World Journal of Stem Cells,
Journal Year:
2024,
Volume and Issue:
16(12), P. 1062 - 1085
Published: Dec. 12, 2024
BACKGROUND
Mesenchymal
stem
cells
(MSCs)
are
capable
of
self-renewal
and
differentiation,
extensive
studies
have
demonstrated
their
therapeutic
potential
in
atherosclerosis
(AS).
AIM
To
conduct
a
bibliometric
analysis
on
the
use
MSC
therapy
for
AS
over
past
two
decades,
assess
key
trends
provide
insights
future
research
directions.
METHODS
We
systematically
searched
Web
Science
Core
Collection
database
articles
published
between
1999
2023,
yielding
total
556
articles.
Visual
representation
information
were
facilitated
using
CiteSpace,
R
package
‘bibliometrix’
VOSviewer.
RESULTS
The
analyzed
predominantly
from
52
countries/regions,
with
prominent
contributions
China
United
States.
A
cohort
3057
authors
contributed
to
these
publications,
works
Libby
P
distinguished
by
influence
citation
count.
Int
J
Mol
Sci
has
emerged
as
journal
highest
publication
volume,
prominently
disseminating
influential
papers
identifying
outbreaks.
Furthermore,
our
identified
current
hotspots
within
field,
focusing
vascular
progenitor
cells,
inflammatory
mechanisms,
extracellular
vesicles.
Emerging
frontiers,
such
vesicles
oxidative
stress,
been
highlighted
areas
burgeoning
interest.
Finally,
we
offer
perspectives
status
directions
AS.
CONCLUSION
This
comprehensive
provides
valuable
advancing
scientific
By
elucidating
pivotal
directions,
this
study
aimed
foster
innovation
promote
progress
disciplines
thereby
contributing
knowledge
clinical
practice.
Clinical and Experimental Medicine,
Journal Year:
2023,
Volume and Issue:
23(7), P. 3549 - 3564
Published: July 3, 2023
Abstract
Background
Many
studies
have
shown
an
association
between
COVID-19
and
autoimmune
diseases
(ADs).
Studies
on
ADs
also
increased
significantly,
but
there
is
no
bibliometric
analysis
to
summarize
the
ADs.
The
purpose
of
this
study
was
perform
a
visual
published
related
Methods
Based
Web
Science
Core
Collection
SCI-Expanded
database,
we
utilize
Excel
2019
visualization
tools
Co-Occurrence13.2
(COOC13.2),
VOSviewer,
CiteSpace,
HistCite
for
analysis.
Results
A
total
1736
kinds
papers
were
included,
number
presented
overall
increasing
trend.
country/region
with
most
publications
USA,
institution
Harvard
Medical
School,
author
Yehuda
Shoenfeld
from
Israel,
journal
Frontiers
in
Immunology
.
Research
hotspots
include
immune
responses
(such
as
cytokines
storm),
multisystem
systemic
lupus
erythematosus,
rheumatoid
arthritis,
multiple
sclerosis),
treatment
modalities
hydroxychloroquine,
rituximab),
vaccination
mechanisms
autoantibodies,
molecular
mimicry).
future
research
direction
may
be
ideas
NF-κB,
hyperinflammation,
antiphospholipid
antibodies,
neutrophil
extracellular
traps,
granulocyte-macrophage
colony-stimulating
factor),
other
cross-diseases
inflammatory
bowel
disease,
chronic
mucocutaneous
candidiasis,
acute
respiratory
distress
syndrome).
Conclusion
growth
rate
regarding
has
risen
sharply.
Our
results
can
help
researchers
grasp
current
status
find
new
directions
future.
International Journal of Medical Sciences,
Journal Year:
2023,
Volume and Issue:
21(1), P. 151 - 168
Published: Nov. 15, 2023
Ischemic
stroke
is
a
common
cerebrovascular
accident
with
high
risk
of
neurological
deficits.
Stem
cell
therapy
has
progressively
attracted
the
interest
scientists
and
clinicians
due
to
benefits
promoting
neural
regeneration
regulating
microenvironment
surrounding
lesion
after
ischemic
stroke.
Our
study
aimed
evaluate
development
trends
research
hotspots
in
field
stem
cells
Medicine,
Journal Year:
2023,
Volume and Issue:
102(51), P. e36545 - e36545
Published: Dec. 22, 2023
In
this
study,
we
used
CiteSpace
and
VOSviewer
to
create
a
bibliometric
visualization
of
research
papers
relating
stroke
magnetic
resonance
imaging
(MRI)
between
2000
2022.
To
fully
understand
the
trends
hotspots
in
MRI
provide
new
perspectives
for
future
studies.The
Web
Science
Core
Collection
was
selected
as
source
data
paper.
Using
VOSviewer,
publications
were
analyzed
authors,
countries,
institutions,
journals,
references,
keywords.We
found
1423
after
searching
removing
duplicates,
which
indicated
an
upward
trend
over
previous
23
years.
Fiebach
J.B.
is
most
published
author
(21
publications),
Hacke
W.
cited
(213
citations),
United
States
(449
publications)
Harvard
University
(86
are
prolific
nations
institutions.
Stroke
journal
with
co-citations
(1275)
(171)
published.
The
representative
reference
1995
article
by
Marler
et
al,
received
115
citations
had
top
3
co-occurring
keywords:
stroke,
imaging,
MRI.
Nogueria
al
showed
strongest
citation
burst
at
end
2022
(strength
=
17.32).
High-frequency
keywords
recent
years
time,
association,
functional
connectivity,
thrombectomy,
rehabilitation.This
study
provides
scientific
perspective
on
research,
valuable
information
researchers
current
status
hotspots,
trends,
guides
directions.
Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: July 31, 2023
Abstract
Oxidative
stress
is
widely
involved
in
the
pathological
process
of
ischemic
stroke
and
ischemia-reperfusion.
Several
research
have
demonstrated
that
eliminating
or
reducing
oxidative
can
alleviate
changes
stroke.
However,
current
clinical
antioxidant
treatment
did
not
always
perform
as
expected.
This
bibliometric
aims
to
identify
trends,
topics,
hotspots
evolution
on
field
stroke,
find
potentially
strategies
future
treatment.
Relevant
publications
were
searched
from
Web
Science
(WOS)
Core
Collection
databases
(2001–2022).
VOSviewer
was
used
visualize
analyze
development
trends
hotspots.
In
number
increased
significantly
2001
2022.
China
USA
leading
countries
for
publication
output.
The
most
prolific
institutions
Stanford
University.
Journal
Cerebral
Blood
Flow
Metabolism
Stroke
cited
journals.
topics
this
include
inflammation
with
stress,
mitochondrial
damage
reperfusion
injury,
cognitive
impairment
basic
translation
stress.
Moreover,
"NLRP3
inflammasome",
"autophagy",
"mitophagy",
"miRNA",
"ferroptosis"
"signaling
pathway"
are
emerging
recent
years.
At
present,
multi-target
regulation
focusing
multi-mechanism
crosstalk
has
progressed
across
period,
while
challenges
come
transformation
application.
New
detection
technology
new
nanomaterials
expected
integrate
into
better.
