Introdução:
Os
exercícios
físicos
são
benéficos
para
as
pessoas
com
doença
de
Parkinson
(DP)
em
diferentes
desfechos,
no
entanto,
os
parâmetros
prescrição
do
exercício
físico
[frequência,
intensidade,
tempo
(durante
a
sessão
e
quantidade
sessões),
tipo
progressão
-FITT(P)]
não
estão
sistematizados.Além
disso,
efeitos
das
modalidades
base
nos
componentes
da
Classificação
Internacional
Funcionalidade,
Incapacidade
Saúde
(CIF)
precisam
ser
mais
claros
na
literatura.Objetivo:
Descrever
treinamento
(FITT(P))
incluídas
(força,
marcha,
equilíbrio,
aeróbio
multimodal),
investigar
desfechos
classificá-los
segundo
CIF,
além
magnitude
efeito
estudos
alta
qualidade
metodológica
indivíduos
DP.Método:
A
revisão
foi
registrada
PROSPERO
(#CRD42021248890).Foram
utilizadas
bases
dados
PubMed,
Embase,
Web
of
Science
SPORT
Discuss
desde
primeira
data
encontrada
até
março
2023.A
escala
PEDro
utilizada
analisar
o
risco
viés
dos
estudos.Estudos
pontuados
abaixo
seis
foram
excluídos
metanálise.Resultados:
Foram
encontrados
20.065
busca
inicial.Após
triagem
aplicação
critérios
elegibilidade,
81
incluídos
(33
força,
19
13
8
aeróbio,
32
multimodalum
estudo
incluído
três
22
duas
modalidades),
totalizando
4.865
incluídos.Quarenta
quatro
classificados
como
baixo
viés.Com
relação
aos
princípios
FITT(P),
frequência
variou
2
4
vezes
por
semana;
intensidade
maioria
entre
leve
moderada;
dependentes
treinamento,
sendo
realizada
pouco
estudos;
minutos
horas
cada
sessão,
24
semanas
intervenção.Na
metanálise,
encontramos
um
superior
ao
força
Estrutura
Função
Corpo
CIF
(flexibilidade,
preensão
manual,
pico
torque
extensores
joelho)
Atividade
(velocidade
marcha
rápida
mobilidade
funcional);
treino
equilíbrio
comprimento
passada,
componente
CIF.A
multimodal
mostraram
superiores
comparação
intervenção
controle
nenhum
desfecho.Não
possível
executar
metanálise
devido
restrita
mesmos
desfechos.Conclusão:
FITT(P)
variaram
consideravelmente
estudos.Efeitos
melhora
membros
inferiores,
funcional
velocidade
passada
DP.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(17), P. 22303 - 22311
Published: April 16, 2024
The
advancement
of
artificial
intelligent
vision
systems
heavily
relies
on
the
development
fast
and
accurate
optical
imaging
detection,
identification,
tracking.
Framed
by
restricted
response
speeds
low
computational
efficiency,
traditional
optoelectronic
information
devices
are
facing
challenges
in
real-time
tasks
their
ability
to
efficiently
process
complex
visual
data.
To
address
limitations
current
devices,
this
study
introduces
a
novel
photomemristor
utilizing
halide
perovskite
thin
films.
fabrication
involves
adjusting
iodide
proportion
enhance
quality
films
minimize
dark
current.
exhibits
high
external
quantum
efficiency
over
85%,
which
leads
energy
consumption
0.6
nJ.
spike
timing-dependent
plasticity
characteristics
device
leveraged
construct
spiking
neural
network
achieve
99.1%
accuracy
rate
directional
perception
for
moving
objects.
notable
results
offer
promising
hardware
solution
efficient
optoneuromorphic
edge
computing
applications.
European Journal of Translational Myology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 11, 2024
The
primary
aim
of
this
study
was
to
systematically
review
and
meta-analyze
the
impact
sensorimotor
proprioceptive
exercises
on
balance
in
older
adults.
We
also
sought
define
how
researchers
describe
sensory-motor
training
their
respective
protocols.
conducted
following
PRISMA
guidelines,
with
searches
performed
March
2023.
Both
authors
carried
out
independent
using
PubMed
PEDro
databases.
From
a
total
320
identified
records,
12
studies
were
deemed
eligible
for
meta-analysis
after
screening
removal
duplicates.
average
score
5.11
±
1.11
indicating
overall
fair
quality
studies.
