Sustainability,
Journal Year:
2023,
Volume and Issue:
15(4), P. 3268 - 3268
Published: Feb. 10, 2023
This
study
evaluated
the
functional
components
of
hazelnut
waste
products
(cuticles
and
shells)
for
potential
use
in
circular
economy.
HPLC-HRMS
ABTS
assay
were
used
to
determine
molecules
with
properties
antioxidant
capacity,
respectively.
The
capacity
cuticles
shells
was
tested
using
two
different
methods
extraction
(EtOH
50/50
acetone
40/70)
by
radical
cation
decolorization
assay.
growth
inhibition
effect
extracts
against
porcine
O138
E.
coli
F18+
microdilution
bacterial
method
confirmed
determination
minimal
inhibitory
concentration
(MIC).
results
showed
that
produced
a
higher
yield
metabolites
compared
ethanol
extraction,
exhibited
antimicrobial
potential.
acetone/water
led
identification
738
signals
453
detected
after
EtOH/water
extraction.
Through
metabolomic
analysis,
it
found
presented
much
quantitative
qualitative
polyphenolic
profile
than
did
shells.
In
addition,
revealed
had
Thus,
we
believe
hazelnut-derived
show
high
sustainable
Metabolites,
Journal Year:
2023,
Volume and Issue:
13(7), P. 871 - 871
Published: July 21, 2023
White,
green,
and
oolong
teas
are
produced
from
the
tea
plant
(Camellia
sinensis
(L.)
Kuntze)
reported
to
have
anti-obesity
hypolipidemic
effects.
The
current
study
aims
investigate
effects
of
a
mixture
nano-formulation
by
targeting
AMPK/Sirt-1/GLUT-4
axis
in
rats.
In
vitro
lipase
α-amylase
inhibition
assays
were
used
determine
active
sample,
which
was
then
incorporated
into
nanoparticle
formulation
subjected
vivo
testing
rats
measuring
expression
level
different
genes
implicated
adipogenesis
inflammation
using
qRT-PCR.
Moreover,
metabolomic
analysis
performed
for
each
extract
LC/ESI
MS/MS
coupled
chemometrics
an
attempt
find
correlation
between
constituents
extracts
their
biological
activity.
pancreatic
demonstrated
more
effective
activity
than
standards,
orlistat
acarbose,
respectively,
alone.
Thus,
herbal
its
evaluated
Intriguingly,
significantly
decreased
serum
levels
glucose
triglycerides
increased
mRNA
GLUT-4,
P-AMPK,
Sirt-1,
PPAR-γ,
induce
lipolysis
while
also
decreasing
TNF-α
ADD1/SREBP-1c,
thereby
inhibiting
associated
with
obesity.
Our
suggests
that
is
promising
therapeutic
agent
treatment
obesity
may
be
beneficial
other
metabolic
disorders
AMPK/Sirt-1/Glut-4
pathway.
Sustainability,
Journal Year:
2023,
Volume and Issue:
15(4), P. 3268 - 3268
Published: Feb. 10, 2023
This
study
evaluated
the
functional
components
of
hazelnut
waste
products
(cuticles
and
shells)
for
potential
use
in
circular
economy.
HPLC-HRMS
ABTS
assay
were
used
to
determine
molecules
with
properties
antioxidant
capacity,
respectively.
The
capacity
cuticles
shells
was
tested
using
two
different
methods
extraction
(EtOH
50/50
acetone
40/70)
by
radical
cation
decolorization
assay.
growth
inhibition
effect
extracts
against
porcine
O138
E.
coli
F18+
microdilution
bacterial
method
confirmed
determination
minimal
inhibitory
concentration
(MIC).
results
showed
that
produced
a
higher
yield
metabolites
compared
ethanol
extraction,
exhibited
antimicrobial
potential.
acetone/water
led
identification
738
signals
453
detected
after
EtOH/water
extraction.
Through
metabolomic
analysis,
it
found
presented
much
quantitative
qualitative
polyphenolic
profile
than
did
shells.
In
addition,
revealed
had
Thus,
we
believe
hazelnut-derived
show
high
sustainable
