Effect of Consumption of Extravirgin Olive Oil on the Lipid Profile and on the Glycemia of Children with Cystic Fibrosis Seen at a Specialized Center in Belém-PA/ Brazil DOI Open Access

Cláudia Cruz Barbosa,

Izabella Syane Oliveira Pereira,

Clyvia Wanessa Góes Santos

et al.

International Journal of Advanced Engineering Research and Science, Journal Year: 2022, Volume and Issue: 9(10), P. 115 - 124

Published: Jan. 1, 2022

Introduction: Cystic fibrosis (CF) is a genetic disease that affects the cystic transmembrane conductance regulatory protein (CFTR), which functions as chlorine channel regulating balance between ions and water across epithelium. Nutrition has shown an important role in this problem due to need for differentiated dietary prescription through hypercaloric hyperlipidic diet associated with anthropometric monitoring, food strategy extra virgin olive oil can bring several benefits its rich composition acids. monounsaturated fatty acids (MUFA) their bioactive compounds considered nutraceuticals, capable of modulating gene expression, interfering production proteins metabolites; It anti-inflammatory, antioxidant antimicrobial effects. Method: A clinical trial was carried out children aged 2 11 years attended at João de Barros Barreto University Hospital, age there were 20 children, could not be contacted 3 refused participate, so research had 15 individuals, exposure group (n=8) received monitoring three months control (n=7) standard nutritional guidance disease. The variables were: lipid profile (total cholesterol, HDL, LDL triglycerides), glycemic status (fasting glucose). Results: There reduction rates fasting glucose (p=0.0355) triglycerides (p=0.0157) significant difference when comparing intervention groups. Discussion: no other study found using ingestion pure people fibrosis, only studies mixture soy or docosahexaenoic acid, however, regarding healthy population diseases, tests demonstrate benefit reducing these rates. Conclusion: Supplementation proved effective, however factors influence health such lifestyle habits, general individual variants, longer intake time greater number participants, preferably multicenter, should evaluated, but another tool aggregate various measures improve quality life population.

Language: Английский

Is There More to Olive Oil than Healthy Lipids? DOI Open Access

Akritas Isaakidis,

Jane El Maghariki,

Sérgio Carvalho-Barros

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(16), P. 3625 - 3625

Published: Aug. 18, 2023

The Mediterranean diet is a healthy dietary pattern whose main characteristic olive oil consumption. potential health benefits of have been extensively investigated and the present review provides more recent clinical evidence supporting positive impact intake on human health. PubMed (n = 227) Scopus 308) databases were searched for published studies in English over past six years (October 2016 to December 2022), following key word searches "olive oil" "health". Major findings associated with antioxidant anti-inflammatory effects, improvement endothelial function lipid profile, prevention obesity, diabetes, cardiovascular neurodegenerative diseases, modulation gut microbiota. These are attributed nutritional composition oil, which has high content monounsaturated fatty acids (MUFA) (oleic acid particular) minor compounds such as polyphenols (oleuropein hydroxytyrosol). Although additional research continues be required, recently generated supports contribute beneficially management variety non-communicable consequence synergism between its components' complexity.

Language: Английский

Citations

17
The Role of Nutraceuticals and Probiotics in Addition to Lifestyle Intervention in the Management of Childhood Obesity—Part 1: Metabolic Changes DOI Open Access
Maria Elisabeth Street,

Federica Casadei,

Erika Rita Di Bari

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(10), P. 1630 - 1630

Published: May 9, 2025

Childhood obesity is a growing global health issue. Its rising prevalence linked to genetic, environmental, and lifestyle factors. Obesity in children could lead different comorbidities complications with an increased risk of metabolic disorders, such as insulin resistance, dyslipidemia, type 2 diabetes mellitus (T2DM), dysfunction-associated steatotic liver disease (MASLD). First-line treatment involves dietary modifications changes; however, adherence often poor remains significant challenge. Pharmacotherapy, while potential option, has limitations availability can cause side effects, leading interest alternative treatments, nutraceutical compounds. Derived from natural sources, these compounds have anti-inflammatory, antiallergic, antioxidant, antibacterial, antifungal, neuroprotective, antiaging, antitumor, insulin-sensitizing, glucose, lipid-lowering effects. This review describes commonly used compounds, omega-3 fatty acids, vitamin D, polyphenols (such resveratrol curcumin), berberine, white mulberry leaves others, pre- probiotics the management obesity, evaluating evidence on their mechanisms action efficacy comorbidities. The suggests that integration nutraceuticals into diet may positively influence body mass index, glucose metabolism, lipid profiles, gut microbiota composition reduce inflammation obese individuals. These effects provide future practical guidance for clinical practice, contribute improvement, potentially prevent obesity-related complications. In this first part, we discuss sensitivity T2DM, MASLD addition interventions.

Language: Английский

Citations

0
Polyphenol hydroxytyrosol present olive oil improves skin wound healing of diabetic mice DOI

Matheus Silva Duarte,

Victor Müller Fuhro,

Jeane de Souza Nogueira

et al.

