnormal, uncontrolled cells body. The when malignant, invade various parts body through bloodstream. spread its or tissue origin to another healthy part tissues organs called metastasis. Some regular characteristics cancers are apoptosis, angiogenesis, multiple replication, growth signal production, insensitivity anti-growth These features make have continuous growth, long time survival potential normal cells. Moreover, if activities not blocked, will continue increase, overwhelm finally kill patient cancer. Oncology study An oncologist doctor who treats provides medical care for person diagnosed may also be specialist. Today, despite considerable efforts, still remains an aggressive killer success rate therapies diminished toxicities, drug resistance, recurrence treatment failure. A significant challenge associated much art it science. Therefore, there constant demand develop new, effective, affordable drugs. Several factors, such environmental habitual activities, genetic etc., responsible Many patients seek alternative and/or complementary treatments because high death linked adverse side effects chemotherapy, radiation immunotherapy, surgery, stem therapy. Medicinal could possess effective compounds used adjuvants existing chemotherapy improve efficacy reduce drug-induced toxicity; chemotherapy-induced nausea vomiting patients’ quality life. Cell caused whole plant extracts via apoptosis. However, majority been researched prevention rather than treatment, resulting low uptake practice. Prevention certainly attractive management strategy. Thus might possible process carcinogenesis along lifestyle.

Language: Английский

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Pathogenic Escherichia coli (E. coli) food borne outbreak: Detection methods and controlling measures

Magna Scientia Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 10(1), P. 052 - 085

Published: Jan. 18, 2024

Food-borne illnesses and diseases are major threats to human health. Common food borne pathogens include bacteria such as Escherichia coli Serogroup (O157), Bacillus cereus, Clostridium botulinum, Campylobacter sp., C. perfringens, some Listeria monocytogenes, Salmonella spp., Shigella Staphylococcus aureus, Vibrio spp. etc. Pathogenic E. infection usually causes severe diarrhea. is the most common cause of acute urinary tract infections well sepsis. Diarrheagenic pathotypes can be passed in feces humans other animals. Safeguarding public health during mass gatherings a big challenge. Despite recent advances preservation techniques safety, significant disease outbreaks linked bacteria, fungi, viruses still occur worldwide indicating that these constitute risks However, at present conventional method for detection requires several days, especially cases where concentrations low. Enrichment commonly used bacterial isolation increase cell counts target bacteria. traditional culturing also slow laborious process requiring series steps may require use adjunct methods (e.g. biochemical, serological, nucleic acid-based conclusive identification) take up week The culture-based approaches coupled with PCR, immunoassays, bacteriophages, NGS, Biosensors, MALDI TOF MS increasingly being identification pathogens. Nucleic Real-Time PCR vPCR combined sequencing more widely than immunoassay NGS-based pathogen detection. Nanobiotechnology latest approach Bacteriophages one unique biological entity showed excellent host selectivity have been actively recognition probes Antibiotics efficient, powerful, treatment against pathogenic coli. Other ways treat or prevent contamination, probiotics, antimicrobial nanoparticles, radiation had reported.

Language: Английский

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Industrial Cannabis sativa-Hemp: Biochar applications and disadvantages

World Journal of Advanced Research and Reviews, Journal Year: 2023, Volume and Issue: 20(1), P. 371 - 383

Published: Oct. 14, 2023

This review paper highlights Industrial Cannabis sativa-Hemp uses and disadvantages particularly in the form of biochar. Biochar is defined as burning organic material at high temperature under limited oxygen supply to produce carbon rich known a carbon-rich product that formed pyrolysis different materials. Biochars were generally characterized by having porous nature large surface area. can provide nutrients soil directly because it contains nitrogen, phosphorous, potassium, magnesium, calcium. Progressive mineralization biochar releases inherent into soil. Hemp carbonized 800–1000°C displayed interesting electrical conductivity, opening opportunities for its use purposes. an important environmental management mitigate greenhouse gas emissions, such sequestration CO2 CH4, ozone-depleting N2O emissions. be utilised conditioner container substrate amendment agriculture horticulture. also has potential improve variety physical, chemical, biological qualities. However, there are some biochar, addition resulted pH plant growth was severely reduced, which might have obscured any potentially beneficial effect using however highlighted challenge growing media due difficulty maintaining adequate level growth.

