The role of P450 enzymes in malaria and other vector‐borne infectious diseases DOI Creative Commons
Oleksii Skorokhod,

Ekaterina Vostokova,

Gianfranco Gilardi

et al.

BioFactors, Journal Year: 2023, Volume and Issue: 50(1), P. 16 - 32

Published: Aug. 9, 2023

Abstract Vector‐borne infectious diseases are still an important global health problem. Malaria is the most among them, mainly pediatric, life‐threatening disease. and other vector‐borne disorders caused by parasites, bacteria, viruses have a strong impact on public significant economic costs. Most could be prevented vector control, with attention to ecological biodiversity conservation aspects. Chemical control pesticides insecticides widely used as measure of prevention although increasing resistance serious issue in control. Metabolic common mechanism poses big challenge. Insect enzyme systems, including monooxygenase CYP P450 enzymes, employed vectors metabolize thus causing resistance. The discovery application natural specific inhibitors/blockers enzymes synergists for commonly will contribute “greening” insecticides. Besides CYPs, host also exploited fight against diseases: using mostly their detoxifying properties involvement immune response. Here, we review published research data from all players infections, that is, pathogens, vectors, hosts, regarding potential role CYPs We discuss strategies how exploit cytochromes disease

Language: Английский

Present status of insecticide impacts and eco-friendly approaches for remediation-a review DOI
Selvaraj Barathi,

Nadana Sabapathi,

Sabariswaran Kandasamy

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 240, P. 117432 - 117432

Published: Oct. 20, 2023

Language: Английский

Citations

54
Detoxification of phoxim by a gut bacterium of Delia antiqua DOI
Fangyuan Zhou, Xiaoqing Wu, Susu Fan

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 943, P. 173866 - 173866

Published: June 9, 2024

Language: Английский

Citations

31
Environmental fate and ecotoxicological behaviour of pesticides and insecticides in non-target environments: Nanotechnology-based mitigation strategies DOI
Punniyakotti Parthipan,

Saranya Vinayagam,

Rajaram Rajamohan

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113349 - 113349

Published: June 17, 2024

Language: Английский

Citations

23
Mixed insect pest populations of Diaspididae species under control of oligonucleotide insecticides: 3′-end nucleotide matters DOI
Nikita V. Gal’chinsky, Ekaterina Yatskova, Ilya Novikov

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 200, P. 105838 - 105838

Published: Feb. 22, 2024

Language: Английский

Citations

13
Laboratory and field efficacy of natural products against the invasive pest Halyomorpha halys and side effects on the biocontrol agent Trissolcus japonicus DOI Creative Commons
Elena Chierici,

Elisa Marchetti,

Adriana Poccia

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 7, 2025

Language: Английский

Citations

2
Jasmonic Acid (JA) Signaling Pathway in Rice Defense Against Chilo suppressalis Infestation DOI Creative Commons
Andrews Danso Ofori, Wei Su, Tengda Zheng

et al.

Rice, Journal Year: 2025, Volume and Issue: 18(1)

Published: Feb. 18, 2025

Jasmonic acid (JA) signaling plays a crucial role in rice defense against the striped stem borer, Chilo suppressalis, notorious pest causing significant yield losses. This review explores current understanding of JA-mediated mechanisms rice, focusing on molecular basis, regulatory elements, and practical implications for management. JA biosynthesis pathways are induced upon C. suppressalis infestation, leading to activation various responses. These include upregulation JA-responsive genes involved production proteinase inhibitors, volatile organic compounds, other defensive compounds. The also discusses crosstalk between hormonal pathways, such as salicylic ethylene, fine-tuning Structural modifications plants, cell wall reinforcement accumulation secondary metabolites, have been highlighted key components suppressalis. Furthermore, applications this knowledge breeding insect-resistant varieties developing sustainable management strategies were explored. Future research directions proposed further elucidate complexities rice-insect interactions harness enhance crop protection.

Language: Английский

Citations

1
Recent insights into pesticide resistance mechanisms in Plutella xylostella and possible management strategies DOI

Muhammad Shehzad,

Imran Bodlah, Junaid Ali Siddiqui

et al.

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(42), P. 95296 - 95311

Published: Aug. 22, 2023

Language: Английский

Citations

23
Enthralling genetic regulatory mechanisms meddling insecticide resistance development in insects: role of transcriptional and post-transcriptional events DOI Creative Commons

Chandramohan Muthu Lakshmi Bavithra,

M. Murugan,

Shanmugasundaram Pavithran

et al.

