Comparative antioxidant activity and phytochemical content of five extracts of Pleurotus ostreatus (oyster mushroom)

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 15, 2024

Abstract Reactive oxygen species reacts with numerous molecules in the body system causing oxidative damage, which requires antioxidants to ameliorate. Pleurotus ostreatus , a highly nutritious edible mushroom, has been reported be rich bioactive compounds. This study evaluated comparative antioxidant activity and phytochemical contents of five extracts P. : aqueous (AE), chloroform (CE), ethanol (EE), methanol (ME) n-hexane (HE). The composition were determined using standard in-vitro assay methods. Results showed that contained alkaloids, tannins, saponins, flavonoids, terpenoids, phenolics, cardiac glycosides, carbohydrates, anthrocyanins, betacyanins varied amounts. CE had highest flavonoid content (104.83 ± 29.46 mg/100 g); AE gave phenol 24.14 0.02 g; tannin was EE (25.12 0.06 HE amounts alkaloids (187.60 0.28 g) saponins (0.16 0.00 g). Antioxidant analyses revealed best hydroxyl radical 250% at 100 µg/ml ferric cyanide reducing power 8495 µg/ml; ME maximum DPPH (87.67%) hydrogen peroxide scavenging (65.58%) 500 nitric oxide inhibition 65.81% ascorbate peroxidase 1.60 (iU/l). total capacity (5.27 GAE µg/ml) ferrous iron chelating (99.23% while guaiacol 0.20(iU/l). characteristics (IC 50 ) followed order: > HE. Overall, extraction solvent for . high phenolic compounds, makes it source potential candidate development new therapies variety stress-related disorders.

Language: Английский

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Mushrooms in innovative food products: challenges and potential opportunities as meat substitutes, snacks and functional beverages

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 104868 - 104868

Published: Jan. 1, 2025

Language: Английский

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The Influence of Substrate and Strain on Protein Quality of Pleurotus ostreatus

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(10), P. 4040 - 4040

Published: May 9, 2024

Background: The effect of substrate and strain on the nutritional functional properties mushroom flours protein concentrates (PCs) has not thoroughly been investigated. Methods: proteins P. ostreatus (strains AMRL144 150) were isolated following alkaline extraction (pH 12) isoelectric precipitation 4) as it was determined by solubility curves. quality PCs evaluated determining index (PSI) their properties, such water (WAC) oil absorption capacity (OAC), foam (FC), stability (FS) emulsion (ES). amino acid (AA) composition reversed-phase liquid chromatography after hydrolysis o-phthalaldehyde derivatization. Results: PSIs comparable to those soy concentrates. highest AA concentration found for both strains when cultivated barley oat straw (BOS) substrate, showing a similar trend content. A principal component analysis (PCA) indicated an impact properties. Conclusions: Both can produce high especially wheat (WS). FS positively correlated with AMRL150 whereas FC AMRL144.

Language: Английский

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In silico evaluation of potential breast cancer receptor antagonists from GC-MS and HPLC identified compounds in Pleurotus ostreatus extracts

