Theriogenology, Journal Year: 2023, Volume and Issue: 215, P. 86 - 94
Published: Nov. 19, 2023
Language: Английский
Antioxidants, Journal Year: 2021, Volume and Issue: 10(7), P. 1096 - 1096
Published: July 8, 2021
Cooled preservation of semen is usually associated with artificial insemination and genetic improvement programs in livestock species. Several studies have reported an increase reactive oxidative species a decrease antioxidant substances sperm quality parameters during long-term storage at refrigerated temperatures. The supplementation antioxidants extenders before refrigeration could reduce this detrimental effect. Various been tested, both enzymatic, such as superoxide dismutase catalase, non-enzymatic, reduced glutathione, vitamins E C melatonin. However, the problem stress has not fully resolved. effects for semen-cooled reviewed depth. Therefore, objective present study was to review efficiency extender cooled
Language: Английский
Citations
61
Frontiers in Genetics, Journal Year: 2021, Volume and Issue: 12
Published: March 3, 2021
The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA methylation, histone modifications, chromatin remodeling, non-coding RNA species. Increasing lines of evidence support the concept that certain acquired traits are derived from environmental exposure during early embryonic fetal development, i.e., programming, can even be “memorized” in germline information transmitted to future generations. Advances technology now driving global profiling precise editing epigenomes, thereby improving our understanding regulation inheritance. These achievements open new avenues for development technologies or potential management interventions counteract adverse conditions improve performance livestock In this article, we review analyses (DNA modification, RNAs) germ cells embryos mammalian species (cattle, sheep, goats, pigs) determinants gamete embryo viability. We also discuss effects parental exposures on epigenetics gametes embryo, transgenerational inheritance livestock.
Language: Английский
Citations
43
IRAQI JOURNAL OF AGRICULTURAL SCIENCES, Journal Year: 2024, Volume and Issue: 55(Special), P. 206 - 216
Published: Jan. 25, 2024
This study was investigated the relationship between Holstein bulls' fertility with some biomarkers (amino، fatty، and organic acids) semen characteristics. The included exploring among of bulls، several biomarkers، characteristics in straws (20-25 straws/bull) preserved for three years. cows were artificially inseminated (9-10 cows/bull) from semen. Based on rate، bulls divided into groups، first medium (˂65%)، second good (65-79%)، third high (>80%). evaluated، concentration amino acids fatty measured seminal plasma using gas chromatography HPLC. results revealed significant differences rate different groups favor highly fertile bulls. did not show any most semen، except a increase percentage live sperm compared to ones. There no all concentrations carboxylic concentrations، an glycine acid (P˂0.05) decrease omega 9 In conclusion، omega-9 can be regarded as their level (volatile adopted indicator quality or energy diet
Language: Английский
Citations
6
Frontiers in Veterinary Science, Journal Year: 2021, Volume and Issue: 8
Published: June 22, 2021
Bull fertility is an important economic trait in sustainable cattle production, as infertile or subfertile bulls give rise to large losses. Current methods assess bull are tedious and not totally accurate. The massive collection of functional data analyses, including genomics, proteomics, metabolomics, transcriptomics, epigenomics, helps researchers generate extensive knowledge better understand the unraveling physiological mechanisms underlying subpar male fertility. This review focuses on sperm phenomes genome epigenome that associated with Findings from multiple sources were integrated new transferable applied andrology. Diverse encompassing analyses molecular cellular dynamics fertility-associated molecules conventional parameters can be considered effective approach determine for efficient production. In addition gene expression information, we also provide methodological which rigor reliability studies. Fertility a complex influenced by several factors has low heritability, although heritability scrotal circumference high it known maker. There need levels functions RNA, proteins, metabolites. shed light additional markers used combination predict breeding bulls. provides comprehensive characteristics phenotypes
Language: Английский
Citations
40
Journal of Proteomics, Journal Year: 2022, Volume and Issue: 273, P. 104791 - 104791
Published: Dec. 17, 2022
Language: Английский
Citations
23
Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11
Published: May 10, 2024
It is critical in sheep farming to accurately estimate ram fertility for maintaining reproductive effectiveness and production profitability. However, there currently a lack of reliable biomarkers semen quality fertility, which hindering advances animal science technology. The objective this study was uncover long non-coding RNAs (lncRNAs) sperm from rams with distinct phenotypes. Mature were allocated into two groups: high low (HF; n = 31; 94.5 ± 2.8%, LF; 25; 83.1 5.73%; P 0.028) according the pregnancy rates sired by (average rate; 89.4 7.2%). Total isolated highest- lowest-fertility ( 4, 99.2 1.6%, 73.6 4.4%, respectively) followed next-generation sequencing transcripts. We uncovered 11,209 lncRNAs HF LF. In comparison each other, 93 differentially expressed (DE) Of these, 141 mRNAs upregulated 134 downregulated between LF, respectively. Genes commonly enriched 9 + 2 motile cilium flagellum ABHD2, AK1, CABS1, ROPN1, SEPTIN2, SLIRP , TEKT3 . Moreover, CCDC39, CFAP97D1, SLIRP, TTC12 flagellated motility motility. Differentially top 16 KEGG pathways. Targets elucidate functions cis trans manner using genetic context lncRNA locus, sequences revealed 471 targets 10 lncRNAs. This illustrates existence potential that can be implemented analyzing determining used breeding soundness exams precision livestock ensure food security on global scale.
Language: Английский
Citations
4
Theriogenology, Journal Year: 2025, Volume and Issue: 235, P. 262 - 274
Published: Jan. 17, 2025
Language: Английский
Citations
0
Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16
Published: Jan. 27, 2025
Background Asthenozoospermia is a common cause of male infertility. Studies have shown that sperm quality and motility are affected by the gut–testis axis can regulate testicular metabolism function through gut microbiota its metabolites. Acupuncture an important modality complementary alternative medicine. It improve motility, but it remains unclear whether acupuncture enhance vitality influencing axis. Methods In this study, quality, pathology, serum hormone levels were assessed using cyclophosphamide-induced mouse model. Real-time PCR, western blot analysis, immunofluorescence techniques used to assess effects on barrier blood–testis functions. addition, microbiome metabolomics study impact structure, serum, metabolites in asthenozoospermic mice. Further validation was obtained performing fecal transplantation (FMT). Results improved quality; ameliorated pathology; increased testosterone (T), follicle-stimulating (FSH), luteinizing (LH) levels; repaired damage The abundances Bacteroidota, Firmicutes, Faecalibaculum, Dubosiella associated with as analysis. Serum revealed differentially expressed (DEMs), such cytosine N-oleyl-leucine, closely related motility. Testicular analysis DEMs, 5-fluorouridine 1-acetylimidazole, also Furthermore, reproductive improvements mice achieved via FMT. Conclusion may alleviate asthenozoospermia symptoms modulating repairing barrier.
Language: Английский
Citations
0
Animal Reproduction Science, Journal Year: 2025, Volume and Issue: 275, P. 107800 - 107800
Published: Feb. 20, 2025
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141894 - 141894
Published: March 1, 2025
Language: Английский
Citations
0