High Altitude Medicine & Biology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
Many
Andean
highlanders
exposed
to
chronic
hypoxemia
are
susceptible
excessive
erythrocytosis
(EE)
and
mountain
sickness
(CMS).
Nocturnal
is
more
marked
than
diurnal
includes
sustained
intermittent
components.
The
potential
for
cognitive
impairments
related
nocturnal
in
this
population
has
not
been
extensively
studied,
but
improved
understanding
may
provide
opportunities
the
prevention
of
long-term
effects
EE
CMS.
The Journal of Physiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 27, 2024
Abstract
Periodic
breathing
during
sleep
at
high
altitude
is
almost
universal
among
sojourners.
Here,
in
the
context
of
acclimatization
and
adaptation,
we
provide
a
contemporary
review
on
periodic
altitude,
explore
whether
this
an
adaptive
or
maladaptive
process.
The
mechanism(s),
prevalence
role
acclimatized
lowlanders
are
contrasted
with
available
data
from
adapted
indigenous
populations
(e.g.
Andean
Tibetan
highlanders).
It
concluded
that
(1)
persists
severity
proportional
to
sleeping
altitude;
(2)
does
not
seem
coalesce
poor
quality
such
that,
acclimatization,
there
appears
be
lengthening
cycle
length
minimal
impact
average
oxygen
saturation;
(3)
highlanders
appear
demonstrate
blunting
breathing,
compared
lowlanders,
comprising
feature
withstands
negative
influences
chronic
mountain
sickness.
These
observations
indicate
no
obvious
consequences;
however,
attenuated
adaptation
therefore
potentially
reflects
trait
environment.
image
Frontiers in Physiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Sept. 4, 2023
Hypobaric
hypoxia
(HH)
characteristics
induce
impaired
cognitive
function,
reduced
concentration,
and
memory.
In
recent
years,
an
increasing
number
of
people
have
migrated
to
high-altitude
areas
for
work
study.
Headache,
sleep
disturbance,
impairment
from
HH,
severely
challenges
the
physical
mental
health
affects
their
quality
life
efficiency.
This
review
summarizes
manifestations,
mechanisms,
preventive
therapeutic
methods
HH
environment
affecting
function
provides
theoretical
references
exploring
treating
high
altitude-induced
impairment.
Physiology & Behavior,
Journal Year:
2023,
Volume and Issue:
274, P. 114409 - 114409
Published: Nov. 16, 2023
Both
sleep
deprivation
and
hypoxia
have
been
shown
to
impair
executive
function.
Conversely,
moderate
intensity
exercise
is
known
improve
In
a
multi-experiment
study,
we
tested
the
hypotheses
that
would
ameliorate
any
decline
in
function
after
i)
three
consecutive
nights
of
partial
(PSD)
(Experiment
1)
ii)
isolated
combined
effects
single
night
total
(TSD)
acute
2).
Using
rigorous
randomised
controlled
crossover
design,
12
healthy
participants
volunteered
each
experiment
(24
total,
5
females).
both
experiments
seven
(2-choice
reaction
time,
logical
relations,
manikin,
mathematical
processing,
1-back,
2-back,
3-back)
tasks
were
completed
at
rest
during
20-min
semi-recumbent,
cycling.
Tasks
following
conditions:
before
PSD
habitual
normoxia
(FIO2
=
0.12)
one
TSD
Although
on
functions
inconsistent,
(regardless
hypoxic
status)
reduced
functions.
Significantly,
regardless
or
status,
are
improved
an
bout
exercise.
These
novel
data
indicate
improves
performance
TSD,
status.
The
key
determinants
and/or
mechanism(s)
responsible
for
this
improvement
still
need
be
elucidated.
Future
work
should
seek
identify
these
mechanisms
translate
significant
findings
into
occupational
skilled
settings.
Sports Psychiatry,
Journal Year:
2024,
Volume and Issue:
3(4), P. 197 - 208
Published: Nov. 1, 2024
Abstract:
Introduction:
The
human
brain
is
a
highly
oxygen-dependent
organ.
Low
environmental
oxygen
availability
(e.g.,
hypobaric
hypoxia
at
altitude)
major
challenge
to
the
and
numerous
endogenous
cellular
systemic
responses
therefore
are
in
place
mitigate
hypoxic
stress.
When
dose
of
stress
surpasses
adaptive
capabilities
brain,
cerebral
forms
high-altitude
illnesses
can
develop,
prevalence
which
increases
with
altitude.
Hypoxia
also
trigger
psychotic
symptoms.
Despite
that,
effects
altitude
exposures
on
people
pre-existing
mental
disorders
surprisingly
scarcely
investigated.
Methods:
In
this
narrative
review
we
summarize
literature
brain’s
put
them
context
somatic
consequences
exposure
from
an
interdisciplinary
perspective.
Results:
We
identify
knowledge
gaps
high
clinical
relevance
related
safety
exposures,
particularly
for
individuals
disorders.
Conclusions:
Taken
together,
research
into
vulnerability
neuropsychiatric
risk
developing
symptoms
different
populations
(diseased,
healthy,
athletes)
urgently
needed
provide
appropriate
evidence-based
counselling
treatment.
PubMed,
Journal Year:
2023,
Volume and Issue:
48(10), P. 1464 - 1478
Published: Oct. 28, 2023
The
plateau
is
a
special
environment
with
low
pressure,
oxygen,
temperature,
and
high
ultraviolet
radiation.
exercise
performance
of
people
on
the
generally
reduced,
which
seriously
affects
life
health
living
in
entering
plateau.
In
recent
years,
prevention
treatment
injury
caused
by
altitude
hypoxia
has
attracted
wide
attention.
It
shown
that
higher
longer
duration
exercise,
faster
stationing,
greater
impact
people's
sports
performance.
Rapid
entry
into
long-term
stay
have
an
explosive
power,
endurance
fine
operation.
Advances
medical
technology
enable
various
methods
to
be
used
acclimate
environments.
However,
vitro
intervention
are
costly,
easy
rebound
possess
limited
effects.
Therefore,
drug
obviously
more
economical
choice.
Chemical
drugs
increase
efficiency
improving
ischemic
hypoxic
symptoms
heart
brain,
increasing
lung
ventilation
arterial
oxygenation
capacity,
accelerating
elimination
adverse
product
accumulation
after
exercise.
Single
Chinese
medicine,
patent
compound
preparations
can
improve
promoting
body
metabolism,
muscle
endurance,
enhancing
immunity,
other
mechanisms.
Traditional
medicine
unique
advantage
application
prospect
damage.
