Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults

PLoS Biology, Journal Year: 2022, Volume and Issue: 20(3), P. e3001571 - e3001571

Published: March 17, 2022

Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms sleep, as well neuroendocrine cognitive functions. Prevailing patterns do not optimally engage these actions for many individuals, but advances in our understanding the underpinning mechanisms emerging lighting technologies now present opportunities to adjust promote optimal physical mental performance. A newly developed, international standard provides a SI-compliant way quantifying influence intrinsically photosensitive, melanopsin-expressing, retinal neurons that mediate effects. The report recommendations lighting, based an expert scientific consensus expressed easily measured quantity (melanopic equivalent daylight illuminance (melaponic EDI)) defined within this standard. are supported by detailed analysis sensitivity circadian, neuroendocrine, alerting responses ocular provide straightforward framework inform design practice.

Language: Английский

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The relevance of daylight for humans

Biochemical Pharmacology, Journal Year: 2020, Volume and Issue: 191, P. 114304 - 114304

Published: Oct. 28, 2020

Daylight is ubiquitous and crucial for mammalian vision as well non-visual input to the brain via intrinsically photosensitive retinal ganglion cells (ipRGCs) that express photopigment melanopsin. The ipRGCs project circadian clock in suprachiasmatic nuclei thereby ensure entrainment 24-hour day-night cycle, changes daylength trigger appropriate seasonal behaviours. also perihabenular nucleus surrounding regions modulate mood, stress learning animals humans. Given light has strong direct effects on cognition, alertness, performance, sleep, can be considered a "drug" treat many clinical conditions. Light therapy already established winter other depressions sleep disorders. Beyond visual retina, daylight contributes prevent myopia young by its impact eye development, important Vitamin D synthesis bone health skin. sun most powerful source and, dependent dose, ultraviolet radiance toxic living organisms used disinfectant. Most research involves laboratory-based electric light, without dynamic spectral undergoes moment moment. There gap between importance of human beings amount being done this subject. taken granted an environmental factor, enjoyed or avoided, according More awareness architecture urban design beyond aesthetic values comfort may lead higher quality work environments. Although we do not yet have factual basis assumption natural overall "better" than debate mandates serious consideration sunlight just solar power but biologically necessary sustainable healthy living.

Language: Английский

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A Review of Human Physiological Responses to Light: Implications for the Development of Integrative Lighting Solutions

LEUKOS The Journal of the Illuminating Engineering Society of North America, Journal Year: 2021, Volume and Issue: 18(3), P. 387 - 414

Published: March 26, 2021

Architectural lighting has potent biological effects but applied practices that capitalize on this potential have been limited. In review, we endeavor to consolidate and synthesize key references will be useful for professionals, with the goal of supporting knowledge translation into pragmatic strategies. Specifically, explain relevant terminology, outline basic concepts, identify references, provide a balanced overview current state knowledge, highlight important remaining questions. We summarize physiological light human health well-being, including description processes underlying photic regulation circadian, neuroendocrine, neurobehavioral functions. review seminal work elucidating elements mediating potency these responses, specific attention factors critical interpreting those findings. parallel, endorse melanopic Equivalent Daylight Illuminance (Ev,melD65) as preferred measure quantify light. Ultimately, while future studies are necessary further facilitate laboratory domestic workplace settings, immediate better support is clear. Aiming integrative solutions biologically high during day low night perhaps most improvement made in order applications humans.

Language: Английский

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Chronobiology and Chronomedicine

Royal Society of Chemistry eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 23, 2024

Circadian rhythms have been shown to be ubiquitous and critically important in the experimental laboratory, accounting for difference between life death response identical stimulus. The partly endogenous nature of circadian has well documented methods their characterisation developed enabling cellular molecular mechanisms understood. Chronobiology Chronomedicine aims provide a review these underlying illustrate role brain’s suprachiasmatic nuclei ‘pace-making’ process effects caused by ‘clock genes’ present almost all cells. Beyond involved, book discusses relationship body systems, disease, proper function; particular, how disruption rhythm is associated with ill health disease status from observations made at organismic level. organised an ideal introduction postgraduate various fields, reviewing developments outlining show depth breadth chronobiology chronomedicine, as invaluable companion researchers healthcare professionals working field interest developing novel therapeutic approaches.