RSC Advances, Journal Year: 2024, Volume and Issue: 14(33), P. 23744 - 23771

Published: Jan. 1, 2024

Introduction: Pharmacotherapeutic targets for breast cancer include the estrogen receptor (ER), progesterone (PR), and human epidermal growth factor (EGFR). Inhibitors of these receptors could be interesting therapeutic candidates treatment management (BC). Aim: This study used GC-MS HPLC to identify bioactive compounds in Pleurotus ostreatus (P. ostreatus) extracts applied silico methods potent EGFR, ER, PR inhibitors from as potential drug candidates. Method: were chemicals P. aqueous (PO-A), methanol (PO-M), ethanol (PO-E), chloroform (PO-C), n-hexane (PO-H). The PR, EGFR model optimization molecular docking compounds/control binding pocket simulated using AutoDock Vina PyRx. drug-likeness, pharmacokinetic, pharmacodynamic features prospective leads all anticipated. Result: results indicated existence 29 PO-A, 36 PO-M PO-E, 42 PO-C, 22 PO-H extracts. With only o-tolylamino-acetic acid (4-nitro-benzylidene)-hydrazide (-7.5 kcal mol-1) ethanolic extract bind receptor. on other hand, identified several with higher affinities than control. Ergotaman-3',6',18-trione (-8.1 mol-1), 5,10-diethoxy-2,3,7,8-tetrahydro-1H,6H-dipyrrolo[1,2-a:1',2'-d]pyrazine (-7.8 extract; (-8.4 had better affinity compared (-7.7 mol-1). Likewise, ergotaman-3',6',18-trione (-9.7 phenol, 2,4-bis(1,1-dimethyl ethyl) (-8.2 control, gefitinib (-7.9 regards EGFR. None or outperformed control any proteins. Phenols flavonoids such quercetin, luteolin, rutin, chrysin, apigenin, ellagic acid, naringenin their Conclusion: class phenols lead molecules due ability strongly proteins' receptors. These showed promising drug-like properties; they safe new creating anticancer medicines.

Language: Английский

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The Impact of Oyster Mushrooms (Pleurotus ostreatus) on the Baking Quality of Rye Flour and Nutrition Composition and Antioxidant Potential of Rye Bread

Foods, Journal Year: 2025, Volume and Issue: 14(2), P. 199 - 199

Published: Jan. 10, 2025

This study aimed to evaluate the use of oyster mushroom (Pleurotus ostreatus) powder (OMP) for producing rye bread. The raw materials were low-extract flour and OMP, which analyzed in terms their nutritional health-promoting qualities. Mixtures with OMP prepared, replacing 5, 7.5, 10% OMP. baking quality tested samples was assessed based on water absorption, falling number, amylograph swelling curve tests. laboratory test carried out using sourdough method, prepared LV2 starter cultures, bread technological, sensory, characteristics, as well antioxidant potential. characterized by a high content basic nutrition components higher addition increased value its significantly prolonged starch gelatinization time, xylolytic activity flour. enhanced bread's dietary fiber, minerals, protein, phenolic compounds, boosted Also, present pro-health due share slowly digestible starch. Incorporating 7.5% into formula positively affected sensory profile contrast

Language: Английский

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Pleurotus spp: A cosmopolitan fungi of biotechnological importance

Scientia Agropecuaria, Journal Year: 2025, Volume and Issue: 16(1), P. 79 - 91

Published: Jan. 18, 2025

The genus Pleurotus presents a multivariate species diversity due to its ability grow in different substrates and environments. Whether wild or cultivated, they are edible mushrooms, as present high nutritional value medicinal their bioactive compounds with positive health effects. aim of this review is highlight the importance Pleurotus, since it cosmopolitan mushroom, properties can be used industrial applications functional alternative for our future. Due saprophytic nature, produce enzymes that act on substrate which grow, degrading lignocellulosic material such wood, forest agricultural residues, hardwoods, wood by-products, cereal straw, bagasse, etc., thanks degradative capacity, wide range biotechnological environmental applications. In order increase production consumption not only qualities, but also nutraceutical ease cultivation, low investment cost, new ways being sought performance cultivation. Recently, research has expanded search uses genus, led an well application fields biotechnology. cultivation mushrooms represents opportunity generate sustainable process incorporate into circular economy, generating environmental, social economic benefits. use agro-industrial subsequent reuse spent compost organic fertilizer reduces amount waste ends up landfills minimizes methane production. This allows more environmentally friendly model. Therefore, necessary develop strategies promotion, marketing products derived from these fungi.

