Journal of Nanoparticle Research, Journal Year: 2025, Volume and Issue: 27(4)
Published: April 1, 2025
Language: Английский
Journal of Medicine Surgery and Public Health, Journal Year: 2024, Volume and Issue: 2, P. 100081 - 100081
Published: March 2, 2024
Antimicrobial resistance (AMR) is a critical global health issue driven by antibiotic misuse and overuse in various sectors, leading to the emergence of resistant microorganisms. The history AMR dates back discovery penicillin, with rise multidrug-resistant pathogens posing significant challenges healthcare systems worldwide. antibiotics human animal health, as well agriculture, contributes spread genes, creating "Silent Pandemic" that could surpass other causes mortality 2050. affects both humans animals, treating infections. Various mechanisms, such enzymatic modification biofilm formation, enable microbes withstand effects antibiotics. lack effective threatens routine medical procedures lead millions deaths annually if left unchecked. economic impact substantial, projected losses trillions dollars financial burdens on agriculture. Artificial intelligence being explored tool combat improving diagnostics treatment strategies, although data quality algorithmic biases exist. To address effectively, One Health approach considers human, animal, environmental factors crucial. This includes enhancing surveillance systems, promoting stewardship programs, investing research development for new antimicrobial options. Public awareness, education, international collaboration are essential combating preserving efficacy future generations.
Language: Английский
Citations
204
Infection and Drug Resistance, Journal Year: 2023, Volume and Issue: Volume 16, P. 7515 - 7545
Published: Dec. 1, 2023
Abstract: Antimicrobial resistance, referring to microorganisms' capability subsist and proliferate even when there are antimicrobials is a foremost threat public health globally. The appearance of antimicrobial resistance can be ascribed anthropological, animal, environmental factors. Human-related causes include overuse misuse in medicine, antibiotic-containing cosmetics biocides utilization, inadequate sanitation hygiene settings. Prophylactic therapeutic overuse, using as feed additives, microbes resistant antibiotics genes animal excreta, residue found animal-origin food excreta animals related contributive factors for the antibiotic emergence spread. Environmental including naturally existing genes, improper disposal unused antimicrobials, contamination from waste settings, farms, pharmaceutical industries, use agricultural chemicals facilitatet its Wildlife has plausible role Adopting one-health approach involving properly humans, improving spaces implementing coordinated governmental regulations crucial combating resistance. Collaborative cooperative involvement stakeholders public, veterinary ecological sectors circumvent problem effectively. Keywords: one health, gene, environment, wildlife
Language: Английский
Citations
59
Plant Nano Biology, Journal Year: 2024, Volume and Issue: 8, P. 100070 - 100070
Published: April 16, 2024
This article examines the viability of utilizing plant biomolecules in environmentally sustainable synthesis copper nanoparticles (Cu NPs). By harnessing their intrinsic capabilities reduction and capping, plants present an friendly economically viable substitute for conventional techniques. Through manipulation diverse parameters throughout procedure, scientists are capable attaining Cu NPs desired shapes sizes, thereby customizing them to suit particular applications. review centers on owing its cost-effectiveness comparison other frequently utilized metals such as gold silver. It explores mechanisms that govern NPs. We conduct exhaustive analysis wide-ranging medical healthcare applications, emphasizing capacity fundamentally transform numerous treatment approaches. Furthermore, offers valuable perspectives alternative techniques, facilitating a comparative evaluation enabling well-informed choices be made regarding integration knowledge methods, wide range practical implementations, economic factors, objective this is furnish asset scientists, researchers, practitioners who investigating propel progress.