Language: Английский

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The sleep–circadian interface: A window into mental disorders

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(9)

Published: Feb. 23, 2024

Sleep, circadian rhythms, and mental health are reciprocally interlinked. Disruption to the quality, continuity, timing of sleep can precipitate or exacerbate psychiatric symptoms in susceptible individuals, while treatments that target sleep-circadian disturbances alleviate psychopathology. Conversely, poor disrupt clock-controlled processes. Despite progress elucidating underlying mechanisms, a cohesive approach integrates dynamic interactions between disorder with both processes is lacking. This review synthesizes recent evidence for dysfunction as transdiagnostic contributor range disorders, an emphasis on biological mechanisms. We highlight observations from adolescent young adults, who at greatest risk developing whom early detection intervention promise benefit. In particular, we aim a) integrate factors implicated pathophysiology treatment mood, anxiety, psychosis spectrum perspective; b) need reframe existing knowledge adopt integrated which recognizes interaction factors; c) identify important gaps opportunities further research.

Language: Английский

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The effect of lighting environment on task performance in buildings – A review

Energy and Buildings, Journal Year: 2020, Volume and Issue: 226, P. 110394 - 110394

Published: Aug. 12, 2020

Language: Английский

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Individual differences in light sensitivity affect sleep and circadian rhythms

SLEEP, Journal Year: 2020, Volume and Issue: 44(2)

Published: Oct. 13, 2020

Abstract Artificial lighting is omnipresent in contemporary society with disruptive consequences for human sleep and circadian rhythms because of overexposure to light, particularly the evening/night hours. Recent evidence shows large individual variations photosensitivity, such as melatonin suppression, due artificial light exposure. Despite emerging body research indicating that effects on vary dramatically across individuals, recommendations appropriate exposure real-life settings rarely consider effects. This review addresses recently identified links among traits, example, age, sex, chronotype, genetic haplotypes, hallmarks, based laboratory field studies. Target biological mechanisms differences sensitivity include occurring within retina downstream, central clock. also highlights there are wide gaps uncertainty, despite growing awareness shape physiology. These (1) why do certain traits differentially affect influence rhythms; (2) what translational value populations typically exposed at night, night shift workers; (3) magnitude population-based studies? Collectively, current findings provide strong support considering when defining optimal specifications, thus allowing personalized solutions promote quality life health.

Language: Английский

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Light, lighting and human health

Lighting Research & Technology, Journal Year: 2021, Volume and Issue: 54(2), P. 101 - 144

Published: April 28, 2021

Light can impact human health via the visual and non-visual systems originating in retina of eye or as optical radiation falling on skin. This paper provides a summary what is known about these impacts. Topics covered include aspects lighting likely to cause eyestrain headaches; increase risk falls; induce circadian disruption; enhance sleep; mitigate Alzheimer’s disease depression; produce tissue damage; alleviate diseases through phototherapy inactivate viruses germicidal irradiation. It concluded that undoubtedly influenced by lighting, but there are four conditions should be attached such simple assertion. First, either positive negative. Second, affected many factors other than lighting. Third, severity effects light exposure vary widely from short-lived trivial long-term fatal. Fourth, same have very different impacts for individuals depending their age medical status. Taken together, imply care required when judging veracity relevance broad assertions benefits health.

Language: Английский

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Evaluation of anxiety, depression and sleep quality in full-time teleworkers

Journal of Public Health, Journal Year: 2021, Volume and Issue: 44(4), P. 797 - 804

Published: May 22, 2021

Abstract Background Mental health-related positive and negative aspects of telework are understudied. This study aimed to evaluate anxiety, depression sleep quality in full-time teleworkers during lockdown imposed by the coronavirus disease 2019 (COVID-19) pandemic explore potential relationships between these variables, sociodemographic characteristics, life perceived productivity. Methods A cross-sectional was conducted on 143 teleworkers. Participants were assessed for using validated clinical instruments. Results found a high prevalence poor (74%, N = 106). reported anxiety/depressive symptoms with predominance anxiety very levels impairment. Better associated longer duration better job satisfaction, whereas use hypnotic medication higher depression/anxiety scores seem point correlation Anxiety/depression positively correlated worse negatively life. Male sex Conclusions comparison other studies performed COVID-19 as well depression. These results highlight relevance considering impact mental health.

Language: Английский

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Investigation into the daylight performance of expanded-metal shading through parametric design and multi-objective optimisation in Japan

Journal of Building Engineering, Journal Year: 2022, Volume and Issue: 51, P. 104241 - 104241

Published: Feb. 18, 2022

Language: Английский

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