International Journal of Science and Research Archive,
Journal Year:
2024,
Volume and Issue:
12(1), P. 2115 - 2124
Published: May 30, 2024
Two
mathematical
models
of
polyphenols
extraction
from
green
tea
leaves
were
tested:
Peleg’s
model
and
First-order
model.
Thermodynamical
parameters
the
process
determined.
For
we
got
following
analytical
equation:
Ct=
t/(0.2570207+0.0324377*t).
Ct
is
a
concentration
in
extract
at
time
t.
equation
describing
was
as
follows:
Ct=23.09278*(1-exp(-0.1418264*t)).
Goodness
fit
both
high
but
first-order
prognosed
equilibrium
infusion
with
much
more
precisely
than
Activation
energy
for
equal
to
2798
j/mol.
Entropy
change
(ΔS)
this
52
(J,
(mol,
K−1)),
enthalpy
(ΔH)
16304
(Jmol−1).
The
ΔG
value
gradually
decreased
temperature
increased,
indicating
that
increasing
can
make
easier.
First
Order
Model
shown
be
well
process.
most
useful
conditions
70
℃
20
min.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(8), P. 1603 - 1603
Published: Aug. 11, 2023
The
brain's
sensitivity
to
oxidative
stress
and
neuronal
cell
death
requires
effective
pharmacotherapy
approaches.
Current
pharmacological
therapies
are
frequently
ineffective
display
negative
side
effects.
Bioactive
chemicals
found
in
plants
may
provide
a
potential
alternative
due
their
antioxidant
neuroprotective
properties
can
be
used
therapy
the
management
of
variety
neuropsychiatric,
neurodevelopmental,
neurodegenerative
illnesses.
Several
natural
products,
including
vitamin
C,
Cammelia
sinensis
polyphenols,
Hypericum
perforatum,
Crocus
sativus
have
shown
promise
lowering
treating
symptoms
major
depressive
disorder
(MDD).
Similarly,
bioactive
compounds
such
as
curcumin,
luteolin,
resveratrol,
quercetin,
like
Acorus
gramineus,
Rhodiola
rosea,
Ginkgo
biloba
associated
with
effects
symptom
improvement
neurodevelopmental
disorders
autism
spectrum
(ASD)
attention
deficit/hyperactivity
(ADHD).
Furthermore,
diseases,
from
Morinda
lucida,
Glutinous
rehmannia
neurological
improvement.
Further
study
clinical
samples
is
required
thoroughly
investigate
therapeutic
advantages
these
substances
for
persons
suffering
Exploration of neuroscience,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 24, 2025
Neurodegenerative
disorders,
including
Alzheimer’s,
Parkinson’s,
Huntington’s,
and
amyotrophic
lateral
sclerosis,
are
among
the
most
significant
health
concerns
worldwide,
characterized
by
neuronal
dysfunction,
oxidative
stress,
neuroinflammation,
protein
misfolding.
Epigallocatechin
gallate,
a
green
tea
polyphenol,
has
been
reported
to
possess
multifaceted
neuroprotective
properties.
It
reduces
stress
through
free
radical
scavenging,
activation
of
antioxidant
enzymes,
stabilization
mitochondrial
function.
also
inhibits
neuroinflammation
modulation
key
signaling
pathways.
suppresses
amyloid-beta
aggregation
in
Alzheimer’s
alpha-synuclein
fibrillation
thus
attenuating
toxic
accumulation.
Its
activity
induction
autophagy
promotion
synaptic
plasticity
supports
survival
However,
low
bioavailability
metabolic
instability
hinder
its
translation
into
clinic.
Strategies
nanoparticle
encapsulation,
structural
modifications,
combination
therapies
being
explored
overcome
these
challenges.
Future
research
could
establish
epigallocatechin
gallate
as
viable
candidate
for
managing
neurodegenerative
disorders.