Language: Английский
Citations
20
Materials, Journal Year: 2022, Volume and Issue: 15(15), P. 5392 - 5392
Published: Aug. 5, 2022
Water contamination is one of the most urgent concerns confronting world today. Heavy metal poisoning aquatic systems has piqued interest various researchers due to high toxicity and carcinogenic consequences it on living organisms. Due their exceptional attributes such as strong reactivity, huge surface area, outstanding mechanical properties, nanomaterials are being produced employed in water treatment. In this review, recent advances use nanoadsorptive membrane for wastewater treatment heavy removal extensively discussed. These materials include carbon-based nanostructures, nanoparticles, oxide nanocomposites, layered double hydroxide-based compounds. Furthermore, relevant properties nanostructures implications performance highlighted. The hydrophilicity, pore size, skin thickness, porosity, roughness these can help permeability membrane. Other charge modification strength improve adsorption effectiveness membranes during Various nanocomposite fabrication techniques also reviewed. This study important because gives information roles
Language: Английский
Citations
61
Polymers, Journal Year: 2022, Volume and Issue: 14(15), P. 3126 - 3126
Published: July 31, 2022
Temperature-induced, rapid changes in the viscosity and reproducible 3-D structure formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell scaffold or drug reservoir. Moreover, hydrogels’ minimum invasiveness, high biocompatibility, facile elimination from body have gathered lot of attention researchers. This review article attempts present complete picture exhaustive arena, including synthesis, mechanism, biomedical applications thermosensitive hydrogels. A special section on intellectual property marketed products tries shed some light commercial potential
Language: Английский
Citations
54
Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 84, P. 104447 - 104447
Published: April 12, 2023
Language: Английский
Citations
35
Applied Surface Science, Journal Year: 2024, Volume and Issue: 662, P. 160098 - 160098
Published: April 13, 2024
Language: Английский
Citations
11
Life, Journal Year: 2024, Volume and Issue: 14(4), P. 468 - 468
Published: April 3, 2024
Periodontitis, a prevalent oral condition, is facing difficulties in therapeutic approaches, sometimes leading to failure. This literature review was conducted investigate the diversity of other approaches and their potential contributions successful management disease. research scrutinized alterations microbial imbalances crucial species, which contribute significantly pathogenesis periodontitis. Within limitations this study, we highlight importance understanding treatment plan’s role periodontitis disease, opening way for further innovative plans mitigate impact on health. will aid both healthcare professionals patients preventing effectively treating periodontitis, ultimately improving health outcomes overall systemic well-being.
Language: Английский
Citations
9
Antibiotics, Journal Year: 2025, Volume and Issue: 14(1), P. 90 - 90
Published: Jan. 14, 2025
This review investigates the levels of antibiotic residues in animal products, types antibiotics, and their possible impact on human health Africa. The literature search involved use a systematic survey using data that were published from Africa 2015 to 2024. terms used Boolean operators with keywords such as residues, antibiotics products Africa, health. Only research conducted was present study. findings showed most prevalent groups aminoglycoside, macrolides, β-lactams, fluoroquinolones, tetracyclines sulfonamides, phenicols. Tetracycline residue 43% mostly East followed by sulfonamides at 19%, β-lactams 16%; higher than World Health Organization permissible limit. Noncompliance withdrawal periods maximum limits for food-producing animals may lead negative outcomes allergic reactions, teratogenicity, carcinogenicity, microbiome alterations, and, notably, resistance. As result, there is need constant monitoring addition consideration alternatives order avoid implications.
Language: Английский
Citations
1
Oxidative Medicine and Cellular Longevity, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 27
Published: Aug. 22, 2022
Based on the diverse physiological influence, impact of glial cells has become much more evident neurological illnesses, resulting in origins many diseases appearing to be convoluted than previously happened. Since disorders are often random and unknown, hence construction animal models is difficult build, representing a small fraction people with gene mutation. As result, an immediate necessity grown work within vitro techniques for examining these illnesses. scientific community recognizes cell-autonomous contributions variety central nervous system therapeutic involving stem treating gaining traction. The use derived from sources increasingly being used replace both neuronal tissue. brain’s energy demands necessitate reliance neurons order it function properly. Furthermore, have functions terms regulating their own metabolic activities, as well collaborating via secreted signaling or guidance molecules, forming complex network neuron-glial connections health sickness. Emerging data reveals that changes can cause morphological functional conjunction dysfunction under disease situations, highlighting importance neuron-glia interactions pathophysiology In this context, required improve our understanding mechanisms create potential novel therapeutics. According research, synaptic malfunction one features various mental diseases, acting key ingredients not only synapse formation, growth, plasticity but also neuroinflammation homeostasis which creates critical capacity focused sensory system. goal review article elaborate state-of-the-art information few cell types situated (CNS) highlight role onset progression disorders.
Language: Английский
Citations
35