Common
outcome
measures
included
Berg
scale,
Timed
up
go
test,
Tinetti
Functional
reach
test
various
single-leg
stance
tests.
All
outcomes
significantly
improved
by
interventions
(standard
mean
difference
=
0.65
–
1.29),
little
between
training.
However,
evidence
ranged
from
“very
low”
“low”
based
GRADE
suggesting
further
high-quality
are
needed.
This
underscores
potential
benefits
enhancing
adults,
while
highlighting
ambiguity
inconsistency
regarding
usage
terms
Brain,
Journal Year:
2022,
Volume and Issue:
145(12), P. 4531 - 4544
Published: Sept. 5, 2022
Associative
plasticity
occurs
when
two
stimuli
converge
on
a
common
neural
target.
Previous
efforts
to
promote
associative
have
targeted
cortex,
with
variable
and
moderate
effects.
In
addition,
the
circuits
are
inferred,
rather
than
tested
directly.
contrast,
we
sought
target
strong
convergence
between
motor
sensory
systems
in
spinal
cord.
We
developed
cord
plasticity,
precisely
timed
pairing
of
cortex
dorsal
stimulations,
this
interaction.
hypothesis
that
properly
paired
stimulation
would
strengthen
sensorimotor
connections
improve
recovery
after
injury.
physiological
effects
stimulation,
pathways
mediate
it,
its
function
preclinical
trial.
Subthreshold
strongly
augmented
evoked
muscle
potentials
at
time
they
were
paired,
but
only
arrived
synchronously
This
effect
depended
both
cortical
descending
proprioceptive
afferents;
selective
inactivation
either
these
fully
abrogated
effect.
Spinal
repetitive
for
5
or
30
min
awake
rats,
increased
excitability
hours
ended.
To
apply
as
therapy,
optimized
parameters
long-lasting
was
just
rats
cervical
injury
uninjured
demonstrating
spared
sufficient
support
plasticity.
blinded
trial,
received
C4
contusive
Ten
days
injury,
randomized
each
day
10
sham
stimulation.
Rats
had
significantly
improved
primary
outcome
measure,
test
dexterity
during
manipulation
food,
50
persistently
stronger
responses
indicating
locus
After
near
normalization
H-reflex
modulation.
The
groups
no
difference
rat
grimace
scale,
measure
pain.
conclude
strengthens
within
cord,
resulting
partial
reflex
modulation
forelimb
Since
performed
routinely
humans,
approach
can
be
trialled
people
other
disorders
damage
impair
dexterity.
Frontiers in Human Neuroscience,
Journal Year:
2025,
Volume and Issue:
19
Published: Feb. 6, 2025
Understanding
how
the
brain
encodes
upper
limb
movements
is
crucial
for
developing
control
mechanisms
in
assistive
technologies.
Advances
technologies,
particularly
Brain-machine
Interfaces
(BMIs),
highlight
importance
of
decoding
motor
intentions
and
kinematics
effective
control.
EEG-based
BMI
systems
show
promise
due
to
their
non-invasive
nature
potential
inducing
neural
plasticity,
enhancing
rehabilitation
outcomes.
While
BMIs
intention
kinematics,
studies
indicate
inconsistent
correlations
with
actual
or
planned
movements,
posing
challenges
achieving
precise
reliable
prosthesis
Further,
variability
predictive
EEG
patterns
across
individuals
necessitates
personalized
tuning
improve
efficiency.
Integrating
multiple
physiological
signals
could
enhance
precision
reliability,
paving
way
more
strategies.
Studies
have
shown
that
activity
adapts
gravitational
inertial
constraints
during
movement,
highlighting
critical
role
adaptation
biomechanical
changes
creating
devices.
This
review
aims
provide
a
comprehensive
overview
recent
progress
deciphering
associated
both
assisted
avenues
future
exploration
neurorehabilitation
brain-machine
interface
development.
Clinical Neurophysiology,
Journal Year:
2025,
Volume and Issue:
173, P. 113 - 123
Published: March 9, 2025
To
explore
the
excitability
and
sensory
motor
integration
of
face
masticatory
primary
cortex
(M1),
recognition
expressions
in
individuals
with
dentofacial
deformities
(IDD).