Language: Английский

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Cultivating Sporeless Pleurotus ostreatus (Pearl Oyster) Mushrooms on Alternative Space-Based Substrates under Elevated Carbon Dioxide

Gravitational and Space Research, Journal Year: 2025, Volume and Issue: 13(1), P. 1 - 20

Published: Jan. 1, 2025

Abstract Fungi are natural decomposers that degrade organic substrates for growth. On Earth, fungi grow and produce mushrooms on various substrates, often with little to no added nutrient supplements. Existing waste found board the International Space Station (ISS) such as inedible biomass from plants, clothing, plastic wastes prepackaged foods could be repurposed food production advance capacity more sustainable long-duration space missions. The sporeless oyster mushroom (Pleurotus ostreatus) strain SPX was grown seven in varied combination recipes investigate how ISS streams used cultivate mushrooms. In addition, safety analyses were performed assess feasibility of cultivation a low-risk option. Results show cotton t-shirts plants potential support ISS. By using materials already available station, upmass needed efforts is reduced products can recycled potentially yield food. This investigation intended identify incorporating crop without requirement large being brought

Language: Английский

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Molecular Docking Appraisal of Pleurotus ostreatus Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment

Bioinformatics and Biology Insights, Journal Year: 2025, Volume and Issue: 19

Published: Jan. 1, 2025

Introduction: Breast cancer (BC) is a heterogeneous disease involving network of numerous extracellular signal transduction pathways. The phosphoinositide 3-kinase (PI3K)/serine/threonine kinase (Akt)/mechanistic target rapamycin (mTOR) pathway crucial for understanding the BC development. Phosphoinositide 3-kinase, phosphatase and tensin homolog (PTEN), mTOR, Akt, 3-phosphoinositide-dependent 1 (PDK1), FoxO1, glycogen synthase 3 (GSK-3), mouse double minute 2 (MDM2), H-Ras, proapoptotic B-cell lymphoma (BCL-2) family protein (BAD) proteins are key drivers this potential therapeutic targets. Pleurotus ostreatus an edible mushroom that rich in flavonoids phenols can serve as inhibitors PI3K/Akt/mTOR pathway. Aim: This study evaluated anticancer properties P through structure-based virtual screening 22 biologically active compounds present mushroom. Method: Model optimization was carried out on PI3K, PTEN, PDK1, GSK-3, MDM2, BAD molecular docking compounds/control binding pocket were simulated AutoDock Vina PyRx. drug likeness, pharmacokinetic, pharmacodynamic features prospective leads all anticipated. Result: Several potent selected driver identified from ostreatus. Ellagic acid with affinities −8.0, −8.1, −8.2, −6.2, −7.1 kcal/mol BAD, respectively, had better affinity compared their reference drugs. Likewise, apigenin (−7.8 kcal/mol), chrysin quercetin (−6.4 chlorogenic (−6.2 kcal/mol) to H-Ras proteins, respectively. Conclusion: acid, apigenin, luteolin, quercetin, chrysin, naringenin phytochemicals seen lead molecules due ability strongly bind under Analogs these also be designed

Language: Английский

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Physicochemical, Functional, and Antioxidative Characteristics of Oyster Mushrooms

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 1655 - 1655

Published: Feb. 6, 2025

Oyster mushrooms (Pleurotus species) have gained significant attention in food science and nutrition due to their exceptional nutritional functional properties. This review examines various oyster mushroom species’ comprehensive physicochemical characteristics, attributes, antioxidative Through analysis of current literature, we establish that contain substantial amounts protein (15–30%), carbohydrates (43–60%), dietary fibre, essential micronutrients while maintaining low-fat content (~1.2%). The demonstrate antioxidant activity through compounds such as ergothioneine, phenolics, flavonoids, with different species showing varying levels bioactive compounds. Scientific studies reveal processing methods, particularly drying techniques, significantly impact composition Notable findings include the identification specific coloured varieties, pink chromoprotein Pleurotus djamor melanin types, which contribute both aesthetic

Language: Английский

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Conversion of grape pomace into fungal biomass: a study of Pleurotus cultivation for a sustainable agro-residue management

Chemical and Biological Technologies in Agriculture, Journal Year: 2025, Volume and Issue: 12(1)

Published: Feb. 17, 2025

Language: Английский

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