Frontiers in Molecular Biosciences, Journal Year: 2023, Volume and Issue: 10

Published: Sept. 6, 2023

Insecticide resistance in insects severely threatens both human health and agriculture, making insecticides less compelling valuable, leading to frequent pest management failures, rising input costs, lowering crop yields, disastrous public health. results from multiple factors, mainly indiscriminate insecticide usage mounted selection pressure on insect populations. Insects respond stress at the cellular level by modest yet significant genetic propagations. Transcriptional, co-transcriptional, post-transcriptional regulatory signals of cells organisms regulate intricate processes gene expressions churning information transcriptional units into proteins non-coding transcripts. Upregulation detoxification enzymes, notably cytochrome P450s (CYPs), glutathione S-transferases (GSTs), esterases [carboxyl choline esterase (CCE), carboxyl (CarE)] ATP Binding Cassettes (ABC) level, modification target sites, decreased penetration, or higher excretion are noted physiological responses. The pathways such as AhR/ARNT, Nuclear receptors, CncC/Keap1, MAPK/CREB, GPCR/cAMP/PKA were found genes level. Post-transcriptional changes RNAs (ncRNAs) microRNAs (miRNA), long (lncRNA), epitranscriptomics, including RNA methylation, reported resistant insects. Additionally, modifications mutations sites copy number variations (CNV) also influencing resistance. Therefore, these intricacies may decrease sensitivity, altering concentrations activities involved interactions detoxification. episodes levels pertinent responses extensively covered this review. An overview molecular mechanisms underlying biological rhythms allows for developing alternative control methods focus vulnerabilities, employing reverse genetics approaches like interference (RNAi) technology silence particular resistance-related sustained management.

Language: Английский

Citations

22
Insecticidal Activity of Green Synthesized Silver Nanoparticles from Pelargonium Citronellum against Citrus Mealybug, Planococcus Citri DOI Open Access
Thamer Y. Mutter, Omar M. Hassan

Plant Protection, Journal Year: 2024, Volume and Issue: 8(1), P. 69 - 78

Published: March 27, 2024

Planococcus citri is a common insect pest that poses serious threat to citrus crops. Treatment of with chemical pesticides causes harm humans, animals, and the environment. This study aimed use silver nanoparticles as potential alternatives control this agricultural pest. Silver (AgNPs) have been identified using X-ray diffraction (XRD), ultraviolet-visible (UV-Vis) spectroscopy, scanning electron microscopy (SEM). An absorbance peak at 425 nm in UV-Vis spectrum showed existence AgNPs due plasmon resonance. XRD patterns verified possess highly crystalline structure. SEM imaging were spherical shape an average size 12.4 nm. Toxicological tests prepared they are effective insecticidal activities different stages mealybug. Using synthesized for more than 72 hours treatment concentration 100 ppm resulted highest killing rates 40.0, 68.0, 70.0% development three mealybug, including eggs, first age nymphs, adult females, respectively. The lowest percentage efficacy was recorded 5 ppm, reaching 62.75 4.6 % after 3 7 days, To our knowledge, it noteworthy report successfully from extract Pelargonium citronellum time. results demonstrated natural extracts source manage mealybugs.

Language: Английский

Citations

9
Residue of Pesticides in Fruits, Vegetables, and Their Management in Ethiopia DOI Creative Commons
Yohannes Gelaye, Belete Negash

Journal of Chemistry, Journal Year: 2024, Volume and Issue: 2024, P. 1 - 16

Published: Jan. 3, 2024

In Ethiopia, using pesticides to manage pests in the growing of fruits and vegetables is a standard practice. Various classes have been approved combat pests, but majority those use now are outdated broad-spectrum insecticides with significant residual effects on crops freshly eaten vegetables. This review reveals that Ethiopia’s assessment pesticide level has lacking. According reviewed literature, often treated many countries levels. However, Ethiopia not adequately reported this issue. Furthermore, due lack knowledge regarding impact residues human health, Ethiopians frequently improperly control The consumers eat their unprocessed, without washing or cooking them first. To reduce risk for consumer safety battle health toxic chemicals humans, monitoring raising awareness about adverse humans urgently needed. Before they may be registered sold, as well environment must also undergo proper testing evaluation. New generations fewer side developed. By washing, peeling, canning, boiling before consumption, detrimental can minimized.

Language: Английский

Citations

8