Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(11), P. 2270 - 2270
Published: Nov. 17, 2022
The
relationship
between
oxidative
stress
and
skin
aging/disorders
is
well
established.
Many
topical
oral
antioxidants
(vitamins
C
E,
carotenoids,
polyphenols)
have
been
proposed
to
protect
the
against
deleterious
effect
induced
by
increased
reactive
oxygen
species
production,
particularly
in
context
of
sun
exposure.
In
this
review,
we
focused
on
combination
vitamin
E
selenium
taken
supplements
since
both
molecules
act
synergy
either
non-enzymatic
enzymatic
pathways
eliminate
lipids
peroxides,
which
are
strongly
implicated
hair
disorders.
Frontiers in Physiology,
Journal Year:
2023,
Volume and Issue:
14
Published: June 30, 2023
Introduction:
Aging
is
a
process
characterised
by
decline
in
physiological
functions.
Reactive
species
play
crucial
role
the
aging
rate.
Due
to
close
relationship
between
and
oxidative
stress,
functional
foods
rich
phytochemicals
are
excellent
candidates
neutralise
age-related
changes.
Aim:
This
investigation
aims
verify
potential
protective
of
bergamot
(
Citrus
bergamia
,
Femminello
cultivar)
peel
juice
extract
model
represented
human
red
blood
cells
(RBCs)
exposed
D-Galactose
(DGal).
Methods:
Bergamot
extracts
were
subjected
RP-HPLC/PDA/MS
for
determination
their
composition
bioactive
compounds.
Markers
including
ROS
production,
thiobarbituric
acid
reactive
substances
(TBARS)
levels
-a
marker
lipid
peroxidation,
oxidation
total
protein
sulfhydryl
groups,
as
well
expression
anion
exchange
capability
band
3
glycated
haemoglobin
(A1c)
production
have
been
investigated
RBCs
treated
with
D-Gal
24
h,
or
without
pre-incubation
15
min
5
μg/mL
extract.
In
addition,
activity
endogenous
antioxidant
system,
catalase
(CAT)
superoxide
dismutase
(SOD),
diversion
RBC
metabolism
from
glycolysis
towards
pentose
phosphate
pathway
shunt,
denoted
activation
glucose-6-phosphate
dehydrogenase
(G6PDH),
explored.
Results:
Data
shown
here
suggest
that
i)
prevented
D-Gal-induced
consequently,
stress
injury
biological
macromolecules
membrane
lipids
proteins;
ii)
significantly
restored
alterations
distribution
ion
transport
kinetics
3;
iii)
blunted
A1c
production;
iv)
effectively
impeded
over-activation
enzymes
CAT
SOD;
v)
G6PDH.
Discussion:
These
results
further
contribute
shed
light
on
mechanisms
identify
food
natural
antioxidants
useful
prevention
treatment
stress-related
changes,
which
may
lead
pathological
states
during
aging.
Aging,
Journal Year:
2023,
Volume and Issue:
15(2), P. 371 - 395
Published: Jan. 5, 2023
Aging
|
doi:10.18632/aging.204467.
Drew
R.
Nannini,
Brian
T.
Joyce,
Yinan
Zheng,
Tao
Gao,
Jun
Wang,
Lei
Liu,
David
Jacobs,
Pamela
J.
Schreiner,
Chunyu
Qi
Dai,
Steve
Horvath,
Ake
Lu,
Kristine
Yaffe,
Philip
Greenland,
Donald
M.
Lloyd-Jones,
Lifang
Hou
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(2), P. 217 - 217
Published: Feb. 8, 2024
Plant
extracts
rich
in
phenolic
compounds
have
been
reported
to
exert
different
bioactive
properties.
Despite
the
fact
that
there
are
plant
with
completely
compositions,
many
of
them
similar
beneficial
Thus,
structure–bioactivity
relationship
mechanisms
not
yet
known
detail
for
specific
classes
compounds.
In
this
context,
work
aims
demonstrate
compositions
versus
targets.
For
purpose,
five
matrices
(Theobroma
cacao,
Hibiscus
sabdariffa,
Silybum
marianum,
Lippia
citriodora,
and
Olea
europaea)
were
selected
cover
which
confirmed
by
phytochemical
characterization
analysis
performed
HPLC-ESI-qTOF-MS.
The
targets
evaluated
antioxidant
potential,
free
radical
scavenging
inhibitory
capacity
enzymes
involved
inflammatory
processes,
skin
aging,
neuroprotection.
results
showed
despite
matrices,
they
all
a
positive
effect
most
assays.
particular,
very
contents,
such
as
T.
cacao
S.
exerted
power
processes
aging.
It
should
also
be
noted
H.
sabdariffa
had
low
content
but
nevertheless
stood
out
their
anti-radical
capacity.
Hence,
research
highlights
shared
properties
among
found
diverse
matrices.
abundance
compound
families
elevated
bioactivity
against
biological
Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(11), P. 2270 - 2270
Published: Nov. 17, 2022
The
relationship
between
oxidative
stress
and
skin
aging/disorders
is
well
established.
Many
topical
oral
antioxidants
(vitamins
C
E,
carotenoids,
polyphenols)
have
been
proposed
to
protect
the
against
deleterious
effect
induced
by
increased
reactive
oxygen
species
production,
particularly
in
context
of
sun
exposure.
In
this
review,
we
focused
on
combination
vitamin
E
selenium
taken
supplements
since
both
molecules
act
synergy
either
non-enzymatic
enzymatic
pathways
eliminate
lipids
peroxides,
which
are
strongly
implicated
hair
disorders.