Short-interval
intracortical
inhibition
(SICI),
short-afferent
(SAI)
M1,
blink
reflex
(FER)
ability
were
assessed
18
healthy
subjects
(HS)
(24.56
±
1.02
years
old)
IDD
(27.36
1.39
years)
before
after
1
month
from
surgery.
In
IDD,
SICI
(p
=
0.033)
SAI
0.008)
significantly
reduced
masticatory,
but
not
face,
M1
was
normal.
also
exhibited
deficits
FER
surgery
0.033),
which
still
present
0.015),
although
improved.
Results
evidence
that
alterations
afferents
due
to
modulates
sensorimotor
topographic
specificity.
The
altered
information
only
influences
inhibitory
control
FER.
inputs
outputs
depends
topographically
on
type
stimulated
as
well
target
muscle
its
respective
representation
area
M1.
Afferent
plays
a
role
ability.
European Journal of Investigation in Health Psychology and Education,
Journal Year:
2025,
Volume and Issue:
15(4), P. 50 - 50
Published: April 1, 2025
Background:
Physical
activity
(PA)
plays
a
crucial
role
in
improving
the
quality
of
life
(QoL)
older
people,
particularly
by
enhancing
their
balance
and
movement
coordination.
Objective:
This
study
aimed
to
assess
effects
sensorimotor
training
intervention
adults.
Methods:
A
total
90
participants,
divided
into
Control
Group
(n
=
44)
Experimental
46)
were
involved
24-week
program.
The
physical
capacities
participants
assessed
both
before
after
Strength
flexibility
measured
using
“Rikli
Jones”
protocol
(1999),
while
agility
speed
through
“Timed-up-and-go”
tests.
Taking
account
participants’
gender,
descriptive
analysis
sample
was
conducted
describe
data
mean
standard
deviation.
Student’s
T
test
performed
compare
differences
between
groups
according
first
second
collection
moments
(before
intervention).
Jamovi
software
(v.
2.5.2.0)
used
develop
statistical
analysis,
p-value
less
than
0.05
significance.
Results:
showed
significant
improvements
across
all
analyzed
variables
following
(p
<
0.005),
indicating
substantial
gains
capacities.
In
contrast,
“sitting
reaching”
did
not
show
difference
highlighting
lack
improvement
without
intervention.
According
effect
size
sample,
it
observed
that
parameters
“reach
behind
your
back
(right)”
(left)”
highest
comparing
(ES:
0.60,
0.71).
Conclusions:
findings
highlight
practical
clinical
impact
implementing
tailored
programs
for
Such
interventions
are
critical
QoL,
reducing
risk
falls,
injuries,
chronic
illnesses,
promoting
overall
health,
independence,
well-being.
Integrating
routine
care
people
can
support
healthy
aging
functional
independence.
Frontiers in Neurology,
Journal Year:
2025,
Volume and Issue:
16
Published: April 4, 2025
Background
Existing
rehabilitation
techniques
are
not
satisfactory
in
improving
motor
function
after
stroke,
resulting
heavy
social
burdens.
With
discovery
of
mirror
neuron
system
(MNS),
action
observation
(AO)
has
become
a
promising
strategy
to
promote
learning
rehabilitation.
Based
on
MNS
theory
and
virtual
reality
(VR)
technology,
we
designed
an
innovative
rehabilitative
approach:
synchronous
360°
VR
video
AO
(VRAO)
neuromuscular
electrical
stimulation
(NMES).
We
hypothesized
that
VRAO+NMES
could
enhance
activation,
thus
improve
upper
limb
activities
daily
living
stroke
survivors.
Methods
To
explore
the
efficacy
mechanism
VRAO+NMES,
this
single
center,
evaluator
blinded,
prospective,
two
arm
parallel
group
randomized
controlled
trial
with
1:1
allocation
ratio.
The
experiment
will
receive
while
control
landscape
combined
NMES.
Fugl-Meyer
Assessment
for
Upper
Extremity
is
primary
outcome
study,
Brunstrom
Recovery
Stages
Extremity,
Manual
Muscle
Test,
Range
Motion,
Modified
Barthel
Index,
Functional
Independence
Measure
secondary
outcomes.
In
addition,
functional
near-infrared
spectroscopy
(fNIRS)
surface
electromyography
(sEMG)
be
used
evaluate
activation
brain
regions
related
muscles,
respectively.
Discussion
Applying
therapy
(AOT)
popular,
another
study
direction
AOT
combine
it
peripheral
stimulations
simultaneously.