Language: Английский

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Industrial Cannabis sativa: Hemp Plastic-Updates

World Journal of Advanced Research and Reviews, Journal Year: 2023, Volume and Issue: 20(1), P. 715 - 725

Published: Oct. 22, 2023

This review paper updates the benefits of using hemp fibre for production plastic. Traditional fossil-fuel based plastic emits massive levels greenhouse gasses, and material can take hundreds years to break down. Traditionally, plastics are made from petroleum-based compounds, which release toxic gases into atmosphere. Petroleum-based its by-product have a devastating effect on land, water, wildlife. Biodegradable produced petro-chemicals just like conventional except some additives included in their manufacturing helps them there fast degradation. Hemp is type biodegradable fibres, has sufficiently high cellulose concentration polymers. The resulting fully recyclable. It then be processed various products, including packaging, consumer goods, automotive parts, more plastics. 100% biodegradable, better alternative synthetic also lightweight, with an impressively density weight ratio. makes potentially good making lightweight components car aerospace industry. Conversely, minimize effect. offers great thermal, UV, dimensional stability. Some types resistant flame. solely extracted plant therefore, causes no toxicity during production.

Language: Английский

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Knowledge mapping for a secure and sustainable hemp industry: A systematic literature review

Case Studies in Chemical and Environmental Engineering, Journal Year: 2023, Volume and Issue: 9, P. 100550 - 100550

Published: Nov. 22, 2023

As a versatile and multipurpose plant, hemp (Cannabis sativa L.) possesses immense potential for its application in nutraceuticals, food nutrition, fibre, construction material. However, broader industrial potentials are hindered by the lack of sufficient knowledge on varietal differences, phytochemical properties, fibre processing techniques, bioenergy valorisation whole clinical evidence, standardised quality control mechanisms. In this context, we systematically reviewed 101 reviews 655 research papers to map what already know still need about hemp, across supply chain; from cultivar selection through production end use. We literature based major themes sub-themes. Existing spanned 33 sub-themes which can be classified under five broad themes: production, material, health, futures, education. The 'material' theme (42%) was most researched, followed 'production' (27%) 'health' (19%). At sub-theme level, one-fifth articles covered composite material (n = 139), analysis potency testing 45), hempcrete applications 43), germination plantation techniques 41). More than half selected were published last three years (2020–2022), concentrated mainly North America, Europe, China. Cannabidiol, seed oil considered as quick wins industry (hemp champions). Based our review, have discussed various gaps priorities chain, beginning early detection breed hurd residue address opportunities challenges development products.

Language: Английский

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Cannabis sativa: Cervical cancer treatment- Role of phytocannabinoids-A story of concern

World Journal of Biology Pharmacy and Health Sciences, Journal Year: 2024, Volume and Issue: 17(2), P. 253 - 296

Published: Feb. 20, 2024

This litrature review paper highlights the role of phytocannabinoids in controlling cervical cancer. Cervical cancer is one leading causes death among females worldwide. (CC) a malignant form tumor which originates cervix. cancer, develops woman’s cervix, second-most common women India The causative agent persistent infection with high-risk subtypes Human Papillomavirus (HPV) and E5, E6 E7 viral onco-proteins cooperate host factors to induce maintain phenotype. papillomavirus responsible for subclinical/clinical lesions HPV types 16 18 are most identified invasive Currently, recommended therapeutic regimens include chemotherapy, radiation therapy either alone or combination surgical interventions. However, they present several limitations including side effects ineffectiveness. Medicinal plants Cannabis sativa have been used decades health benefits treat different diseases has thousands years recreational, medicinal, religious purposes. Phytocannabinoids cannabinoids that occur naturally cannabis plant. two well known their properties are, Δ9-tetrahydrocannabinol (THC) Cannabidiol (CBD). hold big promise therapy. there need understand more about Endocannabinoid system (ECS) normal human physiology transformations. Molecular mechanisms regulation anticancer also be clarified. treatment durations existing trials concern. Future epidemiological clinical studies required further assess herbal medicines prevention In addition, preclinical trial evaluations not specifically conducted, so investigations related this warranted. Therefore, immunization programme best ideal solution eradication

Language: Английский

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Industrial Cannabis sativa: Hemp oil for biodiesel production