Wound Repair and Regeneration, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Abstract The imbalance in oxidant production and chronic inflammation are the main mechanisms that lead to detrimental effects of diabetes on skin wound healing. Thus, administration antioxidants could improve diabetic This study aimed understand extra virgin olive oil (EVOO) or hydroxytyrosol (HT) healing under conditions. Skin wounds streptozotocin‐induced mice were topically treated with HT. Some animals fed a diet rich EVOO. Wounds harvested 7 days later. In vitro assays, fibroblasts macrophages high levels glucose EVOO HT promoted closure collagen deposition mouse wounds. reduced number infiltrated neutrophils, tumour necrosis factor‐α, lipid peroxidation, nuclear factor erythroid 2‐related 2 also increased anti‐inflammatory phenotype interleukin‐10 fibroblast migration, gel contraction, switched an conclusion, supplementation topical application promotes conditions can be possible therapeutic tool for treatment those lesions.

Language: Английский

Citations

3
Body composition assessment in individuals with class II/III obesity: a narrative review DOI Creative Commons
Érika Aparecida Silveira, Maria Clara Rezende Castro,

Andréa de Fátima Silva Rezende

et al.

BMC Nutrition, Journal Year: 2024, Volume and Issue: 10(1)

Published: Oct. 22, 2024

Individuals with class II/III obesity have a high percentage of body fat. Assessing composition in cases severe can be difficult and controversial both clinical practice scientific research. Thus, it is essential to explore the different aspects evaluating discuss available methods assess this population.

Language: Английский

Citations

3
Effect of Self-Directed Management Implementation on Short-Term Complications among Patients with Type II Diabetes Mellitus DOI Open Access

Abeer El Said Hassan El Sol,

Nahid Elgahsh,

Tarek Abdl-Rahaman

et al.

Menoufia Nursing Journal, Journal Year: 2023, Volume and Issue: 8(2), P. 235 - 257

Published: June 1, 2023

According to the World Health Organization (WHO), primary component of patientcentered treatment is self-management practices, which serves as foundation for management diabetes mellitus.Purpose: examine effect self-directed implementation on short-term complications among patients with type II diabetic patients.Design: Quasi Experimental design.Setting: The outpatient medical clinic Menoufia University Hospital in Egypt.Sampling: A consecutive sample, included 240 persons Type Diabetes Mellitus, sample was selected randomly assign them into 120 each group; control group, while study group divided subtype groups (study1 and study2) 60 patient group.Instruments: Three instruments used collect current data; Instrument (I): Mellitus Structured Questionnaire; (II): Bio physiological measurements.Instrument (III): Patient's self-practices management.Results: existing outcomes recorded that; study2, who implemented practices olive oil have been associated better improvement all lab investigations blood glucose 146.33± 25.74, 167.17 ± 46.28 & 266.94± 63.27 respectively; study1 furthermore high density (HDL) study2 65.90± 2.72 if compared 62.68 4.04& also decreasing low-density lipoprotein (LDL) than other (94.63± 3.31, 96.40 3.35&153.39±13.99) highly significance difference studied short term frequency after application selfmanagement (study2 study1&control group).Conclusion: concluded that implementing directed part a health dietary plan likely produce reduce when combined physical exercise.Recommendation: Replicate another setting using larger size generalize search results.Self-management program can be applied hospital routine care diabetes.

Language: Английский

Citations

0
Effect of Consumption of Extravirgin Olive Oil on the Lipid Profile and on the Glycemia of Children with Cystic Fibrosis Seen at a Specialized Center in Belém-PA/ Brazil DOI Open Access

Cláudia Cruz Barbosa,

Izabella Syane Oliveira Pereira,

Clyvia Wanessa Góes Santos

et al.

International Journal of Advanced Engineering Research and Science, Journal Year: 2022, Volume and Issue: 9(10), P. 115 - 124

Published: Jan. 1, 2022

Introduction: Cystic fibrosis (CF) is a genetic disease that affects the cystic transmembrane conductance regulatory protein (CFTR), which functions as chlorine channel regulating balance between ions and water across epithelium. Nutrition has shown an important role in this problem due to need for differentiated dietary prescription through hypercaloric hyperlipidic diet associated with anthropometric monitoring, food strategy extra virgin olive oil can bring several benefits its rich composition acids. monounsaturated fatty acids (MUFA) their bioactive compounds considered nutraceuticals, capable of modulating gene expression, interfering production proteins metabolites; It anti-inflammatory, antioxidant antimicrobial effects. Method: A clinical trial was carried out children aged 2 11 years attended at João de Barros Barreto University Hospital, age there were 20 children, could not be contacted 3 refused participate, so research had 15 individuals, exposure group (n=8) received monitoring three months control (n=7) standard nutritional guidance disease. The variables were: lipid profile (total cholesterol, HDL, LDL triglycerides), glycemic status (fasting glucose). Results: There reduction rates fasting glucose (p=0.0355) triglycerides (p=0.0157) significant difference when comparing intervention groups. Discussion: no other study found using ingestion pure people fibrosis, only studies mixture soy or docosahexaenoic acid, however, regarding healthy population diseases, tests demonstrate benefit reducing these rates. Conclusion: Supplementation proved effective, however factors influence health such lifestyle habits, general individual variants, longer intake time greater number participants, preferably multicenter, should evaluated, but another tool aggregate various measures improve quality life population.

Language: Английский

Citations

0