Due
its
full
immersive
characteristic
multi-sensory
input,
videos
based
motivation
engagement
level
participants.
fNIRS
sEMG
test
results
may
act
as
good
biomarkers
predict
outcomes,
helping
select
suitable
candidates
new
intervention.
Conclusion
provide
evidence
feasibility
potential
clinical
rehabilitation,
applicability
generalize
use
hospital,
community,
home
settings.
Clinical
registration
https://www.chictr.org.cn/showproj.html?proj=178276
,
Identifier
[ChiCTR2200063552].
Applied Sciences,
Journal Year:
2025,
Volume and Issue:
15(9), P. 4762 - 4762
Published: April 25, 2025
Postural
control
arises
from
the
complex
interplay
of
stability,
adaptability,
and
dynamic
adjustments,
which
are
disrupted
post-stroke,
emphasizing
importance
examining
these
mechanisms
during
functional
tasks.
This
study
aimed
to
analyze
complexity
variability
postural
in
post-stroke
individuals
feedforward
phase
gait
initiation.
A
cross-sectional
analyzed
17
16
matched
controls.
Participants
had
a
unilateral
ischemic
stroke
chronic
could
walk
independently.
Exclusions
included
cognitive
impairments,
recent
surgery,
neurological/orthopedic
conditions.
Kinematic
kinetic
data
were
collected
10
self-initiated
trials
centre
pressure
(CoP)
dynamics
joint
angles
(−600
ms
+50
ms).
12-camera
motion
capture
system
(Qualisys,
Gothenburg,
Sweden)
recorded
full-body
kinematics
using
72
reflective
markers
placed
on
anatomical
landmarks
lower
limbs,
pelvis,
trunk,
upper
limbs.
Ground
reaction
forces
measured
via
force
plates
(Bertec,
Columbus,
OH,
USA)
compute
CoP
variables.
Linear
(displacement,
amplitude,
velocity)
non-linear
(Lyapunov
exponent—LyE
multiscale
entropy—MSE)
measures
applied
assess
variability.
Mann–Whitney
U
tests
(p
<
0.05).
The
group
showed
greater
displacement
0.05)
reduced
velocity
=
0.021).
Non-linear
analysis
indicated
LyE
values
adaptability
position
amplitude
across
scales
In
sagittal
plane,
higher
head,
with
MSE
Frontal
plane
findings
increased
ankle,
transverse
exaggerated
rotational
patterns
observed
hip,
alongside
convergence
Stroke
survivors
exhibit
linear
variability,
indicating
instability,
complexity,
reflecting
limited
adaptability.
These
results
highlight
need
for
rehabilitation
strategies
that
address
both
stability
time
scales.
Frontiers in Human Neuroscience,
Journal Year:
2022,
Volume and Issue:
16
Published: March 25, 2022
Several
investigations
have
addressed
the
process
of
balance
adaptation
to
external
perturbations.
The
during
unperturbed
stance
has
received
little
attention.
Further,
whether
current
sensory
conditions
affect
rate
not
been
established.
We
role
vision
and
haptic
feedback
on
while
standing
foam.In
22
young
subjects,
analysis
geometric
(path
length
sway
area)
spectral
variables
(median
frequency
mean
level
both
total
spectrum
selected
windows)
oscillation
centre
feet
pressure
(CoP)
identified
effects
vision,
light-touch
(LT)
or
in
anteroposterior
(AP)
mediolateral
(ML)
direction
over
8
consecutive
90
s
trials.Adaptation
was
obvious
without
(eyes
closed;
EC)
tenuous
with
open;
EO).
With
trial
repetition,
path
median
diminished
EC
(p
<
0.001)
area
increased
0.001).
low-
high-frequency
range
decreased
AP
ML
directions,
respectively.
Touch
compared
no-touch
enhanced
increase
low-frequency
power
0.05).
Spectral
differences
distinct
persisted
after
adaptation.Balance
occurs
foam.
Adaptation
leads
a
progressive
amplitude
lowest
frequencies
concurrent
decrease
range.
Within
this
common
behaviour,
touch
adds
its
stabilising
action
modest
effect
rate.
Stabilisation
is
improved
by
favouring
slow
oscillations
at
expense
minimisation.
These
findings
are
preliminary
problems
persons
deficits,
ageing,
peripheral
central
nervous
lesion.