Magna Scientia Advanced Research and Reviews, Journal Year: 2023, Volume and Issue: 9(2), P. 022 - 035

Published: Nov. 12, 2023

This review paper highlights the production of biodiesel from hemp seed oil via transesterification reaction. Hemp seeds present a viable feedstock option for production. is demonstrated by plants high yield, ability to grow on infertile soil, resilience disease and bugs. performs well in blends. yield was calculated at 207 gallons/ha. higher than rapeseed soybeans oils but lower that palm oil. can meet ASTM D6751 EN 14214 requirements. exhibit poor kinematic viscosity oxidation stability. However, this easily be improved with use additives. Dilution/blending, micro-emulsification, pyrolysis, trans-esterification are four techniques applied solve problems encountered fuel viscosity. provides substantial environmental benefits. The amount emission reduction corresponds roughly blend rating fuel. may used an alternative highly controversial produced faces many perception legal challenges prevent wide-scale remains niche crop food supply chains, rendering it prohibitively expensive as Legalization increased improve cost producing subsequently biodiesel.

Language: Английский

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Biodiesel production: An updated review of evidence

International Journal of Biological and Pharmaceutical Sciences Archive, Journal Year: 2023, Volume and Issue: 6(2), P. 110 - 133

Published: Nov. 21, 2023

This review paper highlights the production of biodiesel from different plant based feedstocks via transesterification process. Biodiesel is a renewable, non-toxic, environment-friendly and an economically feasible option to tackle depleting fossil fuels its negative environmental impact. in general possess higher kinematic viscosity density than conventional diesel. However, because food security concerns, use edible oil criticized globally. Non-edible oils, waste cooking industry byproducts are suggested as effective nonedible feedstock does not compete with human consumption. High-potential second-generation for uses waist oil, acid animal tallow. Non crops India yellow oleander (Cascabela thevetia), Pongamia (Pongamia pinnata), Jatropha curcas, Mahua (Madhuca longifolia), Candlenut (Aleurites moluccanus), Rubber (Hevea brasiliensis), Soapnut (Sapindus mukorossi), Jojoba (Simmondsia chinensis), Tobacco (Nicotiana tabacum), Neem (Azadirachta indica), Karanja (Millettia Castor (Ricinus communis), Polanga (Calophyllum inophyllum L), Cotton (Gossypium), Kusum (Carthamus tinctorius), Yellow Sea mango (Cerbera odollam), Tung (Vernicia fordii), Bottle tree (Brachychiton rupestris). sustainable liquid bio-energy resource that might be used replace diesel fuel. Despite having numerous advantages over diesel, still struggling various reasons challenges like availability, high pricing, operational hurdles, supply-chain management challenges.

Language: Английский

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Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors

Open Access Research Journal of Biology and Pharmacy, Journal Year: 2024, Volume and Issue: 10(2), P. 028 - 071

Published: March 23, 2024

This review paper highlights and updates the role of plant based inhibitors in controlling triple-negative breast cancer (TNBC) via blocking TNBC signalling pathways. Breast is most common women. There are several identified types, among which fatal for patients. Conventionally, defined by lack estrogen receptor (ER), progesterone (PR), human epidermal 2 (HER2) cells. It well-known its metastatic, aggressive characteristics poor outcome clinic. Till today, treatment patients still a challenging task due to absence appropriate targets drugs. Despite successes emerging targeted therapies, relapse, recurrence, therapy failure rates significantly outpace other subtypes cancer. Mounting evidence suggests an accumulation resistant, Cancer Stem Cell (CSC) populations within TNBCs contributes clinical outcomes. These Cells enriched compared non-TNBC cancers. Approximately 60% drugs currently used have been isolated from natural products. Natural products treasure house development novel anticancer Many plant-derived compounds anti-cancer properties, including berberine quercetin, formononetin, calycosin, polyphenols, bioflavonoids, carotene, vitamins, andminerals. compounds, vinka alkaloids, vinblastine vincristine, luteolin, α-mangostin, piperine, silibinin, apigenin, fisetin, resveratrol, genistein, 10-gingerol, chalcones, curcumin, epigallocatechin gallate, cyanidin-3-O-glucoside, glycyrrhizin, shown especially TNBCs. Therefore, more trial data warranted further evaluation extracts

Language: Английский

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